Anomalous spin-dependent behaviour of one-dimensional subbands

We report a new electron interaction effect in GaAs/AlGaAs quantum wires. Using DC-bias spectroscopy, we show that large and abrupt changes occur to the energies of spin-down (lower energy) states as they populate. The effect is not observed for spin-up energy states. At B=0, interactions have a pronounced effect, in the form of the well-known 0.7 Structure. However, our new results show that interactions strongly affect the energy spectrum at all magnetic fields, from 0 to 16T, not just in the vicinity of the 0.7 Structure.Comment: 4 pages, 2 figure

A simple stochastic model for the evolution of protein lengths

We analyse a simple discrete-time stochastic process for the theoretical modeling of the evolution of protein lengths. At every step of the process a new protein is produced as a modification of one of the proteins already existing and its length is assumed to be random variable which depends only on the length of the originating protein. Thus a Random Recursive Trees (RRT) is produced over the natural integers. If (quasi) scale invariance is assumed, the length distribution in a single history tends to a lognormal form with a specific signature of the deviations from exact gaussianity. Comparison with the very large SIMAP protein database shows good agreement.Comment: 12 pages, 4 figure

Minimax studies

Effect of nonzero initial conditions on selection of minimax controllers for large launch vehicles and extremal bounded amplitude bounded rate inputs to linear system

Guidelines for the management of the foot health problems associated with rheumatoid arthritis

Background. Rheumatoid arthritis (RA) as a chronic systemic disease, commonly affects the feet, impacting negatively on patients' quality of life. Specialist podiatrists have a prime role to play in the assessment and management of foot and ankle problems within this patient group. However, it has been identified that in many areas there is no specialist podiatry service, with many patients being managed by non‐specialist podiatrists. Therefore, the North West Clinical Effectiveness Group for the Foot in Rheumatic Diseases (NWCEG) identified the need to develop ‘practitioner facing’ guidelines for the management of specific foot health problems associated with RA. Methods. Members of a guideline development group from the NWCEG each reviewed the evidence for specific aspects of the assessment and management of foot problems. Where evidence was lacking, ‘expert opinion’ was obtained from the members of the NWCEG and added as a consensus on current and best practice. An iterative approach was employed, with the results being reviewed and revised by all members of the group and external reviewers before the final guideline document was produced. Results. The management of specific foot problems (callus, nail pathology, ulceration) and the use of specific interventions (foot orthoses, footwear, patient education, steroid injection therapy) are detailed and standards in relation to each are provided. A diagrammatic screening pathway is presented, with the aim of guiding nonspecialist podiatrists through the complexity of assessing and managing those patients with problems requiring input from a specialist podiatrist and other members of the rheumatology multidisciplinary team. Conclusion. This pragmatic approach ensured that the guidelines were relevant and applicable to current practice as ‘best practice’, based on the available evidence from the literature and consensus expert opinion. These guidelines provide both specialist and non‐specialist podiatrists with the essential and ‘gold standard’ aspects of managing people with RA‐related foot problems

Energy-level pinning and the 0.7 spin state in one dimension: GaAs quantum wires studied using finite-bias spectroscopy

We study the effects of electron-electron interactions on the energy levels of GaAs quantum wires (QWs) using finite-bias spectroscopy. We probe the energy spectrum at zero magnetic field, and at crossings of opposite-spin-levels in high in-plane magnetic field B. Our results constitute direct evidence that spin-up (higher energy) levels pin to the chemical potential as they populate. We also show that spin-up and spin-down levels abruptly rearrange at the crossing in a manner resembling the magnetic phase transitions predicted to occur at crossings of Landau levels. This rearranging and pinning of subbands provides a phenomenological explanation for the 0.7 structure, a one-dimensional (1D) nanomagnetic state, and its high-B variants.Comment: 6 pages, 4 figure

Turning up the lights - fabrication of brighter SERRS nanotags

Brighter SERRS nanotags ideal for improved SERRS imaging were prepared by the controlled addition of electrolyte producing a dimer enriched solution, which was incubated with a Raman reporter before being stabilised by a polyethylene glycol (PEG) shell