Superparamagnetic particles in ZSM-5-type ferrisilicates

As-synthesized, low iron content, ferrisilicates of ZSM-5-type contain well-separated Fe(III) ions in a tetrahedral environment and display paramagnetic behavior. After hydrothermal treatment, the iron ions are partially extracted from the framework, generating nanosize iron oxide or oxyhydroxide ferrimagnetic particles. This process has been studied by transmission electron microscopy (TEM), Mossbauer spectroscopy, magnetic ac susceptibility (chi(ac)), and field dependent magnetization, on samples containing up to 6.7 wt. % Fe. The experiments evidence the growth of nonaggregated particles, with a typical size around 3 nm, presumably located at the surface of the ferrisilicate crystallites, From a thorough granulometric analysis involving TEM and chi(ac) data, it is concluded that, in the range from 1.5 to 4.6 wt. % Fe, the particle size distributions are significantly independent of the iron content

Plasma REST: a novel candidate biomarker of Alzheimer's disease is modified by psychological intervention in an at-risk population.

The repressor element 1-silencing transcription (REST) factor is a key regulator of the aging brain's stress response. It is reduced in conditions of stress and Alzheimer's disease (AD), which suggests that increasing REST may be neuroprotective. REST can be measured peripherally in blood plasma. Our study aimed to (1) examine plasma REST levels in relation to clinical and biological markers of neurodegeneration and (2) alter plasma REST levels through a stress-reduction intervention-mindfulness training. In study 1, REST levels were compared across the following four well-characterized groups: healthy elderly (n=65), mild cognitive impairment who remained stable (stable MCI, n=36), MCI who later converted to dementia (converter MCI, n=29) and AD (n=65) from the AddNeuroMed cohort. REST levels declined with increasing severity of risk and impairment (healthy elderly>stable MCI>converter MCI>AD, F=6.35, P<0.001). REST levels were also positively associated with magnetic resonance imaging-based hippocampal and entorhinal atrophy and other putative blood-based biomarkers of AD (Ps<0.05). In study 2, REST was measured in 81 older adults with psychiatric risk factors for AD before and after a mindfulness-based stress reduction intervention or an education-based placebo intervention. Mindfulness-based training caused an increase in REST compared with the placebo intervention (F=8.57, P=0.006), and increased REST was associated with a reduction in psychiatric symptoms associated with stress and AD risk (Ps<0.02). Our data confirm plasma REST associations with clinical severity and neurodegeneration, and originally, that REST is modifiable by a psychological intervention with clinical benefit

Are infestations of Cymomelanodactylus killing Acropora cytherea in the Chagos archipelago?

Associations between branching corals and infaunal crabs are well known, mostly due to the beneficial effects of Trapezia and Tetralia crabs in protecting host corals from crown-of-thorns starfish (e.g., Pratchett et al. 2000) and/or sedimentation (Stewart et al. 2006). These crabs are obligate associates of live corals and highly prevalent across suitable coral hosts, with 1–2 individuals per colony (Patton 1994). Cymo melanodactylus (Fig. 1) are also prevalent in branching corals, mostly Acropora, and are known to feed on live coral tissue, but are generally found in low abundance (<3 per colony) and do not significantly affect their host corals (e.g., Patton 1994). In the Chagos archipelago, however, infestations of Cymo melanodactylus were found on recently dead and dying colonies of Acropora cytherea

Effects of substrate thermal conditions on the swelling of thin intumescent coatings

The experimental study presented herein investigates the influence of the substrate thermal conditions on the behaviour of thin intumescent coatings. Steel plates coated with a commercially available solvent-based thin intumescent coating were exposed to a constant incident radiant heat flux of 50 kW/m2 in accordance with the heat-transfer rate inducing system (H-TRIS) test method. The influence of different substrate thermal conditions was investigated using sample holders capable of controlling the thermal boundary conditions at the unexposed surface of tested steel plates and comparing them to coated timber samples. Experimental results evidence that the substrate thermal conditions govern the swelling of intumescent coatings, thus their effectiveness in protecting load-bearing structural elements. The substrate temperature controls the swelling of intumescent coatings because it defines the temperature experienced by the reacting virgin coating located close to the coating-substrate interface. The physical and thermal properties of the substrate control the capacity of the system to concentrate/dissipate heat in proximity of the coating-substrate interface. In this way, the substrate thermal conditions govern the temperature evolution of the reacting intumescent coating, consequently the swelling process. Accordingly, high swelling rates were recorded for highly insulating conditions (timber substrate), while low swelling rates for poorly insulating conditions (water-cooled heat sink)

