Comparison of pain relief among patients with chronic plantar fasciitis treated with intralesional platelet-rich plasma injection versus corticosteroid injection in a tertiary care centre in Kerala - a prospective study

Background: Aim of the study was to compare pain relief and functional outcome and between intralesional autologous platelet rich plasma injection (PRP) versus corticosteroid injection in the treatment of plantar, and fasciitis by using visual analogue score and American Orthopaedic Foot and Ankle Society (AOFAS) score. Methods: The sample size for the study was 30 patients attending Dr. Somervell Memorial CSI Medical College. Patients were divided into two groups (PRP versus steroid) of 15 each. The study follows a prospective observational design with follow up at 2 weeks, 2 months and 3 months post procedure. The functional outcome of patients in each group was assessed using the visual analog scale and AOFAS score. Results: Post-procedure, a significant decrease in VAS score was seen in patients treated with PRP injection (8.73 to 2.27) than those treated with Steroid injection (8.8 to 3.53). Also, there was a significant improvement in the AOFAS score from 72.73 to 88.67 while for those patients treated with steroid injection, the AOFAS score was comparatively low (65.87 to 82.2). Conclusions: Plantar fasciitis is a prevalent condition in our community, and many treatment options typically offer only temporary relief from symptoms. Intralesional PRP injection emerges as a dependable treatment method that fosters the healing process of the affected fascia, resulting in improved functional outcomes. Our study indicates that a singular administration of platelet-rich plasma injection for plantar fasciitis yields substantial pain relief compared to the local steroid injection

Effect of Nannochloropsis salina on the survival and growth of phyllosoma of the tropical spiny lobster, Panulirus homarus L. under laboratory conditions

The first successful advanced (stage VIII) larval development of the tropical spiny lobster, Panulirus homarus L. under laboratory culture has been achieved in a short span of 42 days. The culture treatments were maintained in two different systems, one with microalgae, Nannochloropsis salina (30-40 million cells/mL) and the other without microalgae. Phyllosoma attained stage VIII (5.25 mm) and stage V (3.36 mm) with an intermoult period of 4-6 and 5-9 days in the two systems respectively. The larvae moulted nine and six times in the microalgal and non-algal systems, respectively. Phyllosoma were fed with freshly hatched live Artemia salina nauplii (0.32 mm) for an initial period of 10 days, followed by juvenile Artemia (1.45 –1.54 mm) enriched with microalgae for the subsequent 15 days. Artemia enriched with commercial polyunsaturated fatty acid concentrate (DHA-Selco) was fed to the larvae for the rest of the culture period. Salinity and temperature were maintained at 33 ± 2 ppt and 28 ± 2 0C, respectively, while the pH recorded an optimum of 7.9 ± 0.5. The microalgal larval rearing system had lower bacterial load (total heterotrophic marine count, 1.0 X 103 CFU m L-1 and total Vibrio sp. count, 20 CFU/mL) compared to the nonmicroalgal system

Mouthpart morphology of phyllosoma of the tropical spiny lobster Panulirus homarus (Linnaeus, 1758)

Mouthpart morphology of Panulirus homarus phyllosoma larva was studied under scanning electron microscope in order to analyse the developmental changes during growth. Phyllosoma larvae have six pairs of mouthparts (mandibles, maxillule, maxilla, maxillipeds I, II, and III), labrum, and paired paragnaths. Increased length of second and third maxillipeds in late stage phyllosoma resulted in the increase of oral field, thus increasing its ability to catch prey. Labrum and paired paragnaths form a semienclosed oral chamber where mastication by the mandibles occurs. The improved threshing and tearing efficiency in late instars (stage VI-VIII) is facilitated by morphological changes in the mouthparts viz., increase in oral field, increased robustness and number of spinose setations of maxillule, and lengthy maxillipeds, indicating that the late instar larvae can process fleshier prey as compared to the early instar counterparts

Mixed ligand transition metal(II) complexes of Knoevenagel condensate-β-ketoesters with 1,2-diaminobenzene: Synthesis, structural characterization, electrochemical behaviour and antimicrobial study

