Quenched QCD with domain wall fermions

We report on simulations of quenched QCD using domain wall fermions, where we focus on basic questions about the formalism and its ability to produce expected low energy hadronic physics for light quarks. The work reported here is on quenched $8^3 \times 32$ lattices at $\beta = 5.7$ and 5.85, using values for the length of the fifth dimension between 10 and 48. We report results for parameter choices which lead to the desired number of flavors, a study of undamped modes in the extra dimension and hadron masses.Comment: Contribution to Lattice '98. Presented by R. Mawhinney. 3 pages, 3 figure

The domain wall fermion chiral condensate in quenched QCD

We examine the chiral limit of domain wall fermions in quenched QCD. One expects that in a quenched simulation, exact fermion zero modes will give a divergent, 1/m behavior in the chiral condensate for sufficiently small valence quark masses. Unlike other fermion formulations, domain wall fermions clearly demonstrate this behavior.Comment: LATTICE98(spectrum), G. R. Fleming presented talk, 5 pages, 3 figures, corrected typos in printed versio

Dynamical QCD thermodynamics with domain wall fermions

We present results from numerical simulations of full, two flavor QCD thermodynamics at N_t=4 with domain wall fermions. For the first time a numerical simulation of the full QCD phase transition displays a low temperature phase with spontaneous chiral symmetry breaking but intact flavor symmetry and a high temperature phase with the full SU(2) x SU(2) chiral flavor symmetry.Comment: LATTICE98(hightemp

Bub1 mediates cell death in response to chromosome missegregation and acts to suppress spontaneous tumorigenesis

The physiological role of the mitotic checkpoint protein Bub1 is unknown. To study this role, we generated a series of mutant mice with a gradient of reduced Bub1 expression using wild-type, hypomorphic, and knockout alleles. Bub1 hypomorphic mice are viable, fertile, and overtly normal despite weakened mitotic checkpoint activity and high percentages of aneuploid cells. Bub1 haploinsufficient mice, which have a milder reduction in Bub1 protein than Bub1 hypomorphic mice, also exhibit reduced checkpoint activity and increased aneuploidy, but to a lesser extent. Although cells from Bub1 hypomorphic and haploinsufficient mice have similar rates of chromosome missegregation, cell death after an aberrant separation decreases dramatically with declining Bub1 levels. Importantly, Bub1 hypomorphic mice are highly susceptible to spontaneous tumors, whereas Bub1 haploinsufficient mice are not. These findings demonstrate that loss of Bub1 below a critical threshold drives spontaneous tumorigenesis and suggest that in addition to ensuring proper chromosome segregation, Bub1 is important for mediating cell death when chromosomes missegregate

The split cube in a cage: Bulk negative-index material for infrared applications

Abstract We propose the split cube in a cage (SCiC) design for application in producing a bulk metamaterial. Applying realistic material data for thin silver films, we observe an immediate convergence of the effective parameters obtained with a number of layers towards the bulk properties. Results are obtained by two different numerical techniques: the Fourier modal method and the finite integrals method, thus ensuring their validity. The SCiC exhibits a refractive index of −0.6 for frequencies close to the telecommunication bands. The fast convergence of effective parameters allows consideration of the SCiC as a bulk (effectively homogeneous) negative-index metamaterial even for a single layer. The bulk-like nature together with the cubic symmetry of the unit cell make the SCiC a promising candidate for potential applications at telecommunication frequencies