Unequal Lives: The State of Black Women and Families in the Rural South

This report aims to shed light on the most significant and persistent barriers to success, opportunity, and economic security for lower-income women and families in the rural South. It also provides an in-depth analysis of the economic security, health, and overall wellbeing of women living in nine counties across the rural South in the states of Alabama, Georgia and Mississippi.Using the most recent data available from the U.S. Census Bureau American Community Survey, various city and regional agencies, and other relevant sources, the report focuses on six main issue areas that shape the lives of women and families, including poverty, income and employment; education and health; and public infrastructure and housing. The report focuses on nine counties in three states that are persistently poor as defined by the United States Department of Agriculture (USDA). These are counties where 20 percent or more of the population have lived in poverty for five consecutive census years

Informational Warfare

Recent empirical and theoretical work suggests that reputation was an important mediator of access to resources in ancestral human environments. Reputations were built and maintained by the collection, analysis, and dissemination of information about the actions and capabilities of group members-that is, by gossiping. Strategic gossiping would have been an excellent strategy for manipulating reputations and thereby competing effectively for resources and for cooperative relationships with group members who could best provide such resources. Coalitions (cliques) may have increased members' abilities to manipulate reputations by gossiping. Because, over evolutionary time, women may have experienced more within-group competition than men, and because female reputations may have been more vulnerable than male reputations to gossip, gossiping may have been a more important strategy for women than men. Consequently, women may have evolved specializations for gossiping alone and in coalitions. We develop and partially test this theory

BRCA1 Zinc RING Finger Domain Disruption Alters Caspase Response in Ovarian Surface Epithelial Cells

BACKGROUND: The frequently occurring 185delAG mutation occurs in the amino-terminal zinc RING domain of the breast and ovarian cancer susceptibility gene, BRCA1. We sought to determine differential cell viability and apoptotic response of human ovarian surface epithelial cells with and without the 185delAG mutation. RESULTS: BRCA1wt and BRCA1+ cells were treated with staurosporine. Cell proliferation assays showed BRCA1wt cells grew to a greater extent compared to BRCA1+ cells. Trypan blue exclusion assays confirmed this observation. Western immunoblot analysis revealed that caspase 3 levels were higher after staurosporine treatment in BRCA1+ cells than in wild type cells, while full length DNA Fragmentation Factor 45 levels were lower in BRCA1+ cells. While there was no significant difference in levels of excision repair cross complementing protein1 (ERCC1) with BRCA1 status, BRCA1+ cells demonstrated cleavage of polyribose ADP polymerase (PARP) before wild type cells. CONCLUSIONS: Disruption of the BRCA1 RING domain caused altered cell viability and caspase-dependent apoptotic response after chemotoxic stress

Teaching and learning history in Australian primary schools: pedagogical shifts, complexities and opportunities

From 2011 the teaching and learning of History will be expanded into all primary schools (Kindergarten – Year 6) throughout Australia under a National Curriculum, including the formal preschool/kindergarten year. History as one of four core subjects will replace current studies of society and environment curriculum taught in primary schools across. The curriculum implementation process will involve a cultural and pedagogical shift as primary teachers make adjustments to the discipline of History. This article begins with an outline of the current curriculum context. An analysis of the New South Wales Human Society and Its Environment and the Australian Curriculum: History Draft Consultation documents follows. The findings indicate that the History Draft Consultation lacks clear guidance for teachers and has a number of shortcomings compared to the NSW HSIE syllabus. There are opportunities, however, for primary teachers because of the broad similarities of content knowledge in both documents and the embedded historical concepts in the NSW syllabus document