222 research outputs found
Four-dimensional polymer collapse II: Pseudo-First-Order Transition in Interacting Self-avoiding Walks
In earlier work we provided the first evidence that the collapse, or
coil-globule, transition of an isolated polymer in solution can be seen in a
four-dimensional model. Here we investigate, via Monte Carlo simulations, the
canonical lattice model of polymer collapse, namely interacting self-avoiding
walks, to show that it not only has a distinct collapse transition at finite
temperature but that for any finite polymer length this collapse has many
characteristics of a rounded first-order phase transition. However, we also
show that there exists a `-point' where the polymer behaves in a simple
Gaussian manner (which is a critical state), to which these finite-size
transition temperatures approach as the polymer length is increased. The
resolution of these seemingly incompatible conclusions involves the argument
that the first-order-like rounded transition is scaled away in the
thermodynamic limit to leave a mean-field second-order transition. Essentially
this happens because the finite-size \emph{shift} of the transition is
asymptotically much larger than the \emph{width} of the pseudo-transition and
the latent heat decays to zero (algebraically) with polymer length. This
scenario can be inferred from the application of the theory of Lifshitz,
Grosberg and Khokhlov (based upon the framework of Lifshitz) to four
dimensions: the conclusions of which were written down some time ago by
Khokhlov. In fact it is precisely above the upper critical dimension, which is
3 for this problem, that the theory of Lifshitz may be quantitatively
applicable to polymer collapse.Comment: 30 pages, 14 figures included in tex
IUPAC-NIST solubility data series. 81. Hydrocarbons with water and seawater - Revised and updated. Part 8. C9 hydrocarbons with water
The mutual solubility and related liquid-liquid equilibria of C9 hydrocarbons with water are exhaustively and critically reviewed. Reports of the experimental determination of solubility in 18 chemically distinct binary systems that appeared in the primary literature prior to the end of 2002 are compiled. For 8 systems, sufficient data are available to allow critical evaluation. All data are expressed as mass percent and mole fraction, as well as the originally reported units. In addition to the standard evaluation criteria used throughout the Solubility Date Series, a new method based on the evaluation of the all experimental data for a given homologous series of aliphatic and aromatic hydrocarbons was used
IUPAC-NIST solubility data series. 81. Hydrocarbons with water and seawater-revised and updated. Part 5. C7 hydrocarbons with water and heavy water
The mutual solubility and related liquid-liquid equilibria of C7 hydrocarbons with water and heavy water are exhaustively and critically reviewed. Reports of experimental determination of solubility in 23 chemically distinct binary systems that appeared in the primary literature prior to end of 2002 are compiled. For 9 systems sufficient data are available to allow critical evaluation. All data are expressed as mass percent and mole fraction as well as the originally reported units. In addition to the standard evaluation criteria used throughout the Solubility Data Series, a new method based on the evaluation of the all experimental data for a given homologous series of aliphatic and aromatic hydrocarbons was used
Exact Results for Hamiltonian Walks from the Solution of the Fully Packed Loop Model on the Honeycomb Lattice
We derive the nested Bethe Ansatz solution of the fully packed O() loop
model on the honeycomb lattice. From this solution we derive the bulk free
energy per site along with the central charge and geometric scaling dimensions
describing the critical behaviour. In the limit we obtain the exact
compact exponents and for Hamiltonian walks, along with
the exact value for the connective constant
(entropy). Although having sets of scaling dimensions in common, our results
indicate that Hamiltonian walks on the honeycomb and Manhattan lattices lie in
different universality classes.Comment: 12 pages, RevTeX, 3 figures supplied on request, ANU preprint
MRR-050-9
Scaling of Self-Avoiding Walks in High Dimensions
We examine self-avoiding walks in dimensions 4 to 8 using high-precision
Monte-Carlo simulations up to length N=16384, providing the first such results
in dimensions on which we concentrate our analysis. We analyse the
scaling behaviour of the partition function and the statistics of
nearest-neighbour contacts, as well as the average geometric size of the walks,
and compare our results to -expansions and to excellent rigorous bounds
that exist. In particular, we obtain precise values for the connective
constants, , , ,
and give a revised estimate of . All of
these are by at least one order of magnitude more accurate than those
previously given (from other approaches in and all approaches in ).
