320 research outputs found
Noise spectroscopy and interlayer phase-coherence in bilayer quantum Hall systems
Bilayer quantum Hall systems develop strong interlayer phase-coherence when
the distance between layers is comparable to the typical distance between
electrons within a layer. The phase-coherent state has until now been
investigated primarily via transport measurements. We argue here that
interlayer current and charge-imbalance noise studies in these systems will be
able to address some of the key experimental questions. We show that the
characteristic frequency of current-noise is that of the zero wavevector
collective mode, which is sensitive to the degree of order in the system. Local
electric potential noise measured in a plane above the bilayer system on the
other hand is sensitive to finite-wavevector collective modes and hence to the
soft-magnetoroton picture of the order-disorder phase transition.Comment: 5 pages, 2 figure
Excitonic condensate and quasiparticle transport in electron-hole bilayer systems
Bilayer electron-hole systems undergo excitonic condensation when the
distance d between the layers is smaller than the typical distance between
particles within a layer. All excitons in this condensate have a fixed dipole
moment which points perpendicular to the layers, and therefore this condensate
of dipoles couples to external electromagnetic fields. We study the transport
properties of this dipolar condensate system based on a phenomenological model
which takes into account contributions from the condensate and quasiparticles.
We discuss, in particular, the drag and counterflow transport, in-plane
Josephson effect, and noise in the in-plane currents in the condensate state
which provides a direct measure of the superfluid collective-mode velocity.Comment: 7 pages, 3 figure
An optimised step-by-step protocol for measuring relative telomere length
Telomeres represent the nucleotide repeat sequences at the ends of chromosomes and are essential for chromosome stability. They can shorten at each round of DNA replication mainly because of incomplete DNA synthesis of the lagging strand. Reduced relative telomere length is associated with aging and a range of disease states. Different methods such as terminal restriction fragment analysis, real-time quantitative PCR (qPCR) and fluorescence in situ hybridization are available to measure telomere length; however, the qPCR-based method is commonly used for large population-based studies. There are multiple variations across qPCR-based methods, including the choice of the single-copy gene, primer sequences, reagents, and data analysis methods in the different reported studies so far. Here, we provide a detailed step-by-step protocol that we have optimized and successfully tested in the hands of other users. This protocol will help researchers interested in measuring relative telomere lengths in cells or across larger clinical cohort/study samples to determine associations of telomere length with health and disease
Quantum Gravity Phenomenology without Lorentz Invariance Violation: a detailed proposal
We describe a scheme for the exploration of quantum gravity phenomenology
focussing on effects that could be thought as arising from a fundamental
granularity of space-time. In contrast with the simplest assumptions, such
granularity is assumed to respect Lorentz Invariance but is otherwise left
unspecified. The proposal is fully observer covariant, it involves non-trivial
couplings of curvature to matter fields and leads to a well defined
phenomenology. We present the effective Hamiltonian which could be used to
analyze concrete experimental situations, some of which are briefly described,
and we shortly discuss the degree to which the present proposal is in line with
the fundamental ideas behind the equivalence principle.Comment: LaTeX, 24 pages. To be published in Classical and Quantum Gravit
Dipolar superfluidity in electron-hole bilayer systems
Bilayer electron-hole systems, where the electrons and holes are created via
doping and confined to separate layers, undergo excitonic condensation when the
distance between the layers is smaller than typical distance between particles
within a layer. We argue that the excitonic condensate is a novel dipolar
superfluid in which the phase of the condensate couples to the {\it gradient}
of the vector potential. We predict the existence of dipolar supercurrent which
can be tuned by an in-plane magnetic field and detected by independent contacts
to the layers. Thus the dipolar superfluid offers an example of excitonic
condensate in which the {\it composite} nature of its constituent excitons is
manifest in the macroscopic superfluid state. We also discuss various
properties of this superfluid including the role of vortices.Comment: 5 pages, 1 figure, minor changes and added few references; final
published versio
Postpartum circulating cell-free insulin DNA levels are higher in women with previous gestational diabetes mellitus who develop type 2 diabetes in later life
Background. Women with previous gestational diabetes mellitus (GDM) have evidence of postpartum β-cell dysfunction, which increases their risk of developing type 2 diabetes (T2DM) later in life. Elevated levels of circulating cell-free preproinsulin (INS) DNA correlate with dying β-cells in both mice and humans. The aim of this study was to determine if cell-free circulating INS DNA levels are higher in women with previous GDM who develop T2DM. Methods. We used droplet digital (dd) PCR to measure the levels of cell-free circulating methylated and unmethylated INS DNA in plasma from 97 women with normal glucose tolerance (NGT), 12 weeks following an index GDM pregnancy. Women were assessed for up to 10 years for the development of T2DM. Results. In the follow-up period, 22% of women developed T2DM. Compared with NGT women, total cell-free INS DNA levels were significantly higher in women who developed T2DM (P=0.02). There was no difference in cell-free circulating unmethylated and methylated INS DNA levels between NGT women and women who developed T2DM (P=0.09 and P=0.07, respectively). Conclusions. In women with a previous index GDM pregnancy, postpartum levels of cell-free circulating INS DNA are significantly higher in those women who later developed T2DM
