Humans Sensitivity Distribution in Perceptual Space by a Wearable Haptic Sleeve

It is very important to understand humans’ perception when the other communication modalities like vision and audition are partially or fully impaired. Therefore, this paper tries to give a brief overview on humans’ sensitivity distribution in perceptual space. During our experiments, a wearable haptic sleeve consisted of 7 vibro-actuators was used to stimulate subjects arm to convey haptic feedback. The basic research questions in this study are: 1) whether humans’ perception linearly correlated with the actuation frequency, haptic feedback in our scenario 2) humans’ ability to generalise templates via the wearable haptic sleeve. Those findings would be useful to increase humans’ perception when humans have to work with fully or partially impaired perception in their day-to-day life

Nuclear Magnetic Resonance and Hyperfine Structure

Contains reports on five research projects

Nuclear Magnetic Resonance and Hyperfine Structure

Contains research objectives and reports on six research objectives

Neurophysiology

Contains research objectives and reports on nine research projects.The Teagle Foundation, Inc.U.S. Air Force (Aeronautical Systems Division) under Contract AF33(616)-7783Bell Telephone Laboratories, Inc.National Institutes of Health [Grant M-4235-(C1)]National Institutes of Health (Grant B-1865-(C3))National Institutes of Health (Grant MP-4737)National Institutes of Health (Grant B-2480(C1)

Agronomic and Kernel Compositional Traits of Blue Maize Landraces from the Southwestern United States

Diverse landraces of maize have been cultivated for centuries in the southwestern United States and northern Mexico primarily for human food consumption. A striking feature of these landraces is the wide array of kernel colors displayed. Traditional cultivation is declining, but blue maize has received increasing commercial interest due to rising consumer demand for unique food products with health benefits and special culinary uses. We evaluated grain yield, agronomic and morphological traits, and analyzed the kernel biochemical composition of five blue and one purple landraces representative of diversity in the Southwest. These were compared with selected open-pollinated populations derived from Southwest and Corn Belt blue maize at several New Mexico locations in 2012 and 2013. Kernel amino acids, oil, protein, starch, fatty acids, crude fiber, ash and anthocyanin pigment contents were determined. Grain yield across all locations, years, and accessions averaged 2.11 Mg ha−1. Navajo Blue and Hopi Blue were the highest and lowest yielding accessions, respectively. The majority of southwestern landraces displayed higher oil content, and two displayed higher protein content, than the Corn Belt Dent variety. Little variation in total amino acid content was observed. Several southwestern floury accessions displayed ∼10% greater lysine and methionine than did dent or flint genotypes. Considerable variation for plant, ear, and kernel compositional traits within and across southwestern landraces was consistent with the presence of racial admixtures. The health-promoting properties of anthocyanin-rich landraces contribute to sound dietary nutrition and human health. This study further illustrates the diversity of southwestern maize and supports the rationale for their continued conservation through sustained cultivation and utilization. Directed selection to improve grain yield and uniformity will be necessary to enhance their potential for commercial production

Extracellular, cell-permeable survivin inhibits apoptosis while promoting proliferative and metastatic potential

The tumour microenvironment is believed to be involved in development, growth, metastasis, and therapy resistance of many cancers. Here we show survivin, a member of the inhibitor of apoptosis protein (IAP) family, implicated in apoptosis inhibition and the regulation of mitosis in cancer cells, exists in a novel extracellular pool in tumour cells. Furthermore, we have constructed stable cell lines that provide the extracellular pool with either wild-type survivin (Surv-WT) or the previously described dominant-negative mutant survivin (Surv-T34A), which has proven pro-apoptotic effects in cancer cells but not in normal proliferating cells. Cancer cells grown in conditioned medium (CM) taken from Surv-WT cells absorbed survivin and experienced enhanced protection against genotoxic stresses. These cells also exhibited an increased replicative and metastatic potential, suggesting that survivin in the tumour microenvironment may be directly associated with malignant progression, further supporting survivin's function in tumourigenesis. Alternatively, cancer cells grown in CM taken from the Surv-T34A cells began to apoptose through a caspase-2- and caspase-9-dependent pathway that was further enhanced by the addition of other chemo- and radiotherapeutic modalities. Together our findings suggest a novel microenvironmental function for survivin in the control of cancer aggressiveness and spread, and should result in the genesis of additional cancer treatment modalities

