Interferometry with Photon-Subtracted Thermal Light

We propose and implement a quantum procedure for enhancing the sensitivity with which one can determine the phase shift experienced by a weak light beam possessing thermal statistics in passing through an interferometer. Our procedure entails subtracting exactly one (which can be generalized to m) photons from the light field exiting an interferometer containing a phase-shifting element in one of its arms. As a consequence of the process of photon subtraction, and somewhat surprisingly, the mean photon number and signal-to-noise ratio of the resulting light field are thereby increased, leading to enhanced interferometry. This method can be used to increase measurement sensitivity in a variety of practical applications, including that of forming the image of an object illuminated only by weak thermal light

Emitter-Metasurface Interface for Manipulating Emission Characteristics of Quantum Defects

We demonstrate a chip-scale quantum emitter-metamaterial device that emits highly directional photons. Our device opens the door for quantum imaging of yveak sources by adding photon(s) to manipulate the photon statistics for improved signal-to-noise ratio

Emitter-Metasurface Interface for Manipulating Emission Characteristics of Quantum Defects

We demonstrate a chip-scale quantum emitter-metamaterial device that emits highly directional photons. Our device opens the door for quantum imaging of yveak sources by adding photon(s) to manipulate the photon statistics for improved signal-to-noise ratio

emiT: an apparatus to test time reversal invariance in polarized neutron decay

We describe an apparatus used to measure the triple-correlation term (\D \hat{\sigma}_n\cdot p_e\times p_\nu) in the beta-decay of polarized neutrons. The \D-coefficient is sensitive to possible violations of time reversal invariance. The detector has an octagonal symmetry that optimizes electron-proton coincidence rates and reduces systematic effects. A beam of longitudinally polarized cold neutrons passes through the detector chamber, where a small fraction beta-decay. The final-state protons are accelerated and focused onto arrays of cooled semiconductor diodes, while the coincident electrons are detected using panels of plastic scintillator. Details regarding the design and performance of the proton detectors, beta detectors and the electronics used in the data collection system are presented. The neutron beam characteristics, the spin-transport magnetic fields, and polarization measurements are also described.Comment: 15 pages, 13 figure

Quantum-enhanced interferometry with weak thermal light

We propose and implement a procedure for enhancing the sensitivity with which one can determine the phase shift experienced by a thermal light beam possessing on average fewer than four photons in passing through an interferometer. Our procedure entails subtracting exactly one (which can be generalized to m) photon from the light field exiting an interferometer containing a phase-shifting element in one of its arms. As a consequence of the process of photon subtraction, the mean photon number and signal-to-noise ratio (SNR) of the resulting light field are increased, leading to an enhancement of the SNR of the interferometric signal for that fraction of the incoming data that leads to photon subtraction

Unjamming overcomes kinetic and proliferation arrest in terminally differentiated cells and promotes collective motility of carcinoma

During wound repair, branching morphogenesis and carcinoma dissemination, cellular rearrangements are fostered by a solid-to-liquid transition, known as unjamming. The biomolecular machinery behind unjamming and its pathophysiological relevance remain, however, unclear. Here, we study unjamming in a variety of normal and tumorigenic epithelial two-dimensional (2D) and 3D collectives. Biologically, the increased level of the small GTPase RAB5A sparks unjamming by promoting non-clathrin-dependent internalization of epidermal growth factor receptor that leads to hyperactivation of the kinase ERK1/2 and phosphorylation of the actin nucleator WAVE2. This cascade triggers collective motility effects with striking biophysical consequences. Specifically, unjamming in tumour spheroids is accompanied by persistent and coordinated rotations that progressively remodel the extracellular matrix, while simultaneously fluidizing cells at the periphery. This concurrent action results in collective invasion, supporting the concept that the endo-ERK1/2 pathway is a physicochemical switch to initiate collective invasion and dissemination of otherwise jammed carcinoma