Postpartum circulating cell-free insulin DNA levels are higher in women with previous gestational diabetes mellitus who develop type 2 diabetes in later life
Background. Women with previous gestational diabetes mellitus (GDM) have evidence of postpartum β-cell dysfunction, which increases their risk of developing type 2 diabetes (T2DM) later in life. Elevated levels of circulating cell-free preproinsulin (INS) DNA correlate with dying β-cells in both mice and humans. The aim of this study was to determine if cell-free circulating INS DNA levels are higher in women with previous GDM who develop T2DM. Methods. We used droplet digital (dd) PCR to measure the levels of cell-free circulating methylated and unmethylated INS DNA in plasma from 97 women with normal glucose tolerance (NGT), 12 weeks following an index GDM pregnancy. Women were assessed for up to 10 years for the development of T2DM. Results. In the follow-up period, 22% of women developed T2DM. Compared with NGT women, total cell-free INS DNA levels were significantly higher in women who developed T2DM (P=0.02). There was no difference in cell-free circulating unmethylated and methylated INS DNA levels between NGT women and women who developed T2DM (P=0.09 and P=0.07, respectively). Conclusions. In women with a previous index GDM pregnancy, postpartum levels of cell-free circulating INS DNA are significantly higher in those women who later developed T2DM
The elusive memristor: properties of basic electrical circuits
We present a tutorial on the properties of the new ideal circuit element, a
memristor. By definition, a memristor M relates the charge q and the magnetic
flux in a circuit, and complements a resistor R, a capacitor C, and an
inductor L as an ingredient of ideal electrical circuits. The properties of
these three elements and their circuits are a part of the standard curricula.
The existence of the memristor as the fourth ideal circuit element was
predicted in 1971 based on symmetry arguments, but was clearly experimentally
demonstrated just this year. We present the properties of a single memristor,
memristors in series and parallel, as well as ideal memristor-capacitor (MC),
memristor-inductor (ML), and memristor-capacitor-inductor (MCL) circuits. We
find that the memristor has hysteretic current-voltage characteristics. We show
that the ideal MC (ML) circuit undergoes non-exponential charge (current) decay
with two time-scales, and that by switching the polarity of the capacitor, an
ideal MCL circuit can be tuned from overdamped to underdamped. We present
simple models which show that these unusual properties are closely related to
the memristor's internal dynamics. This tutorial complements the pedagogy of
ideal circuit elements (R,C, and L) and the properties of their circuits.Comment: 22 pages, 12 figures, substantial text revisio
Critical currents and giant non-dissipative drag for superfluid electron-hole pairs in quantum Hall multilayers
Superfluid properties of electron-hole pairs in a quantum Hall four-layer
system are investigated. The system is considered as a solid state realization
of a two-component superfluid Bose gas with dipole-dipole interaction. One
superfluid component is formed in the top bilayer and the other component - in
the bottom one. We obtain the dispersion equation for the collective mode
spectrum and compute the critical parameters (the critical interlayer distance
and the critical currents) versus the filling factor. We find that the critical
currents of the components depend on each other. The maximum critical current
of a given component can be reached if the current of the other component is
equal to zero. The non-dissipative drag effect between the components is
studied. It is shown that in the system considered the drag factor is very
large. Under appropriate conditions it can be about 10 per sent, that is at
least in three order larder than one predicted for two-component atomic Bose
gases.Comment: 18 pages, 7 figure
Tree-level (pi, K)-amplitude and analyticity
We consider the tree-level amplitude, describing all 3 channels of the binary
(pi ,K)-reaction, as a meromorphic polynomially bounded function of 3 dependent
complex variables. Relying systematically on the Mittag-Leffler theorem, we
construct 3 convergent partial fraction expansions, each one being applied in
the corresponding domain. Noting, that the mutual intersections of those
domains are nonempty, we realize the analytical continuation. It is shown that
the necessary conditions to make such a continuation feasible, are the
following: 1) The only parameters completely determining the amplitude are the
on-shell couplings and masses; 2) These parameters are restricted by a certain
(infinite) system of bootstrap equations; 3) The full cross-symmetric amplitude
takes the typically dual form, the Pomeron contribution being taken into
account; 4)This latter contribution corresponds to a nonresonant background,
which, in turn, is expressed in terms of cross-channel resonances parameters.
It is demonstrated also, that the Chiral Symmetry provides a unique scale for
the mentioned parameters, the resonance saturation effect appearing as a direct
consequence of the above results
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