14 research outputs found
The mechanism of spin and charge separation in one dimensional quantum antiferromagnets
We reconsider the problem of separation of spin and charge in one dimensional
quantum antiferromagnets. We show that spin and charge separation in one
dimensional strongly correlated systems cannot be described by the slave boson
or fermion representation within any perturbative treatment of the interactions
between the slave holons and slave spinons. The constraint of single occupancy
must be implemented exactly. As a result the slave fermions and bosons are not
part of the physical spectrum. Instead, the excitations which carry the
separate spin and charge quantum numbers are solitons. To prove this {\it
no-go} result, it is sufficient to study the pure spinon sector in the slave
boson representation. We start with a short-range RVB spin liquid mean-field
theory for the frustrated antiferromagnetic spin- chain. We derive
an effective theory for the fluctuations of the Affleck-Marston and Anderson
order parameters. We show how to recover the phase diagram as a function of the
frustration by treating the fluctuations non-perturbatively.Comment: 53 pages; Revtex 3.
Electrospun Polyurethane Fibers for Absorption of Volatile Organic Compounds from Air
Electrospun polyurethane fibers for removal of volatile organic compounds (VOC) from air with rapid VOC absorption and desorption have been developed. Polyurethanes based on 4,4-methylenebis(phenylisocyanate) (MDI) and aliphatic isophorone diisocyanate as the hard segments and butanediol and tetramethylene glycol as the soft segments were electrospun from their solutions in N,N-dimethylformamide to form micrometer-sized fibers. Although activated carbon possessed a many-fold higher surface area than the polyurethane fiber meshes, the sorption capacity of the polyurethane fibers was found to be similar to that of activated carbon specifically designed for vapor adsorption. Furthermore, in contrast to VOC sorption on activated carbon, where complete regeneration of the adsorbent was not possible, the polyurethane fibers demonstrated a completely reversible absorption and desorption, with desorption obtained by a simple purging with nitrogen at room temperature. The fibers possessed a high affinity toward toluene and chloroform, but aliphatic hexane lacked the necessary strong attractive interactions with the polyurethane chains and therefore was less strongly absorbed. The selectivity of the polyurethane fibers toward different vapors, along with the ease of regeneration, makes them attractive materials for VOC filtration.Boeing CompanyNetherlands Organisation for Scientific Research (NWO) (Talent Scholarship
Fusion of the erythropoietin receptor and the Friend spleen focus-forming virus gp55 glycoprotein transforms a factor-dependent hematopoietic cell line
Transformation properties of the E2a-Pbx1 chimeric oncoprotein: fusion with E2a is essential, but the Pbx1 homeodomain is dispensable
A European multi-centre evaluation of detection and typing methods for human enteroviruses and parechoviruses using RNA transcripts
Polymerase chain reaction (PCR) detection has become the gold standard for diagnosis and typing of enterovirus (EV) and human parechovirus (HPeV) infections. Its effectiveness depends critically on using the appropriate sample types and high assay sensitivity as viral loads in cerebrospinal fluid samples from meningitis and sepsis clinical presentation can be extremely low. This study evaluated the sensitivity and specificity of currently used commercial and inâhouse diagnostic and typing assays. Accurately quantified RNA transcript controls were distributed to 27 diagnostic and 12 reference laboratories in 17 European countries for blinded testing. Transcripts represented the four human EV species (EVâA71, echovirus 30, coxsackie A virus 21, and EVâD68), HPeV3, and specificity controls. Reported results from 48 inâhouse and 15 commercial assays showed 98% detection frequencies of high copy (1000 RNA copies/5â”L) transcripts. Inâhouse assays showed significantly greater detection frequencies of the low copy (10 copies/5â”L) EV and HPeV transcripts (81% and 86%, respectively) compared with commercial assays (56%, 50%; Pâ=â7âĂâ10â5). EVâspecific PCRs showed low crossâreactivity with human rhinovirus C (3 of 42 tests) and infrequent positivity in the negative control (2 of 63 tests). Most or all high copy EV and HPeV controls were successfully typed (88%, 100%) by reference laboratories, but showed reduced effectiveness for low copy controls (41%, 67%). Stabilized RNA transcripts provide an effective, logistically simple and inexpensive reagent for evaluation of diagnostic assay performance. The study provides reassurance of the performance of the many inâhouse assay formats used across Europe. However, it identified often substantially reduced sensitivities of commercial assays often used as pointâofâcare tests
Testing whether independent treatment groups have equal medians
L-statistics, Harrell-Davis estimator, bootstrap, kernel density estimates, smoothing,