97 research outputs found

    Implications of conservation equations for the determination of absolute velocities

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    The consequences of assuming that density is conserved in the problem of determining absolute velocities are investigated. Two questions are considered: (i) the constraints that the density must satisfy to be compatible with the assumed geostrophic and hydrostatic dynamics and (ii) whether and to what extent the indeterminacy in this dynamics is removed by this additional assumption

    Enzyme kinetics for a two-step enzymic reaction with comparable initial enzyme-substrate ratios

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    We extend the validity of the quasi-steady state assumption for a model double intermediate enzyme-substrate reaction to include the case where the ratio of initial enzyme to substrate concentration is not necessarily small. Simple analytical solutions are obtained when the reaction rates and the initial substrate concentration satisfy a certain condition. These analytical solutions compare favourably with numerical solutions of the full system of differential equations describing the reaction. Experimental methods are suggested which might permit the application of the quasi-steady state assumption to reactions where it may not have been obviously applicable before

    Toward a theory of repeat purchase drivers for consumer services

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    The marketing discipline’s knowledge about the drivers of service customers’ repeat purchase behavior is highly fragmented. This research attempts to overcome that fragmented state of knowledge by making major advances toward a theory of repeat purchase drivers for consumer services. Drawing on means–end theory, the authors develop a hierarchical classification scheme that organizes repeat purchase drivers into an integrative and comprehensive framework. They then identify drivers on the basis of 188 face-to-face laddering interviews in two countries (USA and Germany) and assess the drivers’ importance and interrelations through a national probability sample survey of 618 service customers. In addition to presenting an exhaustive and coherent set of hierarchical repeat-purchase drivers, the authors provide theoretical explanations for how and why drivers relate to one another and to repeat purchase behavior. This research also tests the boundary conditions of the proposed framework by accounting for different service types. In addition to its theoretical contribution, the framework provides companies with specific information about how to manage long-term customer relationships successfully

    Improving resolution of public health surveillance for human Salmonella enterica serovar Typhimurium infection: 3 years of prospective multiple-locus variable-number tandem-repeat analysis (MLVA)

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    <p>Abstract</p> <p>Background</p> <p>Prospective typing of <it>Salmonella enterica </it>serovar Typhimurium (STM) by multiple-locus variable-number tandem-repeat analysis (MLVA) can assist in identifying clusters of STM cases that might otherwise have gone unrecognised, as well as sources of sporadic and outbreak cases. This paper describes the dynamics of human STM infection in a prospective study of STM MLVA typing for public health surveillance.</p> <p>Methods</p> <p>During a three-year period between August 2007 and September 2010 all confirmed STM isolates were fingerprinted using MLVA as part of the New South Wales (NSW) state public health surveillance program.</p> <p>Results</p> <p>A total of 4,920 STM isolates were typed and a subset of 4,377 human isolates was included in the analysis. The STM spectrum was dominated by a small number of phage types, including DT170 (44.6% of all isolates), DT135 (13.9%), DT9 (10.8%), DT44 (4.5%) and DT126 (4.5%). There was a difference in the discriminatory power of MLVA types within endemic phage types: Simpson's index of diversity ranged from 0.109 and 0.113 for DTs 9 and 135 to 0.172 and 0.269 for DTs 170 and 44, respectively. 66 distinct STM clusters were observed ranging in size from 5 to 180 cases and in duration from 4 weeks to 25 weeks. 43 clusters had novel MLVA types and 23 represented recurrences of previously recorded MLVA types. The diversity of the STM population remained relatively constant over time. The gradual increase in the number of STM cases during the study was not related to significant changes in the number of clusters or their size. 667 different MLVA types or patterns were observed.</p> <p>Conclusions</p> <p>Prospective MLVA typing of STM allows the detection of community outbreaks and demonstrates the sustained level of STM diversity that accompanies the increasing incidence of human STM infections. The monitoring of novel and persistent MLVA types offers a new benchmark for STM surveillance.</p> <p>A part of this study was presented at the MEEGID × (Molecular Epidemiology and Evolutionary Genetics of Infectious Diseases) Conference, 3-5 November 2010, Amsterdam, The Netherlands</p

    Bi-orthogonality relationships involving porous media

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    Bi-orthogonality relationships are established for a vertically heterogeneous porous media in contact with a fluid, a solid, a second porous medium, and a free surface. Fraser's bi-orthgonality relation for propagation of Rayleigh-Lamb modes in a plate with traction free eurfaces is shown to be a special case of the bi-orthogonality relations derived herein in which the medium can be thought of as a porous slab with zero porosity

    A proof of two conjectures related to the Erdos-Debrunner inequality

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    In this papere we prove two conjectures proposed by Janous on an extension to the p-th power-mean of the Erdos-Debrunner inequality relating the areas of the four subtriangles formed by connecting three arbitrary points on the sides of a given triangle

    On the number of segments needed in a piecewise linear approximation

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    Jour. of Computational and Applied Mathematics. Volume 234, Issue 2, 15 May 2010, pp. 437-446.This publication is a work of the U.S. Government as defined in Title 17, United States Code, Section 101. As such, it is in the public domain, and under the provisions of Title 17, United States Code, Section 105, may not be copyrighted.The introduction of high-speed circuits to realize an arithmetic function f as a piecewise linear approximation has created a need to understand how the number of segments depends on the interval a is greater or equal to x which is greater or equal to b and the desired approximation error e..
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