167 research outputs found
Implementacija digitalnog generatora obojenog ĹĄuma bez mnoĹžila
Colored noise can be generated by filtering of the white noise. It is a simple task. However, it becomes challenging if high operating speed of the generator is required. The realization of digital filter generally requires one multiplication per coefficient. Therefore, a high operating speed is achieved only with the cost of several generalpurpose multipliers. In this paper, a multiplierless realization of the colored noise generator is proposed. It is based on the filtering of 1-bit random signal by a finite impulse response filter. The design of the generator is described and its implementation is considered. Furthermore, an application is described in which the proposed generator is used in mitigation of undesired effects caused by nonlinearities in an analog to digital converter.Obojeni ĹĄum moĹže se generirati filtriranjem bijelog ĹĄuma. To je jednostavan postupak. MeÄutim, on postaje izazovan ako se od generatora traĹži velika brzina rada. Realizacija digitalnog filtra u pravilu zahtijeva jedno mnoĹženje po koeficijentu. Zato se velika brzina rada moĹže postiÄi samo uz cijenu veÄeg broja mnoĹžila opÄe namjene. U ovom radu predloĹžena je realizacija generatora obojenog ĹĄuma koja ne sadrĹži mnoĹžila. Ona se temelji se na filtraciji 1-bitnog sluÄajnog signala pomoÄu filtra s konaÄnim impulsnim odzivom. Opisano je projektiranje generatora te je razmotrena njegova implementacija. Nadalje, opisana je primjena u kojoj je predloĹženi generator iskoriĹĄten za smanjivanje utjecaja nelinearnosti u analogno digitalnom pretvorniku
Electromagnetic fields at the sea bottom induced by a line of immersed electric dipoles
Cryopyrin-Associated Periodic Syndrome: An Update on Diagnosis and Treatment Response
Cryopyrin-associated periodic syndrome (CAPS) is a rare hereditary inflammatory disorder encompassing a continuum of three phenotypes: familial cold autoinflammatory syndrome, Muckle-Wells syndrome, and neonatal-onset multisystem inflammatory disease. Distinguishing features include cutaneous, neurological, ophthalmologic, and rheumatologic manifestations. CAPS results from a gain-of-function mutation of the NLRP3 gene coding for cryopyrin, which forms intracellular protein complexes known as inflammasomes. Defects of the inflammasomes lead to overproduction of interleukin-1, resulting in inflammatory symptoms seen in CAPS. Diagnosis is often delayed and requires a thorough review of clinical symptoms. Remarkable advances in our understanding of the genetics and the molecular pathway that is responsible for the clinical phenotype of CAPS has led to the development of effective treatments. It also has become clear that the NLRP3 inflammasome plays a critical role in innate immune defense and therefore has wider implications for other inflammatory disease states
What Is Stochastic Resonance? Definitions, Misconceptions, Debates, and Its Relevance to Biology
Stochastic resonance is said to be observed when increases in levels of unpredictable fluctuationsâe.g., random noiseâcause an increase in a metric of the quality of signal transmission or detection performance, rather than a decrease. This counterintuitive effect relies on system nonlinearities and on some parameter ranges being âsuboptimalâ. Stochastic resonance has been observed, quantified, and described in a plethora of physical and biological systems, including neurons. Being a topic of widespread multidisciplinary interest, the definition of stochastic resonance has evolved significantly over the last decade or so, leading to a number of debates, misunderstandings, and controversies. Perhaps the most important debate is whether the brain has evolved to utilize random noise in vivo, as part of the âneural codeâ. Surprisingly, this debate has been for the most part ignored by neuroscientists, despite much indirect evidence of a positive role for noise in the brain. We explore some of the reasons for this and argue why it would be more surprising if the brain did not exploit randomness provided by noiseâvia stochastic resonance or otherwiseâthan if it did. We also challenge neuroscientists and biologists, both computational and experimental, to embrace a very broad definition of stochastic resonance in terms of signal-processing ânoise benefitsâ, and to devise experiments aimed at verifying that random variability can play a functional role in the brain, nervous system, or other areas of biology
Resistivity structure across Itoigawa-Shizuoka tectonic line and its implications for concentrated deformation
Relation of the graphite and fluid bearing conducting dikes to the tectonics and seismicity (Review on the Transdanubian crustal conductivity anomaly)
A physical, genetic and functional sequence assembly of the barley genome
Barley (Hordeum vulgare L.) is among the world's earliest domesticated and most important crop plants. It is diploid with a large haploid genome of 5.1 gigabases (Gb). Here we present an integrated and ordered physical, genetic and functional sequence resource that describes the barley gene-space in a structured whole-genome context. We developed a physical map of 4.98 Gb, with more than 3.90 Gb anchored to a high-resolution genetic map. Projecting a deep whole-genome shotgun assembly, complementary DNA and deep RNA sequence data onto this framework supports 79,379 transcript clusters, including 26,159 'high-confidence' genes with homology support from other plant genomes. Abundant alternative splicing, premature termination codons and novel transcriptionally active regions suggest that post-transcriptional processing forms an important regulatory layer. Survey sequences from diverse accessions reveal a landscape of extensive single-nucleotide variation. Our data provide a platform for both genome-assisted research and enabling contemporary crop improvement
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