2,390 research outputs found
MANAGING NUTRIENT LOSSES: SOME EMPIRICAL RESULTS ON THE POTENTIAL WATER QUALITY EFFECTS
Over-application of manure on cropland can cause water quality degradation. This paper reports a modeling approach for assessing tradeoffs among manure storage and handling systems as they relate to the nutrient loadings in cropland runoff, including nitrate losses to groundwater. The CREAMS simulation model provided estimates of nutrient losses. A linear optimization model was used to determine the income-nutrient loss tradeoffs. Six-month storage was profitable for farmers with average-size dairy herds, but compared to daily spreading caused increased nitrate leaching through the soil to groundwater resources. Twelve-month storage systems decreased farm profitability while decreasing the total nitrogen losses from farm fields.Environmental Economics and Policy,
On a Service-Oriented Approach for an Engineering Knowledge Desktop
Increasingly, manufacturing companies are shifting their focus from selling products to providing services. As a result, when designing new products, engineers must increasingly consider the life cycle costs in addition to any design requirements. To identify possible areas of concern, designers are required to consult existing maintenance information from identical products. However, in a large engineering company, the amount of information available is significant and in wide range of formats. This paper presents a prototype knowledge desktop suitable for the design engineer. The Engineering Knowledge Desktop analyses and suggests relevant information from ontologically marked-up heterogeneous web resources. It is designed using a Service-Oriented Architecture, with an ontology to mediate between Web Services. It has been delivered to the user community for evaluation
Data Mining to Support Engineering Design Decision
The design and maintenance of an aero-engine generates a significant amount of documentation. When designing new engines, engineers must obtain knowledge gained from maintenance of existing engines to identify possible areas of concern. Firstly, this paper investigate the use of advanced business intelligence tenchniques to solve the problem of knowledge transfer from maintenance to design of aeroengines. Based on data availability and quality, various models were deployed. An association model was used to uncover hidden trends among parts involved in maintenance events. Classification techniques comprising of various algorithms was employed to determine severity of events. Causes of high severity events that lead to major financial loss was traced with the help of summarization techniques. Secondly this paper compares and evaluates the business intelligence approach to solve the problem of knowledge transfer with solutions available from the Semantic Web. The results obtained provide a compelling need to have data mining support on RDF/OWL-based warehoused data
Fresh street: the development and feasibility of a place-based, subsidy for fresh fruit and vegetables
Background
Many UK communities experience food insecurity, and consume diets high in energy-dense, nutrient poor, processed foods and low in fruit and vegetables (FV). We explored a novel area-based approach to promote FV consumption and healthy eating in one such community.
Methods
We developed a weekly subsidy scheme for fresh FV with key local stakeholders in an area of socioeconomic deprivation in Northern England. The scheme (Fresh Street) offered five £1 vouchers to every household, regardless of income or household type. Vouchers were redeemable with local suppliers of fresh FV (not supermarkets). The feasibility of the scheme was assessed in four streets using rapid ethnographic assessment and voucher redemption information.
Results
Local councillors and public health teams were supportive of the scheme. Most eligible households joined the scheme (n = 80/97, 83%), and 89.3% (17 849/19 982) of vouchers issued were redeemed. Householders reported that the scheme made them think about what they were eating, and prompted them to buy and eat more FV.
