The denitridation of nitrides of iron, cobalt and rhenium under hydrogen

The denitridation behaviour of binary iron, cobalt and rehnium nitrides under H2 /Ar has been investigated. The iron nitride was found to lose over 70 % of its as prepared nitrogen content at 400 °C. The cobalt nitride was completely denitrided at 250 °C. Rhenium nitride lost close to 90 % of its nitrogen at 350 °C. In addition, Co-Re4 prepared by ammonolyis was investigated, whilst only traces of NH<sub>3</sub> were lost from this material under H<sub>2</sub>/Ar at 400 °C, with H<sub>2</sub>/N2 it proved to be an active ambient pressure ammonia synthesis catalyst in accordance with previous literature

Hot methane line lists for exoplanet and brown dwarf atmospheres

We present comprehensive experimental line lists of methane (CH4) at high temperatures obtained by recording Fourier transform infrared emission spectra. Calibrated line lists are presented for the temperatures 300 - 1400 degC at twelve 100 degC intervals spanning the 960 - 5000 cm-1 (2.0 - 10.4 microns) region of the infrared. This range encompasses the dyad, pentad and octad regions, i.e., all fundamental vibrational modes along with a number of combination, overtone and hot bands. Using our CH4 spectra, we have estimated empirical lower state energies (Elow in cm-1) and our values have been incorporated into the line lists along with line positions (cm-1) and calibrated line intensities (S' in cm molecule-1). We expect our hot CH4 line lists to find direct application in the modeling of planetary atmospheres and brown dwarfs.Comment: Supplementary material is provided via the Astrophysical Journal referenc

The Velocity Dispersion Profile of the Remote Dwarf Spheroidal Galaxy Leo I: A Tidal Hit and Run?

(abridged) We present kinematic results for a sample of 387 stars located near Leo I based on spectra obtained with the MMT's Hectochelle spectrograph near the MgI/Mgb lines. We estimate the mean velocity error of our sample to be 2.4 km/s, with a systematic error of < 1 km/s. We produce a final sample of 328 Leo I red giant members, from which we measure a mean heliocentric radial velocity of 282.9 +/- 0.5 km/s, and a mean radial velocity dispersion of 9.2 +/- 0.4 km/s for Leo I. The dispersion profile of Leo I is flat out to beyond its classical `tidal' radius. We fit the profile to a variety of equilibrium dynamical models and can strongly rule out models where mass follows light. Two-component Sersic+NFW models with tangentially anisotropic velocity distributions fit the dispersion profile well, with isotropic models ruled out at a 95% confidence level. The mass and V-band mass-to-light ratio of Leo I estimated from equilibrium models are in the ranges 5-7 x 10^7 M_sun and 9-14 (solar units), respectively, out to 1 kpc from the galaxy center. Leo I members located outside a `break radius' (about 400 arcsec = 500 pc) exhibit significant velocity anisotropy, whereas stars interior appear to have isotropic kinematics. We propose the break radius represents the location of the tidal radius of Leo I at perigalacticon of a highly elliptical orbit. Our scenario can account for the complex star formation history of Leo I, the presence of population segregation within the galaxy, and Leo I's large outward velocity from the Milky Way. The lack of extended tidal arms in Leo I suggests the galaxy has experienced only one perigalactic passage with the Milky Way, implying that Leo I may have been injected into its present orbit by a third body a few Gyr before perigalacticon.Comment: ApJ accepted, 23 figures, access paper as a pdf file at http://www.astro.lsa.umich.edu/~mmateo/research.htm

Improved Searches for HI in Three Dwarf Spheroidal Galaxies

Previous searches for HI in our Galaxy's dwarf spheroidal companions have not been complete enough to settle the question of whether or not these galaxies have HI, especially in their outer parts. We present VLA observations of three dwarf spheroidals: Fornax, Leo II, and Draco, all of which have known stellar velocities. The new data show no HI emission or absorption. Column density limits in emission are 4--7 x 10^18 atoms/cm^2 in the centers of the galaxies. The importance of the new observations is that they cover larger areas than previous searches and they are less plagued by confusion with foreground (Galactic) HI. The apparent absence of neutral gas in the Fornax dwarf spheroidal is especially puzzling because recent photometry shows evidence of stars only 10^8 years old. We discuss whether the VLA observations could have missed significant amounts of HI.Comment: 20 pages, 7 figures; to appear in the Astronomical Journa

Low-energy electron scattering by tetrahydrofuran

Cross sections for elastic scattering of low-energy electrons by tetrahydrofuran, a prototype for the furanose ring found in the backbone of DNA, have been measured and calculated over a wide energy range, with an emphasis on energies below 6 eV, where previous data are scarce. The measurements employ a thin-aperture version of the relative-flow method, while the calculations employ the Schwinger multichannel method with an extensive treatment of polarization effects. Comparisons with earlier results, both experimental and theoretical, are presented and discussed. A proper accounting for the strong permanent electric dipole of tetrahydrofuran is found to be essential to obtaining reliable cross sections, especially at energies below 5 eV

