Consumers Preference for Hotel Amenities and Willingness to Pay in Lagos

The paper investigated user demand and pricing determinants ofhotel facilities in Lagos. The main objective was to develop a model of these perceptions that will serve as a tool or framework for prospective investors and management staff of related investments. Using information obtained from personal interviews and structured questionnaires served on users of selected hotels in Lagos Island (Ikoyi, Victoria Island and Lekki), Hedonic Model was developed with the aid of certain identified attributes. The findings revealed that security and safety attributes, location attributes, recreation and entertainment (including food and beverages), hospitality and basic attributes are some of the significant factors affecting demand and pricing of hotel in the study area. It is recommended that investors and managers should take into consideration attributes ofhotels in line with customers' value hierarchy when making investment decisions to realize optimum sustainability; and that hoteliers need to ensure that the qualities of these hotel attributes are maintained at an acceptable level by constantly reviewing customers' feedback.Keywords: Hedonic pricing; Hotels; Lagos Island; Pricing; Users demand

Asphaltene detection using Surface Enhanced Raman Scattering (SERS)

Peer reviewedPostprin

CHEMICAL COMPOSITION OF SOLID MINERALS FROM LOKOJA AND JOS IN NORTH CENTRAL NIGERIA

The structural, qualitative and quantitative analysis of grained rock samples were carried out with the view to establishing the mineral components present in the samples. Two samples were collectedfrom a mining site in Jos, Plateau State as well as from another mining site in Lokoja, Kogi State.The two samples were prepared for XRD analysis using a backloading preparation method and done with X-ray diffractometer. The analysis confirmed the presence of minerals such as Cassiterite (SnO2), Ilmenite (FeTiO3), Zircon (SiO4),Columbite (Fe), Manganoan in the ample from Jos as a result of the matching of the peaks with the database 2θ values. The percentage area integration of the various phases which correlated to the quantity of the various minerals in the sample revealed that Cassiterite(Tin Oxide) of 65.9% value was from Jos and is a Tin Ore. The grain sizes for Cassiterite (SnO2), Ilmenite (FeTiO3), Zircon (SiO4), Columbite (Fe), Manganoan are 17.674, 35.348, 37.208, 70.695, 20.199 in nm respectively. The samples from Lokoja showed the presence of Magnetite (Fe¬3O4), Quartz (SiO2), Hematite (Fe2O3) and Geothite(FeO(OH)) and confirmed the grain sizes of 28.278, 35.348, 28.278. 17.673 and 23.565 in nm respectively.The constituents of Lokoja samples, all of which contained Iron Oxide also indicate that the sample is an Iron Ore. These findings confirm the fact that the mineral resources that are present in these regions of the country areeconomically viable and have the potential to boost economy and industrial development&nbsp

Mechanism of active targeting in solid tumors with transferrin-containing gold nanoparticles

PEGylated gold nanoparticles are decorated with various amounts of human transferrin (Tf) to give a series of Tf-targeted particles with near-constant size and electrokinetic potential. The effects of Tf content on nanoparticle tumor targeting were investigated in mice bearing s.c. Neuro2A tumors. Quantitative biodistributions of the nanoparticles 24 h after i.v. tail-vein injections show that the nanoparticle accumulations in the tumors and other organs are independent of Tf. However, the nanoparticle localizations within a particular organ are influenced by the Tf content. In tumor tissue, the content of targeting ligands significantly influences the number of nanoparticles localized within the cancer cells. In liver tissue, high Tf content leads to small amounts of the nanoparticles residing in hepatocytes, whereas most nanoparticles remain in nonparenchymal cells. These results suggest that targeted nanoparticles can provide greater intracellular delivery of therapeutic agents to the cancer cells within solid tumors than their nontargeted analogs

Associations between Cognition, Gender and Monocyte Activation among HIV Infected Individuals in Nigeria.

The potential role of gender in the occurrence of HIV-related neurocognitive impairment (NCI) and associations with markers of HIV-related immune activity has not been previously examined. In this study 149 antiretroviral-naïve seropositive subjects in Nigeria (SP, 92 women and 57 men) and 58 seronegative (SN, 38 women and 20 men) were administered neuropsychological testing that assessed 7 ability domains. From the neuropsychological test scores was calculated a global deficit score (GDS), a measure of overall NCI. Percentages of circulating monocytes and plasma HIV RNA, soluble CD163 and soluble CD14 levels were also assessed. HIV SP women were found to be younger, more educated and had higher CD4+ T cell counts and borderline higher viral load measures than SP men. On the neuropsychological testing, SP women were more impaired in speed of information processing and verbal fluency and had a higher mean GDS than SN women. Compared to SP men, SP women were also more impaired in speed of information processing and verbal fluency as well as on tests of learning and memory. Numbers of circulating monocytes and plasma sCD14 and sCD163 levels were significantly higher for all SP versus all SN individuals and were also higher for SP women and for SP men versus their SN counterparts. Among SP women, soluble CD14 levels were slightly higher than for SP men, and SP women had higher viral load measurements and were more likely to have detectable virus than SP men. Higher sCD14 levels among SP women correlated with more severe global impairment, and higher viral load measurements correlated with higher monocyte numbers and sCD14 and sCD14 levels, associations that were not observed for SP men. These studies suggest that the risk of developing NCI differ for HIV infected women and men in Nigeria and, for women, may be linked to effects from higher plasma levels of HIV driving activation of circulating monocytes