Conclusions
This feasibility study reported high levels of acceptance for a place-based, household-level weekly FV subsidy scheme. Further research is required to evaluate the effectiveness of this approach to creating healthy diets, eating behaviours and food systems
Darwin Meets Einstein: LISA Data Analysis Using Genetic Algorithms
This work presents the first application of the method of Genetic Algorithms
(GAs) to data analysis for the Laser Interferometer Space Antenna (LISA). In
the low frequency regime of the LISA band there are expected to be tens of
thousands galactic binary systems that will be emitting gravitational waves
detectable by LISA. The challenge of parameter extraction of such a large
number of sources in the LISA data stream requires a search method that can
efficiently explore the large parameter spaces involved. As signals of many of
these sources will overlap, a global search method is desired. GAs represent
such a global search method for parameter extraction of multiple overlapping
sources in the LISA data stream. We find that GAs are able to correctly extract
source parameters for overlapping sources. Several optimizations of a basic GA
are presented with results derived from applications of the GA searches to
simulated LISA data.Comment: 8 pages, 12 figure
Nicotinamide mononucleotide adenylyltransferase promotes hypoxic survival by activating the mitochondrial unfolded protein response
Gain-of-function mutations in the mouse nicotinamide mononucleotide adenylyltransferase type 1 (Nmnat1) produce two remarkable phenotypes: protection against traumatic axonal degeneration and reduced hypoxic brain injury. Despite intensive efforts, the mechanism of Nmnat1 cytoprotection remains elusive. To develop a new model to define this mechanism, we heterologously expressed a mouse Nmnat1 non-nuclear-localized gain-of-function mutant gene (m-nonN-Nmnat1) in the nematode Caenorhabditis elegans and show that it provides protection from both hypoxia-induced animal death and taxol-induced axonal pathology. Additionally, we find that m-nonN-Nmnat1 significantly lengthens C. elegans lifespan. Using the hypoxia-protective phenotype in C. elegans, we performed a candidate screen for genetic suppressors of m-nonN-Nmnat1 cytoprotection. Loss of function in two genes, haf-1 and dve-1, encoding mitochondrial unfolded protein response (mitoUPR) factors were identified as suppressors. M-nonN-Nmnat1 induced a transcriptional reporter of the mitoUPR gene hsp-6 and provided protection from the mitochondrial proteostasis toxin ethidium bromide. M-nonN-Nmnat1 was also protective against axonal degeneration in C. elegans induced by the chemotherapy drug taxol. Taxol markedly reduced basal expression of a mitoUPR reporter; the expression was restored by m-nonN-Nmnat1. Taken together, these data implicate the mitoUPR as a mechanism whereby Nmnat1 protects from hypoxic and axonal injury
DNase I-hypersensitive sites surround the mouse acetylcholine receptor delta-subunit gene.
A Solution to the Galactic Foreground Problem for LISA
Low frequency gravitational wave detectors, such as the Laser Interferometer
Space Antenna (LISA), will have to contend with large foregrounds produced by
millions of compact galactic binaries in our galaxy. While these galactic
signals are interesting in their own right, the unresolved component can
obscure other sources. The science yield for the LISA mission can be improved
if the brighter and more isolated foreground sources can be identified and
regressed from the data. Since the signals overlap with one another we are
faced with a ``cocktail party'' problem of picking out individual conversations
in a crowded room. Here we present and implement an end-to-end solution to the
galactic foreground problem that is able to resolve tens of thousands of
sources from across the LISA band. Our algorithm employs a variant of the
Markov Chain Monte Carlo (MCMC) method, which we call the Blocked Annealed
Metropolis-Hastings (BAM) algorithm. Following a description of the algorithm
and its implementation, we give several examples ranging from searches for a
single source to searches for hundreds of overlapping sources. Our examples
include data sets from the first round of Mock LISA Data Challenges.Comment: 19 pages, 27 figure
Observed Limits on Charge Exchange Contributions to the Diffuse X-ray Background
We present a high resolution spectrum of the diffuse X-ray background from
0.1 to 1 keV for a ~1 region of the sky centered at l=90, b=+60 using a
36-pixel array of microcalorimeters flown on a sounding rocket. With an energy
resolution of 11 eV FWHM below 1 keV, the spectrum's observed line ratios help
separate charge exchange contributions originating within the heliosphere from
thermal emission of hot gas in the interstellar medium. The X-ray sensitivity
below 1 keV was reduced by about a factor of four from contamination that
occurred early in the flight, limiting the significance of the results. The
observed centroid of helium-like O VII is 568+2-3 eV at 90% confidence. Since
the centroid expected for thermal emission is 568.4 eV while for charge
exchange is 564.2 eV, thermal emission appears to dominate for this line
complex, consistent with much of the high-latitude O VII emission originating
in 2-3 x 10^6 K gas in the Galactic halo. On the other hand, the observed ratio
of C VI Ly gamma to Ly alpha is 0.3+-0.2. The expected ratios are 0.04 for
thermal emission and 0.24 for charge exchange, indicating that charge exchange
must contribute strongly to this line and therefore potentially to the rest of
the ROSAT R12 band usually associated with 10^6 K emission from the Local Hot
Bubble. The limited statistics of this experiment and systematic uncertainties
due to the contamination require only >32% thermal emission for O VII and >20%
from charge exchange for C VI at the 90% confidence level. An experimental gold
coating on the silicon substrate of the array greatly reduced extraneous
signals induced on nearby pixels from cosmic rays passing through the
substrate, reducing the triggered event rate by a factor of 15 from a previous
flight of the instrument.Comment: 14 pages, 7 figures, to be published in Ap
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