2,040 research outputs found

    SNS Timing System

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    This poster describes the timing system being designed for Spallation Neutron Source being built at Oak Ridge National lab

    Video-Based Analyses of Parkinson's Disease Severity: A Brief Review

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    Remote and objective assessment of the motor symptoms of Parkinson's disease is an area of great interest particularly since the COVID-19 crisis emerged. In this paper, we focus on a) the challenges of assessing motor severity via videos and b) the use of emerging video-based Artificial Intelligence (AI)/Machine Learning techniques to quantitate human movement and its potential utility in assessing motor severity in patients with Parkinson's disease. While we conclude that video-based assessment may be an accessible and useful way of monitoring motor severity of Parkinson's disease, the potential of video-based AI to diagnose and quantify disease severity in the clinical context is dependent on research with large, diverse samples, and further validation using carefully considered performance standards

    Mobilizing Cause Supporters through Group-Based Interaction

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    This is the author accepted manuscript. The final version is available from Wiley via the DOI in this record.Collective action expresses group-based identities, formed by supporters seeking to further particular social causes. While the development of groups linked to action necessitates interaction among supporters, little research has examined how these groups form. Utilizing responses of supporters who participated in 1 of 29 action-planning sessions, this research presents an initial attempt to identify the ingredients important to this process. It shows that to the extent that the actions agreed on in the course of group interactions were seen as capable of making a difference (action efficacy), and worthy of public expression (action voice), supporters’ group-based identification was enhanced. This in turn increased their willingness to engage in collective action. Practical implications and avenues for future research to understand the mobilization process are discussed.Australian Research Counci

    Might it Be Possible to Assess Rigidity in PD Patients Remotely?

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    Identification of \u3ci\u3eBrucella\u3c/i\u3e spp. in feral swine (\u3ci\u3eSus scrofa\u3c/i\u3e) at abattoirs in Texas, USA

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    Various tissues, nasal swabs, urine and blood samples were collected from 376 feral swine at two federally inspected abattoirs in Texas during six separate sampling periods in 2015. Samples were tested for Brucella spp. by culture and serology. Brucella spp. were cultured from 13.0% of feral swine, and antibodies were detected in 9.8%. Only 32.7% of culture-positive feral swine were also antibody positive, and 43.2% of antibody-positive feral swine were culture positive. Approximately, the same number of males (14.0%) and females (12.1%) were culture positive, and slightly more males (10.5%) than females (8.7%) were antibody positive. Our results indicate that serology likely underestimates the prevalence of feral swine infected, and that those who come in contact with feral swine should be aware of the symptoms of infection with Brucella spp. to ensure prompt treatment

    High-Density Lipoprotein Cholesterol and Particle Concentrations, Carotid Atherosclerosis, and Coronary Events MESA (Multi-Ethnic Study of Atherosclerosis)

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    ObjectivesThe purpose of this study was to evaluate independent associations of high-density lipoprotein cholesterol (HDL-C) and particle (HDL-P) concentrations with carotid intima-media thickness (cIMT) and incident coronary heart disease (CHD).BackgroundHDL-C is inversely related to CHD, and also to triglycerides, low-density lipoprotein particles (LDL-P), and related metabolic risk. HDL-P associations with CHD may be partially independent of these factors.MethodsIn a multiethnic study of 5,598 men and women ages 45 to 84 years old, without baseline CHD, excluding subjects on lipid-lowering medications, triglycerides >400 mg/dl, or missing values, we evaluated associations of HDL-C and nuclear magnetic resonance spectroscopy-measured HDL-P with cIMT and incident CHD (myocardial infarction, CHD death, and angina, n = 227 events; mean 6.0 years follow-up). All models were adjusted for age, sex, ethnicity, hypertension, and smoking.ResultsHDL-C and HDL-P correlated with each other (ρ = 0.69) and LDL-P (ρ = −0.38, −0.25, respectively, p < 0.05 for all). For (1 SD) higher HDL-C (15 mg/dl) or HDL-P (6.64 ÎŒmol/l), cIMT differences were − 26.1 (95% confidence interval [CI]: −34.7 to −17.4) ÎŒm and −30.1 (95% CI: −38.8 to − 21.4) ÎŒm, and CHD hazard ratios were 0.74 (95% CI: 0.63 to 0.88) and 0.70 (95% CI: 0.59 to 0.82), respectively. Adjusted for each other and LDL-P, HDL-C was no longer associated with cIMT (2.3; 95% CI: − 9.5 to 14.2 ÎŒm) or CHD (0.97; 95% CI: 0.77 to 1.22), but HDL-P remained independently associated with cIMT (−22.2; 95% CI: − 33.8 to −10.6 ÎŒm) and CHD (0.75; 95% CI: 0.61 to 0.93). Interactions by sex, ethnicity, diabetes, and high-sensitivity C-reactive protein were not significant.ConclusionsAdjusting for each other and LDL-P substantially attenuated associations of HDL-C, but not HDL-P, with cIMT and CHD. Potential confounding by related lipids or lipoproteins should be carefully considered when evaluating HDL-related risk

    Impact of dialect use on a basic component of learning to read

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    Can some black-white differences in reading achievement be traced to differences in language background? Many African American children speak a dialect that differs from the mainstream dialect emphasized in school. We examined how use of alternative dialects affects decoding, an important component of early reading and marker of reading development. Behavioral data show that use of the alternative pronunciations of words in different dialects affects reading aloud in developing readers, with larger effects for children who use more African American English. Mechanisms underlying this effect were explored with a computational model, investigating factors affecting reading acquisition. The results indicate that the achievement gap may be due in part to differences in task complexity: children whose home and school dialects differ are at greater risk for reading difficulties because tasks such as learning to decode are more complex for them

    "Driven to distraction?" Children's experiences of car travel

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    This is an Author's Accepted Manuscript of an article published in volume, 4, issue 1, pages 59-76 in Mobilities 2009. Copyright @ 2009 Taylor & Francis, available online at: http://www.tandfonline.com/doi/abs/10.1080/17450100802657962.Cars have become increasingly significant features in the lives of many children and adults in the UK and elsewhere. Whilst there is a growing body of research considering how adults experience automobility, that is the increasingly central role of cars within societies, there has been little equivalent research exploring children's perspectives. Drawing upon a variety of methods including personal diaries, photographs, in‐depth interviews and surveys amongst schools within Buckinghamshire and North London, the paper contributes to filling this gap in existing research through exploring how cars are not only journey spaces for children, but are also sites for play, relaxation, homework, companionship, technology and the consumption of commodities. Using a Foucauldian analysis of power, insights into wider familial processes relating to mobility are provided by exploring how cars are sites of conflicting power relations between parents and children. The paper also explores how children's everyday experiences of cars were framed by wider sets of power relations, including car corporations which design and manufacture these spaces, and the role of capital which commodifies everyday activities in cars. In doing so, the paper challenges existing research on automobility for only focusing upon adults' experiences of cars and begins to theorise a more inclusive account of automobility which incorporates children and young people
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