519 research outputs found

    Penetrating Ionizing Radiation Levels Observed in the Lower Arkansas and White River Valleys of Arkansas

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    Environmental levels of penetrating ionizing radiation were measured in the lower Arkansas and White River valleys of Arkansas. Measurements of environmental gamma and cosmic rays were made using a portable high pressure ionization chamber. The surveyed area encompassed a large coal-fired industrial plant. Observed exposure rates ranged from 5.9 microRoentgens per hour (μR/h) to 13.4 μR/h. The average exposure rate for the region was 8.8 μR/h. This value corresponds to 77 millirem (mrem) or 0.77 milliSieverts (mSv) per year. In comparison, a prior state-wide survey reported an average dose equivalent rate of 78.2 mrem (0.782 mSv) per year in Arkansas

    Boundary conditions on the early Sun from ancient cosmogenic neon in meteorites

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    Isotopic analysis of neon from individual grains of the meteorites Murchison (CM) and Kapoeta (howardite) shows large enrichments of cosmogenic neon in grains with solar flare tracks. The quantity of this component is incompatible with galactic cosmic ray or solar cosmic ray irradiation under present conditions and is attributed to irradiation by energetic flares from an early active Sun. Handpicked grains from each meteorite were grouped according to the presence or absence of solar flare heavy ion tracks, and these four samples were analyzed with an ion counting noble gas mass spectrometer

    Evidence in meteorites for an active early Sun

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    The amounts of neon-21 found in meteorite particles indicate that the Sun experienced a period of intense solar flare activity approximately 4.5 billion years ago

    Precompaction irradiation effects: Particles from an early active sun?

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    Two recent studies have shown that solar flare irradiated grains from Murchison and Kapoeta have excess spallogenic Ne-21 compared to unirradiated grains, indicating large precompaction particle irradiation effects. The quantity of cosmogenic neon in these grains presents serious difficulties for either galactic cosmic ray or normal solar flare sources. In the first study it was suggested that the effect might be the result of exposure to an early active sun. The more recent experiment both confirms the earlier results and provides constraints on the characteristic energy spectrum on the irradiation. The first results were obtained from Murchison olivines and Kapoeta pyroxenes by mass spectrometric analysis of sets of grains selected on the basis of the presence or absence of solar flare particle tracks. In the second work plagioclase feldspar grains from Kapoeta were studied

    Epidermal growth factor (EGF)-like repeats of human tenascin-C as ligands for EGF receptor.

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    Signaling through growth factor receptors controls such diverse cell functions as proliferation, migration, and differentiation. A critical question has been how the activation of these receptors is regulated. Most, if not all, of the known ligands for these receptors are soluble factors. However, as matrix components are highly tissue-specific and change during development and pathology, it has been suggested that select growth factor receptors might be stimulated by binding to matrix components. Herein, we describe a new class of ligand for the epidermal growth factor (EGF) receptor (EGFR) found within the EGF-like repeats of tenascin-C, an antiadhesive matrix component present during organogenesis, development, and wound repair. Select EGF-like repeats of tenascin-C elicited mitogenesis and EGFR autophosphorylation in an EGFR-dependent manner. Micromolar concentrations of EGF-like repeats induced EGFR autophosphorylation and activated extracellular signal-regulated, mitogen-activated protein kinase to levels comparable to those induced by subsaturating levels of known EGFR ligands. EGFR-dependent adhesion was noted when the ligands were tethered to inert beads, simulating the physiologically relevant presentation of tenascin-C as hexabrachion, and suggesting an increase in avidity similar to that seen for integrin ligands upon surface binding. Specific binding to EGFR was further established by immunofluorescence detection of EGF-like repeats bound to cells and cross-linking of EGFR with the repeats. Both of these interactions were abolished upon competition by EGF and enhanced by dimerization of the EGF-like repeat. Such low affinity behavior would be expected for a matrix-tethered ligand; i.e., a ligand which acts from the matrix, presented continuously to cell surface EGF receptors, because it can neither diffuse away nor be internalized and degraded. These data identify a new class of insoluble growth factor ligands and a novel mode of activation for growth factor receptors

    Teaching Undergraduate Accounting Majors How To Interpret The Accounting Standards Codification: An Alternative To Research Cases

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    Professional accountants regularly search the FASB’S Accounting Standards Codification to find answers to financial accounting questions. Accounting educators know this and frequently use research cases in an attempt to help students begin developing this ability, but many students struggle with these cases because they have not been taught how to interpret the Codification and apply its provisions. As a result, research cases often fail to accomplish one of the main purposes for which they are assigned. The authors believe that teaching undergraduate accounting majors how to interpret the Codification is best achieved through an in-class explanation of the process by which the Codification is converted into formulas and journal entries – an approach that they have named the “classroom approach” and that is described in this paper
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