Our results are consistent with most theoretical predictions, though in
we find clear evidence of anomalous -corrections for the scaling of
the geometric size of the walks, which we understand as a non-analytic
correction to scaling of the general form (not present in pure
Gaussian random walks).Comment: 14 pages, 2 figure
CAR Co-Operates With Integrins to Promote Lung Cancer Cell Adhesion and Invasion.
The coxsackie and adenovirus receptor (CAR) is a member of the junctional adhesion molecule (JAM) family of adhesion receptors and is localised to epithelial cell tight and adherens junctions. CAR has been shown to be highly expressed in lung cancer where it is proposed to promote tumor growth and regulate epithelial mesenchymal transition (EMT), however the potential role of CAR in lung cancer metastasis remains poorly understood. To better understand the role of this receptor in tumor progression, we manipulated CAR expression in both epithelial-like and mesenchymal-like lung cancer cells. In both cases, CAR overexpression promoted tumor growth in vivo in immunocompetent mice and increased cell adhesion in the lung after intravenous injection without altering the EMT properties of each cell line. Overexpression of WTCAR resulted in increased invasion in 3D models and enhanced β1 integrin activity in both cell lines, and this was dependent on phosphorylation of the CAR cytoplasmic tail. Furthermore, phosphorylation of CAR was enhanced by substrate stiffness in vitro, and CAR expression increased at the boundary of solid tumors in vivo. Moreover, CAR formed a complex with the focal adhesion proteins Src, Focal Adhesion Kinase (FAK) and paxillin and promoted activation of the Guanine Triphosphate (GTP)-ase Ras-related Protein 1 (Rap1), which in turn mediated enhanced integrin activation. Taken together, our data demonstrate that CAR contributes to lung cancer metastasis via promotion of cell-matrix adhesion, providing new insight into co-operation between cell-cell and cell-matrix proteins that regulate different steps of tumorigenesis
A note on graded Yang-Baxter solutions as braid-monoid invariants
We construct two solutions of the graded Yang-Baxter equation by
using the algebraic braid-monoid approach. The factorizable S-matrix
interpretation of these solutions is also discussed.Comment: 7 pages, UFSCARF-TH-94-1
Stretched Polymers in a Poor Solvent
Stretched polymers with attractive interaction are studied in two and three
dimensions. They are described by biased self-avoiding random walks with
nearest neighbour attraction. The bias corresponds to opposite forces applied
to the first and last monomers. We show that both in and a phase
transition occurs as this force is increased beyond a critical value, where the
polymer changes from a collapsed globule to a stretched configuration. This
transition is second order in and first order in . For we
predict the transition point quantitatively from properties of the unstretched
polymer. This is not possible in , but even there we can estimate the
transition point precisely, and we can study the scaling at temperatures
slightly below the collapse temperature of the unstretched polymer. We find
very large finite size corrections which would make very difficult the estimate
of the transition point from straightforward simulations.Comment: 10 pages, 16 figure
Anomalous polymer collapse winding angle distributions
In two dimensions polymer collapse has been shown to be complex with multiple
low temperature states and multi-critical points. Recently, strong numerical
evidence has been provided for a long-standing prediction of universal scaling
of winding angle distributions, where simulations of interacting self-avoiding
walks show that the winding angle distribution for N-step walks is compatible
with the theoretical prediction of a Gaussian with a variance growing
asymptotically as C log N . Here we extend this work by considering interacting
self-avoiding trails which are believed to be a model representative of some of
the more complex behaviour. We provide robust evidence that, while the high
temperature swollen state of this model has a winding angle distribution that
is also Gaussian, this breaks down at the polymer collapse point and at low
temperatures. Moreover, we provide some evidence that the distributions are
well modelled by stretched/compressed exponentials, in contradistinction to the
behaviour found in interacting self-avoiding walks.Comment: 9 pages, 7 figure
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