Large-scale energy spectra in surface quasi-geostrophic turbulence

The large-scale energy spectrum in two-dimensional turbulence governed by the surface quasi-geostrophic (SQG) equation $$\partial_t(-\Delta)^{1/2}\psi+J(\psi,(-\Delta)^{1/2}\psi) =\mu\Delta\psi+f$$ is studied. The nonlinear transfer of this system conserves the two quadratic quantities $\Psi_1=/2$ and $\Psi_2=/2$ (kinetic energy), where $$ denotes a spatial average. The energy density $\Psi_2$ is bounded and its spectrum $\Psi_2(k)$ is shallower than $k^{-1}$ in the inverse-transfer range. For bounded turbulence, $\Psi_2(k)$ in the low-wavenumber region can be bounded by $Ck$ where $C$ is a constant independent of $k$ but dependent on the domain size. Results from numerical simulations confirming the theoretical predictions are presented.Comment: 11 pages, 4 figures, to appear in JF

Inhibition of DNA ejection from bacteriophage by Mg+2 counterions

The problem of inhibiting viral DNA ejection from bacteriophages by multivalent counterions, specifically Mg$^{+2}$ counterions, is studied. Experimentally, it is known that MgSO$_4$ salt has a strong and non-monotonic effect on the amount of DNA ejected. There exists an optimal concentration at which the minimum amount of DNA is ejected from the virus. At lower or higher concentrations, more DNA is ejected from the capsid. We propose that this phenomenon is the result of DNA overcharging by Mg$^{+2}$ multivalent counterions. As Mg$^{+2}$ concentration increases from zero, the net charge of DNA changes from negative to positive. The optimal inhibition corresponds to the Mg$^{+2}$ concentration where DNA is neutral. At lower/higher concentrations, DNA genome is charged. It prefers to be in solution to lower its electrostatic self-energy, which consequently leads to an increase in DNA ejection. By fitting our theory to available experimental data, the strength of DNA$-$DNA short range attraction energies, mediated by Mg$^{+2}$, is found to be $-$0.004 $k_BT$ per nucleotide base. This and other fitted parameters agree well with known values from other experiments and computer simulations. The parameters are also in aggreement qualitatively with values for tri- and tetra-valent counterions.Comment: 17 pages, 4 figures, improved manuscript. Submitted to J. Chem. Phys (2010

Large-scale bottleneck effect in two-dimensional turbulence

The bottleneck phenomenon in three-dimensional turbulence is generally associated with the dissipation range of the energy spectrum. In the present work, it is shown by using a two-point closure theory, that in two-dimensional turbulence it is possible to observe a bottleneck at the large scales, due to the effect of friction on the inverse energy cascade. This large-scale bottleneck is directly related to the process of energy condensation, the pile-up of energy at wavenumbers corresponding to the domain size. The link between the use of friction and the creation of space-filling structures is discussed and it is concluded that the careless use of hypofriction might reduce the inertial range of the energy spectrum

Pressure moderation and effective pressure in Navier-Stokes flows

We study the Cauchy problem of the Navier–Stokes equations by both semi-analytic and classical energy methods. The former approach provides a physical picture of how viscous effects may or may not be able to suppress singularity development. In the latter approach, we examine the pressure term that drives the dynamics of the velocity norms ||u||Lq , for q ≥ 3. A key idea behind this investigation is due to the fact that the pressure p in this term is determined upto a function of both space and |u|, say Ƥ(x, |u|), which may assume relatively broad forms. This allows us to use Ƥ as a pressure moderator in the evolution equation for ||u||Lq , whereby optimal regularity criteria can be sought by varying Ƥ within its admissible classes. New regularity criteria are derived with and without making use of the moderator. The results obtained in the absence of the moderator feature some improvement over existing criteria in the literature. Several criteria are derived in terms of the moderated (effective) pressure p+Ƥ. A simple moderation scheme and the plausibility of the present approach to the problem of Navier–Stokes regularity are discussed.PostprintPeer reviewe

U-duality as General Coordinate Transformations, and Spacetime Geometry

We show that the full global symmetry groups of all the D-dimensional maximal supergravities can be described in terms of the closure of the internal general coordinate transformations of the toroidal compactifications of D=11 supergravity and of type IIB supergravity, with type IIA/IIB T-duality providing an intertwining between the two pictures. At the quantum level, the part of the U-duality group that corresponds to the surviving discretised internal general coordinate transformations in a given picture leaves the internal torus invariant, while the part that is not described by internal general coordinate transformations can have the effect of altering the size or shape of the internal torus. For example, M-theory compactified on a large torus T^n can be related by duality to a compactification on a small torus, if and only if n\ge 3. We also discuss related issues in the toroidal compactification of the self-dual string to D=4. An appendix includes the complete results for the toroidal reduction of the bosonic sector of type IIB supergravity to arbitrary dimensions D\ge3.Comment: Latex, 28 page

Removal of antagonistic spindle forces can rescue metaphase spindle length and reduce chromosome segregation defects

Regular Abstracts - Tuesday Poster Presentations: no. 1925Metaphase describes a phase of mitosis where chromosomes are attached and oriented on the bipolar spindle for subsequent segregation at anaphase. In diverse cell types, the metaphase spindle is maintained at a relatively constant length. Metaphase spindle length is proposed to be regulated by a balance of pushing and pulling forces generated by distinct sets of spindle microtubules and their interactions with motors and microtubule-associated proteins (MAPs). Spindle length appears important for chromosome segregation fidelity, as cells with shorter or longer than normal metaphase spindles, generated through deletion or inhibition of individual mitotic motors or MAPs, showed chromosome segregation defects. To test the force balance model of spindle length control and its effect on chromosome segregation, we applied fast microfluidic temperature-control with live-cell imaging to monitor the effect of switching off different combinations of antagonistic forces in the fission yeast metaphase spindle. We show that spindle midzone proteins kinesin-5 cut7p and microtubule bundler ase1p contribute to outward pushing forces, and spindle kinetochore proteins kinesin-8 klp5/6p and dam1p contribute to inward pulling forces. Removing these proteins individually led to aberrant metaphase spindle length and chromosome segregation defects. Removing these proteins in antagonistic combination rescued the defective spindle length and, in some combinations, also partially rescued chromosome segregation defects. Our results stress the importance of proper chromosome-to-microtubule attachment over spindle length regulation for proper chromosome segregation.postprin