111 research outputs found

    Tunneling giant magnetoresistance in coevaporated Fex(SiO)1−x thin films

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    International audienceFe x (SiO) 1x thin films, with volume fraction x ranging from 0.04 to 0.6, have been prepared by coevaporation. Magnetization, resistivity, and magnetoresistance measurements show that the behavior of this composite is metallic like for x0.35. For 0.2x0.27, the confrontation of all measurements prove the existence of a tunneling giant magnetoresistance between ferromagnetic grains at T300 K, where the mean radius of the grains is estimated to be about 1 nm

    Magnetic and transport properties of evaporated Fe/SiO multilayers

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    International audienceFe/SiO discontinuous multilayers consisting of layers of Fe particles embedded in an insulating SiO matrix have been prepared by evaporation. Their structural, magnetic, and transport properties have been studied as a function of Fe and SiO thickness. For small iron thicknesses, magnetic measurements show a superparamagnetic behavior above a blocking temperature determined by field-cooled and zero-field-cooled magnetization curves. Negative magnetoresistance due to spin-dependent tunneling has been observed in both current-in-plane and current-perpendicular-to-the-plane geometries. For the smaller iron thickness 5 Å͒, a Coulomb blockade effect is observed at low temperature together with an increase of the magnetoresistance

    Enhanced magnetoresistance by monoatomic roughness in epitaxial Fe/MgO/Fe tunnel junctions

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    Under the terms of the Creative Commons Attribution License 3.0 (CC-BY).-- et al.Interfacial effects on spin and symmetry filtering in single-crystal Fe(001)/MgO/Fe magnetic tunnel junctions are investigated with the insertion of a Fe monoatomic step at the bottom MgO interface. After annealing, the atomically flat bottom electrode is covered by a fractional part of a Fe monoatomic layer resulting in two-dimensional Fe islands that are separated for low coverages and percolated above around half a monolayer. The magnetotransport properties of the junctions are studied as a function of this Fe sublayer coverage that is varied from 0 to 1 monolayer. Surprisingly, the magnetoresistance ratio exhibits a maximum for a coverage around half a monolayer. Tunneling spectroscopy experiments performed at low temperature allow relating this result to the decrease of the contribution of the interfacial resonance state to the conductance of the junction.C.T. acknowledges the following projects: SPINCHAT (ANR-07-BLAN-341), POS CCE ID.574, code SMIS-CSNR 12467, and the Exploratory Research Project, “SPINTAIL” PN-II-ID-PCE-2012-4-0315, No. 23/29.08.2013.Peer Reviewe

    A monolithic micro-tensile tester for investigating silica micromechanics, fabricated and fully operated using a femtosecond laser Citation for published version (APA)

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    . (2014). A monolithic micro-tensile tester for investigating silica micromechanics, fabricated and fully operated using a femtosecond laser

    Antiferromagnetic ordering in a 90 K copper oxide superconductor

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    Using elastic neutron scattering, we evidence a commensurate antiferromagnetic Cu(2) order (AF) in the superconducting (SC) high-Tc\rm T_c cuprate YBa2(Cu1yCoy)3O7+δ\rm YBa_2(Cu_{1-y}Co_y)_3O_{7+\delta} (y=0.013, Tc\rm T_c=93 K). As in the Co-free system, the spin excitation spectrum is dominated by a magnetic resonance peak at 41 meV but with a reduced spectral weight. The substitution of Co thus leads to a state where AF and SC cohabit showing that the CuO2_2 plane is a highly antiferromagnetically polarizable medium even for a sample where Tc_c remains optimum.Comment: 3 figure

    Serendipitous alkylation of a Plk1 ligand uncovers a new binding channel

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    We obtained unanticipated synthetic byproducts from alkylation of the δ[superscript 1] nitrogen (N3) of the histidine imidazole ring of the polo-like kinase-1 (Plk1) polo-box domain (PBD)-binding peptide PLHSpT. For the highest-affinity byproduct, bearing a C[subscript 6]H[subscript 5](CH[subscript 2])[subscript 8]– group, a Plk1 PBD cocrystal structure revealed a new binding channel that had previously been occluded. An N-terminal PEGylated version of this peptide containing a hydrolytically stable phosphothreonyl residue (pT) bound the Plk1 PBD with affinity equal to that of the non-PEGylated parent but showed markedly less interaction with the PBDs of the two closely related proteins Plk2 and Plk3. Treatment of cultured cells with this PEGylated peptide resulted in delocalization of Plk1 from centrosomes and kinetochores and in chromosome misalignment that effectively induced mitotic block and apoptotic cell death. This work provides insights that might advance efforts to develop Plk1 PBD-binding inhibitors as potential Plk1-specific anticancer agents.National Institutes of Health (U.S.) (Grant GM60594)National Institutes of Health (U.S.) (Grant GM68762)National Institutes of Health (U.S.) (Grant CA112967

    Ultrafast laser micro-nano structuring of transparent materials with high aspect ratio

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    Ultrafast lasers are ideal tools to process transparent materials because they spatially confine the deposition of laser energy within the material's bulk via nonlinear photoionization processes. Nonlinear propagation and filamentation were initially regarded as deleterious effects. But in the last decade, they turned out to be benefits to control energy deposition over long distances. These effects create very high aspect ratio structures which have found a number of important applications, particularly for glass separation with non-ablative techniques. This chapter reviews the developments of in-volume ultrafast laser processing of transparent materials. We discuss the basic physics of the processes, characterization means, filamentation of Gaussian and Bessel beams and provide an overview of present applications

    Functional outcomes in symptomatic versus asymptomatic patients undergoing incisional hernia repair: Replacing one problem with another? A prospective cohort study in 1312 patients

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    Background: Incisional hernias can be associated with pain or discomfort. Surgical repair especially mesh reinforcement, may likewise induce pain. The primary objective was to assess the incidence of pain after hernia repair in patients with and without pre-operative pain or discomfort. The secondary objectives were to determine the preferred mesh type, mesh location and surgical technique in minimizing postoperative pain or discomfort. Materials and methods: A registry-based prospective cohort study was performed, including patients undergoing incisional hernia repair between September 2011 and May 2019. Patients with a minimum follow-up of 3–6 months were included. The incidence of hernia related pain and discomfort was recorded perioperatively. Results: A total of 1312 patients were included. Pre-operatively, 1091 (83%) patients reported pain or discomfort. After hernia repair, 961 (73%) patients did not report pain or discomfort (mean follow-up = 11.1 months). Of the pre-operative asymptomatic patients (n = 221), 44 (20%, moderate or severe pain: n = 14, 32%) reported pain or discomfort after mean follow-up of 10.5 months. Of those patients initially reporting pain or discomfort (n = 1091), 307 (28%, moderate or severe pain: n = 80, 26%) still reported pain or discomfort after a mean follow-up of 11.3 months postoperatively. Conclusion: In symptomatic incisional hernia patients, hernia related complaints may be resolved in the majority of cases undergoing surgical repair. In asymptomatic incisional hernia patients, pain or discomfort may be induced in a considerable number of patients due to surgical repair and one should be aware if this postoperative complication
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