Application fever: Reviewing the causes, costs, and cures for residency application inflation

Over the past decade, the number of residency applications submitted per applicant has nearly doubled. This epidemic of Application Fever is expensive for applicants, burdensome for programs, and ultimately does not improve overall Match outcomes. In this review, we discuss the phenomenon of Application Fever, with a focus on contributing factors and costs of this behavior. Application Fever has its origins in the early 1990s. At that time, the number of residency applicants began to outpace the number of available positions. Because an applicant who applies to more residency programs has a greater probability of securing a residency position than an otherwise equivalent applicant who applies to fewer, overapplication became a dominant strategy and residency applicants began to apply to more residency programs each year. This trend was enhanced and enabled by the introduction of the Electronic Residency Application Service (ERAS). Although Application Fever is a rational decision for applicants, it imposes a substantial evaluative burden on program directors and necessitates the use of convenience screening metrics. We then briefly review potential solutions, including informational strategies, application limits, and marketplace incentives to reduce application numbers. Although a fixed cap on applications would reduce application numbers and facilitate a holistic selection process, greater transparency from residency programs regarding their selection criteria would be required to help applicants choose where to apply. To improve the residency application process for programs and applicants alike, we call upon the medical community to further study Application Fever and carefully consider solutions, including fixed application caps

Compressibility and Permeability of Solidified Dredged Marine Soils (DMS) with the Addition of Cement and/or Waste Granular Materials (WGM)

Dredged marine soils that obtained from dredging work were characterize as geo-waste, which is prone to be dumped rather than to be reused. This type of soil is high in compressibility and low in load bearing capacity. The engineering properties of this soft soil can be improve via soil solidification method. Cement is the common hydraulic binder used in soil solidification, were found to generate the emission of greenhouse gasses (GHG), particularly carbon dioxide (CO2) which also had affected the earth’s atmosphere. Therefore, there has been an increasing interest in using alternate pozzolanic materials such as waste granular materials (WGM) to fully or partially substituted the use of cement in soil solidification. WGM such as coal bottom ash (BA) and palm oil clinker (POC) were opted due to its pozzolanic properties. Prior to the planning of reclamation work using DMS admixed with conventional and/or alternate pozzolanic materials, the consolidation characteristics of the admixed materials must be acknowledged. Hence, the present study will examine the amount of settlement and coefficient of permeability (k) of DMS treated with cement and/or WGM in laboratory-scale experiments. Samples were prepared in various proportion in order to examine the individual effect of the cement and/or alternate pozzolanic materials on compressibility and permeability. For cement-admixed DMS, sample with 20 % of cement have significantly reduced the settlement than untreated and 10 % cemented DMS. For WGM-admixed DMS, the initial void ratio is low as compared to the untreated DMS due to the rearrangement of soil particles, which is densely packed. For cement-WGM-admixed DMS, samples of 15C50BA and 15C50POC displayed significant settlement reduction than 10C100BA, 10C100POC and untreated samples

Pengoptimalan Persediaan dengan Metode Simpleks pada PT Xyz

Penerapan model pemrograman linier sangat membantu manajer operasidalam pengambilan keputusan untuk menentukan produk mana yang menjadi prior-itas utama untuk disediakan. Tahap awal dalam pengembangan model Program Lin-ier adalah mengidentifikasi semua variabel, selanjutnya menetapkan fungsi tujuan(Z) dan fungsi kendala. Dalam hal menentukan persediaan yang optimal digunakanMetode Simpleks dalam Program Linier. Dengan melakukan pengkajian pada PTXYZ maka ditentukan bahwa fungsi tujuan yang ingin dicapai adalah memaksi-mumkan laba Perusahaan dan fungsi kendala adalah kapasitas penyimpanan danjumlah permintaan. Pengolahan data dilakukan dengan menggunakan softwarePOM-QM. Berdasarkan hasil perhitungan disimpulkan bahwa kombinasi persedi-aan yang dilakukan Perusahaan mencapai tingkat optimal untuk produk pupuk urea2.000 packs, kieserite 8.000 packs dan rock phosphate 10.000 packs

