Heterogeneous Dynamics of Coupled Vibrations

Frequency-dependent dynamics of coupled stretch vibrations of a water molecule are revealed by 2D IR correlation spectroscopy. These are caused by non-Gaussian fluctuations of the environment around the individual OH stretch vibrations

Ultrafast exciton transport in organic nanotubes

The dynamics of exciton transport between the inner and outer walls of double-layer cylindrical aggregates is measured. Downhill transport is fast (275 A) and excitation intensity independent. Uphill transport is much slower (3.5 ps), but this rate increases when the excitation density is raised. This suggests that exciton-exciton annihilation is involved

Ultrafast energy and electron transfer in donor-acceptor molecules for photovoltaics

The rapid advancement in fullerene chemistry allows the covalent functionalization of C60 with electron donors. Various C60-based donor-acceptor dyads have been synthesized and studied to gain insight in the intramolecular photophysical processes, like energy and electron transfer. Although these dyads can serve as a model compounds for the conjugated photovoltaic cells, only a few examples have been reported with these C60-based dyads. Apart from being well-defined model systems for photophysical characterization, the covalent linkage between donor, and acceptor in these molecular arrays provides a simple method to achieve control over the phase segregation in donor-acceptor networks. We investigate an oligo(phenylene vinylene)fullerene dyad with 4 phenyl groups (C60-OPV4) in solvents of different polarity using femtosecond pump-probe spectroscopy. We find that photoexcitation of the oligomer leads first to an intramolecular energy transfer to the fullerene, while an electron transfer is a secondary process, only allowed in polar solvents.

Supplementary Material for: Clonal Megakaryocyte Dysplasia with Isolated Thrombocytosis Is a Distinct Myeloproliferative Neoplasm Phenotype

Introduction: About 15% of people with a myeloproliferative neoplasm (MPN) are identified as MPN, unclassifiable using the 2016 WHO classification. Methods: We tested whether persons with platelet concentration ≥450 × 10E+9/L, bone marrow megakaryocyte morphology typical of prefibrotic/early myelofibrosis (pre-MF), and no minor criteria of pre-MF should be classified as a distinct MPN subtype, clonal megakaryocyte dysplasia with isolated thrombocytosis (CMD-IT). Results: 139 subjects meet these criteria who we compared with primary myelofibrosis (PMF) including 402 with pre-MF and 521 with overt myelofibrosis. CMD-IT subjects were more likely female and younger. They had lower frequencies of JAK2V617F compared with persons with PMF (55% vs. 70%; p CALR mutations (37% vs. 17%; p JAK2V617F susceptibility, JAK2 46/1 (35% vs. 47%; p = 0.021), and VEGFA rs3025039 (12% vs. 17%; p = 0.030). Subjects with CMD-IT had lower incidences of thrombotic events compared with those with pre-MF (9.7% vs. 26%; p p Conclusion: Our data indicate CMD-IT is a distinct MPN subtype and should be included in the classification of myeloid neoplasms