Genetic and Phenotypic Association between Yield Components in Hybrid Sorghum (Sorghum bicolor (L.) Moench) populations

The magnitude of genetic expression and associations among traits are important for the prediction of response to selection in diverse environments and provide the basis for planning and evaluating breeding programs. In this regard, a cross classification mating design was used to produce hybrid sorghum populations, which were evaluated in a randomized completed block design with three replications at four environments in Northern Cameroon. Data on grain yield, days to anthesis, plant height, inflorescence length, threshing percentage and seed mass were collected and subjected to statistical genetic analyses. Significant genotype × environment interaction effects were observed for all traits. Genetic variance was essentially attributed to additive gene effects, with dominance variance for grain yield being negligible. However, the reverse was observed for threshability. Genetic variance components were much higher for plant height and grain yield than for days to anthesis, seed mass and threshability. Heritability estimates for plant height and inflorescence length were high (77 and 54 percent respectively) while the estimates for grain yield and threshability were low (14 and 5 percent respectively). Grain yield had positive genotypic correlation with most of the traits. Days to anthesis were negatively correlated with vegetative and reproductive traits. These results suggest that improvement of days to anthesis, plant height, and inflorescence length should be faster because of higher heritabilities and greater phenotypic variation. However, selection for earliness and reduced plant height would not be possible without hampering grain yield. Selecting for yield primary components namely inflorescence length and seed weight would be effective for increasing production. In addition, optimizing agronomic practices and improved experimental design would increase the selection efficiencie

VERTIGO PRESENTATION IN DEVELOPING COUNTRY, NIGERIA

ABSTRACT AIM: This study aimed at determine clinical and epidemiological features of vertigo in Ado Ekiti, south western part of Nigeria. MATERIAL AND METHOD: It is a hospital based prospective study. All patients with complaint of vertigo that presented in our department from January to December, 2012.A total of 178 out 4385 that presented to the department were recruited for this study. RESULTS: Prevalence of vertigo in this study was 4.1%. There was bimodal age distribution of 41-50 and 71-80 years. Vertigo patient presented every month of the year with peak of 20.8% in February. Most patients, 93.3% presented in our clinic with least presentation in emergency ward. Most of the referral were from general medical practitioner. High percentage, 70.8% recurrent cases was recorded. Vertigo attack duration of minutes or more were commoner and responsible for 60.1% of the studied cases. Associated symptoms were 21.3% nausea, 5.1% vomiting, and 12.8% fall

Pharmacokinetics and tumor dynamics of the nanoparticle IT-101 from PET imaging and tumor histological measurements

IT-101, a cyclodextrin polymer-based nanoparticle containing camptothecin, is in clinical development for the treatment of cancer. Multiorgan pharmacokinetics and accumulation in tumor tissue of IT-101 is investigated by using PET. IT-101 is modified through the attachment of a 1,4,7,10-tetraazacyclododecane-1,4,7-Tris-acetic acid ligand to bind ^(64)Cu^(2+). This modification does not affect the particle size and minimally affects the surface charge of the resulting nanoparticles. PET data from ^(64)Cu-labeled IT-101 are used to quantify the in vivo biodistribution in mice bearing Neuro2A s.c. tumors. The ^(64)Cu-labeled IT-101 displays a biphasic plasma elimination. Approximately 8% of the injected dose is rapidly cleared as a low-molecular-weight fraction through the kidneys. The remaining material circulates in plasma with a terminal half-life of 13.3 h. Steadily increasing concentrations, up to 11% injected dose per cm^3, are observed in the tumor over 24 h, higher than any other tissue at that time. A 3-compartment model is used to determine vascular permeability and nanoparticle retention in tumors, and is able to accurately represent the experimental data. The calculated tumor vascular permeability indicates that the majority of nanoparticles stay intact in circulation and do not disassemble into individual polymer strands. A key assumption to modeling the tumor dynamics is that there is a “sink” for the nanoparticles within the tumor. Histological measurements using confocal microscopy show that IT-101 localizes within tumor cells and provides the sink in the tumor for the nanoparticles

Investigation and Comparison of Heat Generated by Coloured Metallic Plates in Response to the Emissive and Absobtion Power of the Surfaces of the Coloured Plate

A colour test was carried out to determine the rates of absorption and emission of infrared radiation by coloured hollowed metallic plates which result in increase in temprature of the holllowed plates at maximum radiation of 750 Wm-2 at Abeokuta 7.198305 and Longitude 3.439533 during the month of March 2013. Five hollow metallic plates of different paint colours (black, green, red, blue and white) were exposed to sunlight simultaneously and the temperature generated in each plate was recorded using a data logger. A wooden box that was divided into five cavities was constructed and lagged with wood shavings to provide insulation and the five coloured hollowed metallic plates of dimension d=4h were inserted in it. The choice dimension d=4h is to minimise shading of the inside of the plate (d is the diameter of each of the plates and h is the height) the top of the plates were covered with a 5 mm thick glass. The top cover plates were securely laid tightly to both the wooden box and the tip of the plates to prevent heat loss to the surrounding and also from crossing from one plate to another.  This arraignment is similar to that of a flat plate collector and calorimeter experiment. The centre of each of the plate was connected to five probes of a data logger and the temperature of changes inside the plates are logged and recorded