Task-Specific Sensor Planning for Robotic Assembly Tasks

When performing multi-robot tasks, sensory feedback is crucial in reducing uncertainty for correct execution. Yet the utilization of sensors should be planned as an integral part of the task planning, taken into account several factors such as the tolerance of different inferred properties of the scene and interaction with different agents. In this paper we handle this complex problem in a principled, yet efficient way. We use surrogate predictors based on open-loop simulation to estimate and bound the probability of success for specific tasks. We reason about such task-specific uncertainty approximants and their effectiveness. We show how they can be incorporated into a multi-robot planner, and demonstrate results with a team of robots performing assembly tasks

The distribution of lead between sea salt dust, and lead-rich aerosols in the mid South Pacific easterlies at American Samoa

Aerosols in the South Pacific Easterlies have been sampled at American Samoa with a cascade impactor and analysed for Pb, Ba, K, Ca, Sr, and Rb by isotope dilution mass spectrometry using ultraclean procedures. Some 84% of the Pb was found in fine (≤ 0.5 μm) aerosols which were collected on the backup filter with an efficiency of only 33%. Sea salt and eroded terrestrial material (dust) containing 6% and <1% respectively, of the Pb (sea salt indexed by the metals K, Ca, Sr, and Rb and dust indexed by Ba) were collected on early stages of the impactor, although 65% of the dust, because of its larger size, was lost to surfaces of the rain shelter before reaching the impactor. The remaining 10% of the Pb was associated with plant leaf waxes of continental origin which produced Pb and Ba peaks on stage 4 (0.5 μ) of the impactor

Anthropogenic lead isotopes in Antarctica

We report the first measurements of Pb isotopes in Antarctic snow, which show that even recent snow containing 2.3 pg/g is highly polluted with anthropogenic Pb. This follows from a comparison of isotope abundances of Pb in surface snow and terrestrial dust extracted from ancient Antarctic ice (Dome C, depth 308 m, approximate age 7,500 a BP), the latter being distinctly more radiogenic. This result is independent of geochemical arguments based on measurements of Al, Na and SO_4. South America is suggested as a likely source of this anthropogenic Pb. The presence of significantly less radiogenic Pb in the snow adjacent to two Antarctic base stations indicates that there is contamination from station emissions, although emission from Australia is an alternative explanation for a site 33 km from Dumont d'Urville

Influence of sub-inhibitory concentrations of antimicrobials on micrococcal nuclease and biofilm formation in Staphylococcus aureus

Abstract A major contributor to biomaterial associated infection (BAI) is Staphylococcus aureus. This pathogen produces a protective biofilm, making eradication difficult. Biofilms are composed of bacteria encapsulated in a matrix of extracellular polymeric substances (EPS) comprising polysaccharides, proteins and extracellular DNA (eDNA). S. aureus also produces micrococcal nuclease (MN), an endonuclease which contributes to biofilm composition and dispersion, mainly expressed by nuc1. MN expression can be modulated by sub-minimum inhibitory concentrations of antimicrobials. We investigated the relation between the biofilm and MN expression and the impact of the application of antimicrobial pressure on this relation. Planktonic and biofilm cultures of three S. aureus strains, including a nuc1 deficient strain, were cultured under antimicrobial pressure. Results do not confirm earlier findings that MN directly influences total biomass of the biofilm but indicated that nuc1 deletion stimulates the polysaccharide production per CFU in the biofilm in in vitro biofilms. Though antimicrobial pressure of certain antibiotics resulted in significantly increased quantities of polysaccharides per CFU, this did not coincide with significantly reduced MN activity. Erythromycin and resveratrol significantly reduced MN production per CFU but did not affect total biomass or biomass/CFU. Reduction of MN production may assist in the eradication of biofilms by the host immune system in clinical situations