Collisions of low-energy electrons with isopropanol

We report measured and calculated cross sections for elastic scattering of low-energy electrons by isopropanol (propan-2-ol). The experimental data were obtained using the relative flow technique with helium as the standard gas and a thin aperture as the collimating target gas source, which permits use of this method without the restrictions imposed by the relative flow pressure conditions on helium and the unknown gas. The differential cross sections were measured at energies of 1.5, 2, 3, 5, 6, 8, 10, 15, 20, and 30 eV and for scattering angles from 10∘ to 130∘. The cross sections were computed over the same energy range employing the Schwinger multichannel method in the static-exchange plus polarization approximation. Agreement between theory and experiment is very good. The present data are compared with previously calculated and measured results for n-propanol, the other isomer of C_3H_7OH. Although the integral and momentum transfer cross sections for the isomers are very similar, the differential cross sections show a strong isomeric effect: In contrast to the f-wave behavior seen in scattering by n-propanol, d-wave behavior is observed in the cross sections of isopropanol. These results corroborate our previous observations in electron collisions with isomers of C_4H_9OH

A Dynamical Fossil in the Ursa Minor Dwarf Spheroidal Galaxy

The nearby Ursa Minor dwarf spheroidal (UMi dSph) is one of the most dark matter dominated galaxies known, with a central mass to light ratio roughly equal to 70. Somewhat anomalously, it appears to contain morphological substructure in the form of a second peak in the stellar number density. It is often argued that this substructure must be transient because it could not survive for the > 10 Gyr age of the system, given the crossing time implied by UMi's 8.8 km/s internal velocity dispersion. In this paper, however, we present evidence that the substructure has a cold kinematical signature, and argue that UMi's clumpiness could indeed be a primordial artefact. Using numerical simulations, we demonstrate that substructure is incompatible with the cusped dark matter haloes predicted by the prevailing Cold Dark Matter (CDM) paradigm, but is consistent with an unbound stellar cluster sloshing back and forth within the nearly harmonic potential of a cored dark matter halo. Thus CDM appears to disagree with observation at the least massive, most dark matter dominated end of the galaxy mass spectrum.Comment: Astrophysical Journal (Letters), in pres

Voluntary Counselling, HIV Testing and Adjunctive Cotrimoxazole Reduces Mortality in Tuberculosis Patients in Thyolo, Malawi.

OBJECTIVES: To assess the feasibility and effectiveness of voluntary counselling, HIV testing and adjunctive cotrimoxazole in reducing mortality in a cohort of tuberculosis (TB) patients registered under routine programme conditions in a rural district of Malawi. DESIGN: 'Before' and 'after' cohort study using historical controls. METHODS: Between 1 July 1999 and 30 June 2000 all TB patients were started on standardized anti-TB treatment, and offered voluntary counselling and HIV testing (VCT). Those found to be HIV-positive were offered cotrimoxazole at a dose of 480 mg twice daily, provided there were no contraindications. Side-effects were monitored clinically. End-of-treatment outcomes in this cohort (intervention group) were compared with a cohort registered between 1 July 1998 and 30 June 1999 in whom VCT and cotrimoxazole was not offered (control group). FINDINGS: A total of 1986 patients was registered in the study: 1061 in the intervention group and 925 in the control cohort. In the intervention group, 1019 (96%) patients were counselled pre-test, 964 (91%) underwent HIV testing and 938 (88%) were counselled post-test. The overall HIV-seroprevalence rate was 77%. A total of 693 patients were given cotrimoxazole of whom 14 (2%) manifested minor dermatological reactions. The adjusted relative risk of death in the intervention group compared with the control group was 0.81 (P < 0.001). The number needed to treat with VCT and adjunctive cotrimoxazole to prevent one death during anti-TB treatment was 12.5. INTERPRETATION: This study shows that VCT and adjunctive cotrimoxazole is feasible, safe and reduces mortality rates in TB patients under routine programme conditions

Reduced tubulin tyrosination as an early marker of mercury toxicity in differentiating N2a cells

The aims of this work were to compare the effects of methyl mercury chloride and Thimerosal on neurite/process outgrowth and microtubule proteins in differentiating mouse N2a neuroblastoma and rat C6 glioma cells. Exposure for 4 h to sublethal concentrations of both compounds inhibited neurite outgrowth to a similar extent in both cells lines compared to controls. In the case of N2a cells, this inhibitory effect by both compounds was associated with a fall in the reactivity of western blots of cell extracts with monoclonal antibody T1A2, which recognises C-terminally tyrosinated α-tubulin. By contrast, reactivity with monoclonal antibody B512 (which recognises total α-tubulin) was unaffected at the same time point. These findings suggest that decreased tubulin tyrosination represents a neuron-specific early marker of mercury toxicity associated with impaired neurite outgrowth