Neurophysiology

Contains research objectives.Bell Telephone Laboratories, Inc.The Teagle Foundation, Inc.National Institutes of Health (Grant NB-01865-05)National Institutes of Health (Grant MH-04737-02)U.S. Air Force (Aeronautical Systems Division) under Contract AF33(616)-778

Who Benefits From Teams? Comparing Workers, Supervisors, and Managers

This paper offers a political explanation for the diffusion and sustainability of team-based work systems by examining the differential outcomes of team structures for 1200 workers, supervisors, and middle managers in a large unionized telecommunications company. Regression analyses show that participation in self-managed teams is associated with significantly higher levels of perceived discretion, employment security, and satisfaction for workers and the opposite for supervisors. Middle managers who initiate team innovations report higher employment security, but otherwise are not significantly different from their counterparts who are not involved in innovations. By contrast, there are no significant outcomes for employees associated with their participation in offline problem-solving teams

Biofeedback for training balance and mobility tasks in older populations: a systematic review

<p>Abstract</p> <p>Context</p> <p>An effective application of biofeedback for interventions in older adults with balance and mobility disorders may be compromised due to co-morbidity.</p> <p>Objective</p> <p>To evaluate the feasibility and the effectiveness of biofeedback-based training of balance and/or mobility in older adults.</p> <p>Data Sources</p> <p>PubMed (1950-2009), EMBASE (1988-2009), Web of Science (1945-2009), the Cochrane Controlled Trials Register (1960-2009), CINAHL (1982-2009) and PsycINFO (1840-2009). The search strategy was composed of terms referring to biofeedback, balance or mobility, and older adults. Additional studies were identified by scanning reference lists.</p> <p>Study Selection</p> <p>For evaluating effectiveness, 2 reviewers independently screened papers and included controlled studies in older adults (i.e. mean age equal to or greater than 60 years) if they applied biofeedback during repeated practice sessions, and if they used at least one objective outcome measure of a balance or mobility task.</p> <p>Data Extraction</p> <p>Rating of study quality, with use of the Physiotherapy Evidence Database rating scale (PEDro scale), was performed independently by the 2 reviewers. Indications for (non)effectiveness were identified if 2 or more similar studies reported a (non)significant effect for the same type of outcome. Effect sizes were calculated.</p> <p>Results and Conclusions</p> <p>Although most available studies did not systematically evaluate feasibility aspects, reports of high participation rates, low drop-out rates, absence of adverse events and positive training experiences suggest that biofeedback methods can be applied in older adults. Effectiveness was evaluated based on 21 studies, mostly of moderate quality. An indication for effectiveness of visual feedback-based training of balance in (frail) older adults was identified for postural sway, weight-shifting and reaction time in standing, and for the Berg Balance Scale. Indications for added effectiveness of applying biofeedback during training of balance, gait, or sit-to-stand transfers in older patients post-stroke were identified for training-specific aspects. The same applies for auditory feedback-based training of gait in older patients with lower-limb surgery.</p> <p>Implications</p> <p>Further appropriate studies are needed in different populations of older adults to be able to make definitive statements regarding the (long-term) added effectiveness, particularly on measures of functioning.</p

Internet of Things for Environmental Sustainability and Climate Change

Our world is vulnerable to climate change risks such as glacier retreat, rising temperatures, more variable and intense weather events (e.g., floods, droughts, and frosts), deteriorating mountain ecosystems, soil degradation, and increasing water scarcity. However, there are big gaps in our understanding of changes in regional climate and how these changes will impact human and natural systems, making it difficult to anticipate, plan, and adapt to the coming changes. The IoT paradigm in this area can enhance our understanding of regional climate by using technology solutions, while providing the dynamic climate elements based on integrated environmental sensing and communications that is necessary to support climate change impacts assessments in each of the related areas (e.g., environmental quality and monitoring, sustainable energy, agricultural systems, cultural preservation, and sustainable mining). In the IoT in Environmental Sustainability and Climate Change chapter, a framework for informed creation, interpretation and use of climate change projections and for continued innovations in climate and environmental science driven by key societal and economic stakeholders is presented. In addition, the IoT cyberinfrastructure to support the development of continued innovations in climate and environmental science is discussed