47 research outputs found
Positron-neutrino correlation in the 0^+ \to 0^+ decay of ^{32}Ar
The positron-neutrino correlation in the decay of
Ar was measured at ISOLDE by analyzing the effect of lepton recoil on
the shape of the narrow proton group following the superallowed decay. Our
result is consistent with the Standard Model prediction. For vanishing Fierz
interference we find , which yields improved
constraints on scalar weak interactions
Sharpening Low-Energy, Standard-Model Tests via Correlation Coefficients in Neutron Beta-Decay
The correlation coefficients a, A, and B in neutron beta-decay are
proportional to the ratio of the axial-vector to vector weak coupling
constants, g_A/g_V, to leading recoil order. With the advent of the next
generation of neutron decay experiments, the recoil-order corrections to these
expressions become experimentally accessible, admitting a plurality of Standard
Model (SM) tests. The measurement of both a and A, e.g., allows one to test the
conserved-vector-current (CVC) hypothesis and to search for second-class
currents (SCC) independently. The anticipated precision of these measurements
suggests that the bounds on CVC violation and SCC from studies of nuclear
beta-decay can be qualitatively bettered. Departures from SM expectations can
be interpreted as evidence for non-V-A currents.Comment: 4 pages, REVTeX, intro. broadened, typos fixed, to appear in PR
The angular distribution of the reaction
The reaction is very important for low-energy
( MeV) antineutrino experiments. In this paper we calculate
the positron angular distribution, which at low energies is slightly backward.
We show that weak magnetism and recoil corrections have a large effect on the
angular distribution, making it isotropic at about 15 MeV and slightly forward
at higher energies. We also show that the behavior of the cross section and the
angular distribution can be well-understood analytically for MeV by calculating to , where is the nucleon mass. The
correct angular distribution is useful for separating events from other reactions and detector backgrounds, as well as for
possible localization of the source (e.g., a supernova) direction. We comment
on how similar corrections appear for the lepton angular distributions in the
deuteron breakup reactions and . Finally, in the reaction , the
angular distribution of the outgoing neutrons is strongly forward-peaked,
leading to a measurable separation in positron and neutron detection points,
also potentially useful for rejecting backgrounds or locating the source
direction.Comment: 10 pages, including 5 figure
MicroRNA Expression Profiling Identifies Activated B Cell Status in Chronic Lymphocytic Leukemia Cells
Chronic lymphocytic leukemia (CLL) is thought to be a disease of resting lymphocytes. However, recent data suggest that CLL cells may more closely resemble activated B cells. Using microRNA (miRNA) expression profiling of highly-enriched CLL cells from 38 patients and 9 untransformed B cells from normal donors before acute CpG activation and 5 matched B cells after acute CpG activation, we demonstrate an activated B cell status for CLL. Gene set enrichment analysis (GSEA) identified statistically-significant similarities in miRNA expression between activated B cells and CLL cells including upregulation of miR-34a, miR-155, and miR-342-3p and downregulation of miR-103, miR-181a and miR-181b. Additionally, decreased levels of two CLL signature miRNAs miR-29c and miR-223 are associated with ZAP70+ and IgVH unmutated status and with shorter time to first therapy. These data indicate an activated B cell status for CLL cells and suggest that the direction of change of individual miRNAs may predict clinical course in CLL
The neutron and its role in cosmology and particle physics
Experiments with cold and ultracold neutrons have reached a level of
precision such that problems far beyond the scale of the present Standard Model
of particle physics become accessible to experimental investigation. Due to the
close links between particle physics and cosmology, these studies also permit a
deep look into the very first instances of our universe. First addressed in
this article, both in theory and experiment, is the problem of baryogenesis ...
The question how baryogenesis could have happened is open to experimental
tests, and it turns out that this problem can be curbed by the very stringent
limits on an electric dipole moment of the neutron, a quantity that also has
deep implications for particle physics. Then we discuss the recent spectacular
observation of neutron quantization in the earth's gravitational field and of
resonance transitions between such gravitational energy states. These
measurements, together with new evaluations of neutron scattering data, set new
constraints on deviations from Newton's gravitational law at the picometer
scale. Such deviations are predicted in modern theories with extra-dimensions
that propose unification of the Planck scale with the scale of the Standard
Model ... Another main topic is the weak-interaction parameters in various
fields of physics and astrophysics that must all be derived from measured
neutron decay data. Up to now, about 10 different neutron decay observables
have been measured, much more than needed in the electroweak Standard Model.
This allows various precise tests for new physics beyond the Standard Model,
competing with or surpassing similar tests at high-energy. The review ends with
a discussion of neutron and nuclear data required in the synthesis of the
elements during the "first three minutes" and later on in stellar
nucleosynthesis.Comment: 91 pages, 30 figures, accepted by Reviews of Modern Physic
A coincidence-type ion-electron converter detector with low background for low-energy protons
Primary structure of ICAM-1 demonstrates interaction between members of the immunoglobulin and integrin supergene families.
Intercellular adhesion molecule 1 (ICAM-1) is a 90 kd inducible surface glycoprotein that promotes adhesion in immunological and inflammatory reactions. ICAM-1 is a ligand of lymphocyte function-associated antigen-1 (LFA-1), an alpha beta complex that is a member of the integrin family of cell-cell and cell-matrix receptors. ICAM-1 is encoded by an inducible 3.3 kb mRNA. The amino acid sequence specifies an integral membrane protein with an extracellular domain of 453 residues containing five immunoglobulin-like domains. Highest homology is found with neural cell adhesion molecule (NCAM) and myelin-associated glycoprotein (MAG), which also contain five Ig-like domains. NCAM and MAG are nervous system adhesion molecules, but unlike ICAM-1, NCAM is homophilic. The ICAM-1 and LFA-1 interaction is heterophilic and unusual in that it is between members of the immunoglobulin and intergrin families. Unlike other integrin ligands, ICAM-1 does not contain an RGD sequence