175 research outputs found
A Novel Approach for Hull Hydrodynamic Surrogate Models with Convolutional Neural Networks (CNNs)
Use of pulmonary function test demographic data to identify high-risk patients for lung cancer screening
Lung Cancer is the primary cause of cancer-related death in the United States. We have recognized a need for novel methods of identification and consideration of enrollment into a lung cancer screening program for those at the highest risk of lung cancer. Our primary goal was to determine if pulmonary function test (PFT) demographic data would be useful in identifying patients for lung cancer screening. We retrospectively reviewed PFTs performed at Lahey Hospital & Medical Center (LHMC) January 2012 through January 2013 and found that of patients identified as high risk of lung cancer, 89% had passed through our PFT lab but had not yet been screened. Investigation into the barriers of lung cancer screening to better understand how to increase appropriate enrollment then followed. A total of 3098 PFTs were reviewed from January 2012 through January 2013 and 634 patients (20%) were identified as high risk for lung cancer. Of 634 patients, 70 (11%) were already in the LHMC lung cancer screening program. The remaining 564 patients (89%) were not enrolled, and of these, it was found that 292 patients identified as high risk for lung cancer represented missed opportunities for screening. The remaining 272 patients were appropriately not screened with the three most common reasons being prior imaging with positive finding, lung cancer within five years, and provider discussed but scan not yet performed. Appropriate enrollment in a lung cancer screening program may be increased with the careful use of demographic data obtained from a PFT lab.
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Single event upset tests of a RISC-based fault-tolerant computer
The project successfully demonstrated that dual lock-step comparison of commercial RISC processors is a viable fault-tolerant approach to handling SEU in space environment. The fault tolerant approach on orbit error rate was 38 times less than the single processor error rate. The random nature of the upsets and appearance in critical code section show it is essential to incorporate both hardware and software in the design and operation of fault-tolerant computers
Defects of Tensioned Membrane Structures (TMS) In Tropics
The wide use of tensioned membrane structures (TMS) becomes prominent in many designs because of its aesthetic, ergonomic, and economical nature. Recently, TMS has been applied in the tropics with success, yet defects specific to this region have received little attention. Through a questionnaire survey of 890 uses and technicians of TMS in three different areas in Malaysia, this study identified the most frequently occurring TMS defects in the tropics, such as "deterioration of roof coatings", "corrosion or fatigue in fixings", "fungal decay, mould growth, and dirt in membrane", "corrosion in anchor cables", and "degradation of fabrics". These defects are quite different from those in other climatic zones. The top five causes of TMS defects in the tropics are weather, aging, design, construction/installation, and material selection. However, only "corrosion or fatigue in fixings" is a significant predictor for "deterioration of roof coatings". While this is not a causal effect, a practical implication is that TMS maintenance workers do not have to climb up to the roof to check the deterioration in coating but only need to predict the deterioration through the corrosion levels of the fixings. Further, seven countermeasures for TMS in tropic are recommended. This study is the first comprehensive study examining tensioned membrane structure defects in the tropics
Serendipitous discovery and X-ray structure of a human phosphate binding apolipoprotein
Early childhood pedagogies: spaces for young children to flourish
This paper introduces the Special Issue of Early Child Development and Care focused on Early Childhood Pedagogy. It opens by considering past and present discourses concerning early childhood pedagogy, and focus is given to established philosophical underpinnings in the field and their translation to contemporary guidance, alongside research and policy. It is argued that early childhood pedagogy is a contested, complex and diverse space, yet these factors are entirely appropriate for supporting young children to flourish as valued individuals in different contexts. Building on this argument, it is posited that it may be more appropriate to discuss early childhood pedagogies rather than early childhood pedagogy. The paper goes on to critique a range of established early childhood pedagogies, before introducing 18 papers from across the world that make exciting new contributions to the discourse. It is intended that this collection will inspire new debates and fresh endeavours concerning early childhood pedagogies
Quantitative assessment of parkinsonian bradykinesia based on an inertial measurement unit
Applying an extended theoretical framework for data collection mode to health services research
<p>Abstract</p> <p>Background</p> <p>Over the last 30 years options for collecting self-reported data in health surveys and questionnaires have increased with technological advances. However, mode of data collection such as face-to-face interview or telephone interview can affect how individuals respond to questionnaires. This paper adapts a framework for understanding mode effects on response quality and applies it to a health research context.</p> <p>Discussion</p> <p>Data collection modes are distinguished by key features (whether the survey is self- or interviewer-administered, whether or not it is conducted by telephone, whether or not it is computerised, whether it is presented visually or aurally). Psychological appraisal of the survey request will initially entail factors such as the cognitive burden upon the respondent as well as more general considerations about participation. Subsequent psychological response processes will further determine how features of the data collection mode impact upon the quality of response provided. Additional antecedent factors which may further interact with the response generation process are also discussed. These include features of the construct being measured such as sensitivity, and of the respondent themselves (e.g. their socio-demographic characteristics). How features of this framework relate to health research is illustrated by example.</p> <p>Summary</p> <p>Mode features can affect response quality. Much existing evidence has a broad social sciences research base but is of importance to health research. Approaches to managing mode feature effects are discussed. Greater consideration must be given to how features of different data collection approaches affect response from participants in studies. Study reports should better clarify such features rather than rely upon global descriptions of data collection mode.</p
Aerothermoelastic Analysis of Functionally Graded Plates Using Generalized Differential Quadrature Method
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