693-699New Schiff base mixed ligand transition metal complexes of the composition, [ML(DB)2]Cl2, where M=Cu(II ), Ni(II), Co(ll) and Zn(II); L=Knoevenagel <span style="font-size:13.5pt;mso-bidi-font-size: 6.5pt;font-family:HiddenHorzOCR;mso-hansi-font-family:Arial;mso-bidi-font-family: HiddenHorzOCR;color:black">condensate- <span style="font-size:19.0pt; mso-bidi-font-size:12.0pt;font-family:Arial;mso-fareast-font-family:HiddenHorzOCR; color:black">β<span style="font-size:19.0pt;mso-bidi-font-size:12.0pt; font-family:HiddenHorzOCR;mso-hansi-font-family:Arial;mso-bidi-font-family: HiddenHorzOCR;color:black">-<span style="font-size:20.5pt;mso-bidi-font-size: 13.5pt;color:black">ketoesters <span style="font-size:15.0pt;mso-bidi-font-size: 8.0pt;font-family:Arial;color:black">derived from 1-hydroxybenzaldehyde and methyl ester of 3- oxobutanoic acid (HMOA)/ethyl ester of 3-oxobutanoic acid (HEOA)/N-phenyl-2-oxobutanamide (HPOB) and 1,2- diaminobenzene(DB), were synthesized. They were characterized on the basis of elemental analyses, magnetic susceptibility, FAB-mass, electronic absorption spectra, IR, 1H NMR, 13C NMR and ESR data. All the complexes exhibit octahedral geometry. Their magnetic susceptibility measurements and conductance data provide evidence for the monomeric and 1:2 electrolytic natures or the complexes. respectively. The electrochemical behaviour, the anodic and cathodic potential and the number of electron transfer were calculated using cyclic voltammogram. The antimicrobial activities of the ligand and its complexes have been studied by screening the compounds against various microorganisms (both Gram-positive and Gram-negative bacteria) and the results have been compared with the standard drug, ampicillin. The data showed that the complexes were highly active than that of the free ligand and the standard. </span

Synthesis and physico-chemical characterization of a new Mannich base, N( morpholinobenzyl)benzamide and its Cu(II), Co(II), Ni(II) and Zn(II) complexes

2357-2360A new Mannich base, N-(morpholinobenzyl)benzamide (MBB), formed by the condensation of morpholine, benzamide and benzaldehyde and its Cu(II), Co(II), Ni(II) and Zn(II) complexes have been synthesized. Their probable structures have been determined on the basis of their microanalytical, IR, UV-vis. 1H NMR, 13C NMR and FAB-mass spectral data. All the complexes exhibit square planar geometry. The monomeric and nonelectrolytic nature of the complexes are evidenced by their magnetic susceptibility and low conductance data. The electrochemical behaviour of the complexes in acetonitrile solution has been studied by cyclic voltammetric method. The biological activities of the ligand and its metal chelates against the bacteria E.coli, Staphylococcus aureus, Klebsiella pneumoniae, Salmonella typhi, Pseudomonas aeruginosa and Shigella flexuri are also reported. The complexes have higher activity than that of the free Mannich base and the control

Not Available

Not AvailableThe first successful advanced (stage VIII) larval development of the tropical spiny lobster, Panulirus homarus L. under laboratory culture has been achieved in a short span of 42 days. The culture treatments were maintained in two different systems, one with microalgae, Nannochloropsis salina (30-40 million cells/mL) and the other without microalgae. Phyllosoma attained stage VIII (5.25 mm) and stage V (3.36 mm) with an intermoult period of 4-6 and 5-9 days in the two systems respectively. The larvae moulted nine and six times in the microalgal and non-algal systems, respectively. Phyllosoma were fed with freshly hatched live Artemia salina nauplii (0.32 mm) for an initial period of 10 days, followed by juvenile Artemia (1.45 –1.54 mm) enriched with microalgae for the subsequent 15 days. Artemia enriched with commercial polyunsaturated fatty acid concentrate (DHA-Selco) was fed to the larvae for the rest of the culture period. Salinity and temperature were maintained at 33 ± 2 ppt and 28 ± 2 0C, respectively, while the pH recorded an optimum of 7.9 ± 0.5. The microalgal larval rearing system had lower bacterial load (total heterotrophic marine count, 1.0 X 103 CFU m L-1 and total Vibrio sp. count, 20 CFU/mL) compared to the nonmicroalgal system.Not Availabl

Not Available

Not AvailableMouthpart morphology of Panulirus homarus phyllosoma larva was studied under scanning electron microscope in order to analyse the developmental changes during growth. Phyllosoma larvae have six pairs of mouthparts (mandibles, maxillule, maxilla, maxillipeds I, II, and III), labrum, and paired paragnaths. Increased length of second and third maxillipeds in late stage phyllosoma resulted in the increase of oral field, thus increasing its ability to catch prey. Labrum and paired paragnaths form a semienclosed oral chamber where mastication by the mandibles occurs. The improved threshing and tearing efficiency in late instars (stage VI-VIII) is facilitated by morphological changes in the mouthparts viz., increase in oral field, increased robustness and number of spinose setations of maxillule, and lengthy maxillipeds, indicating that the late instar larvae can process fleshier prey as compared to the early instar counterparts.Not Availabl