Optimising the inherent fire capacity of structures

This paper introduces a structural design optimisation methodology aimed at minimising the consequences of a fire. The methodology considers the trade-off between implementing passive fire protection measures and enhancing a structure's “inherent fire capacity”, defined as its ability to retain integrity/functionality without additional fire safety measures. The feasibility of the methodology is demonstrated through the fire safety design of a single-span, steel girder bridge. The optimisation process generates multiple Pareto-optimal solutions for minimising the maximum bridge deflection after a given fire exposure time. Passive protection ensures the bridge's functionality when facing a heavy goods vehicle fire. In the case of exposure to a car fire, solutions requiring fire protection in specific limited girder regions are identified. The decision-making process is further supported by investigating the robustness of the solutions to uncertainties in material properties and the heat flux model

Sparse 3D Point-cloud Map Upsampling and Noise Removal as a vSLAM Post-processing Step: Experimental Evaluation

The monocular vision-based simultaneous localization and mapping (vSLAM) is one of the most challenging problem in mobile robotics and computer vision. In this work we study the post-processing techniques applied to sparse 3D point-cloud maps, obtained by feature-based vSLAM algorithms. Map post-processing is split into 2 major steps: 1) noise and outlier removal and 2) upsampling. We evaluate different combinations of known algorithms for outlier removing and upsampling on datasets of real indoor and outdoor environments and identify the most promising combination. We further use it to convert a point-cloud map, obtained by the real UAV performing indoor flight to 3D voxel grid (octo-map) potentially suitable for path planning.Comment: 10 pages, 4 figures, camera-ready version of paper for "The 3rd International Conference on Interactive Collaborative Robotics (ICR 2018)

The estimation of neutrino fluxes produced by proton-proton collisions at s=14\sqrt{s}=14 TeV of the LHC

Intense and collimated neutrino beams are produced by charm and beauty particle decays from proton-proton collisions at the LHC. A neutrino experiment would be run parasitically without interrupting the LHC physics program during the collider run. We estimate the neutrino fluxes from proton-proton collisions at $\sqrt{s}=14$ TeV of the LHC with the designed luminosity, 10^{34} \lumi. By mounting about 200 tons of fiducial volume of a neutrino detector at 300 \m away from the interaction point, about 150,000 of charged current neutrino events per year can be observable.Comment: 8 pages, Accepted in JHE

Influence of heating conditions and initial thickness on the effectiveness of thin intumescent coatings

The study presented herein shows an experimental methodology aimed at analysing the effectiveness of intumescent coatings through detailed characterisation of their thermo-physical response for a range of heating conditions and applied initial dry film thickness (DFT). Steel plates coated with a commercial solvent-based thin intumescent coating were exposed to well-defined and highly-repeatable heating conditions in accordance with the H-TRIS test method. Experimental results emphasise that the swelling process and the resulting swelled thickness govern the thermo-physical response of intumescent coatings, thus their effectiveness. During swelling, the coated steel asymptotically tends to the temperature range 300–350 °C, regardless of the heating condition or DFT. Thermo-gravimetric analysis demonstrates that the coating undergoes the swelling reaction at this temperature range. Once the swelling process is completed, the steel temperature increases above 350 °C. The steel temperature acts as an indicator of the swelling process, as the reaction occurs near the steel-coating interface. The intumescent coating swells and insulates the steel substrate by displacing the already-swelled coating towards the direction of the heat source. Aiming at predicting the swelling of intumescent coatings, empirical correlations are derived: the swelling rate is governed by the heating conditions and the maximum swelled thickness is governed by the initial DFT

Assessing the feasibility, acceptability and potential effectiveness of an integrated approach to smoking cessation for new and expectant fathers: The Dads in Gear study protocol.

BACKGROUND: Evidence related to the effects of tobacco exposure in pregnancy and on infant and child health have focused on women's smoking cessation. Less often addressed is men's smoking, which when continued in fatherhood, reduces the chances of female partners' cessation and can negatively impact children's health as well as men's health. Dads in Gear (DIG) is an innovative program designed specifically for new fathers who want to reduce and quit smoking that includes three components: smoking cessation, fathering, and physical activity. The over-arching purpose of this study is to evaluate the feasibility of the DIG program and provide estimates of program efficacy. The purpose of this article is to describe the rationale and protocol for evaluating the DIG program's feasibility, acceptability and potential effectiveness. METHODS: Using a prospective, non-comparative design, the DIG program will be implemented and evaluated in six communities. The program will be offered by trained facilitators to fathers who currently smoke and want to quit. The RE-AIM framework will guide the evaluation. Open-ended questions in participant surveys, and semi-structured interviews and weekly telephone de-briefs with facilitators will provide data for a process evaluation. Estimates of effectiveness include smoking behavior, fathering and physical activity measures at baseline, end of program, and 3-month follow up. CONCLUSION: The DIG program could support positive changes with respect to smoking cessation, physical activity and overall health for men. These effects could also promote family health. The program might also provide an effective model for engaging men in other health behavior change