Prinsip Pendekatan Morfologi dalam Pengkajian Nomina Deverbal dan Implementasi Pengajarannya

In the study of words derivation, morphological approaches are used integratedly, not separately. The arrangement model is foc used on the morphophonemics of derivative words the proces model is applied in forming and analyzing derivative words, and paradigm model is used to know the form and meaning systems of various kinds of derivative words. Key words: morphological approach, arrangement model, process model, paradigm model

Perancangan Mebel Fleksibel Pada May May Salon Tunjungan Plaza Surabaya

Tunjungan Plaza is one of the largest and most famous malls in Surabaya and even in Southeast Asia, this mall is demanded by the people of Surabaya due to the completeness of products and services offered, The salon is one of the examples of services at Tunjungan Plaza Mall that is highly demanded by the public due to it\u27s popularity and quality. For example, May May Salon that I used as the site of my design project, the most popular activity in this salon is haircut and nail art, but the amount of facilities for both activities are not the same, so that it can\u27t improve the services of this salon, therefore it needs a flexible furniture that can comply needs in one furniture, it can also be used as a new innovation

Cytochrome P450 CYP1B1 interacts with 8-<i>methoxypsoralen</i> (8-MOP) and influences psoralen-Ultraviolet A (PUVA) sensitivity

Background: There are unpredictable inter-individual differences in sensitivity to psoralen-UVA (PUVA) photochemotherapy, used to treat skin diseases including psoriasis. Psoralens are metabolised by cytochrome P450 enzymes (P450), and we hypothesised that variability in cutaneous P450 expression may influence PUVA sensitivity. We previously showed that P450 CYP1B1 was abundantly expressed in human skin and regulated by PUVA, and described marked inter-individual differences in cutaneous CYP1B1 expression.Objectives: We investigated whether CYP1B1 made a significant contribution to 8-methoxypsoralen (8-MOP) metabolism, and whether individuality in CYP1B1 activity influenced PUVA sensitivity.Methods: We used E. coli membranes co-expressing various P450s and cytochrome P450 reductase (CPR) to study 8-MOP metabolism and cytotoxicity assays in CYP1B1-expressing mammalian cells to assess PUVA sensitivity.Results: We showed that P450s CYP1A1, CYP1A2, CYP1B1, CYP2A6 and CYP2E1 influence 8-MOP metabolism. As CYP1B1 is the most abundant P450 in human skin, we further demonstrated that: (i) CYP1B1 interacts with 8-MOP (ii) metabolism of the CYP1B1 substrates 7-ethoxyresorufin and 17-b-estradiol showed concentration-dependent inhibition by 8-MOP and (iii) inhibition of 7-ethoxyresorufin metabolism by 8-MOP was influenced by CYP1B1 genotype. The influence of CYP1B1 on PUVA cytotoxicity was further investigated in a Chinese hamster ovary cell line, stably expressing CYP1B1 and CPR, which was more sensitive to PUVA than control cells, suggesting that CYP1B1 metabolises 8-MOP to a more phototoxicmetabolite(s).Conclusion: Our data therefore suggest that CYP1B1 significantly contributes to cutaneous 8-MOP metabolism, and that individuality in CYP1B1 expression may influence PUVA sensitivity

The Potentials of Groundnut Shell Ash as Concrete Admixture

Rosana G. Moreira, Editor-in-Chief; Texas A&M UniversityThis is a paper from International Commission of Agricultural Engineering (CIGR, Commission Internationale du Genie Rural) E-Journal Volume 8 (2006): The Potentials of Groundnut Shell Ash as Concrete Admixture. Manuscript BC 05 012. Vol. VIII. February, 200