635 research outputs found

    Exploring the potential of heat as a service in decarbonization: Evidence needs and research gaps

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    The need to accelerate the decarbonization of heating, as well as the rise of the ‘smart home’, mean that there is an increasing focus on the role of innovative consumer offerings in driving the shift to zero carbon domestic heating. In this context, Heat as a Service (HaaS) business models, which provide consumers with an agreed heating plan rather than simply paying for units of fuel, are receiving increased attention. This paper explores HaaS based on insights from facilitated group discussions with key stakeholders, and learning from HaaS trials, in the United Kingdom. Results identified evidence needs and research gaps related to: addressing issues of trust between consumers and suppliers, supportive policies, financing business models, and openness and interoperability of technology and data. Based on the findings, we propose policy and research recommendations to better understand the role of HaaS business models in decarbonization

    Suicide first aid guidelines for assisting persons from immigrant or refugee background: a Delphi study

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    Objective: Suicide rates vary across different cultural groups and some immigrant or refugee populations display higher risk for suicide. This study aimed to produce guidelines to help members of the public provide assistance to a person from an immigrant or refugee background who is having suicidal thoughts or displaying suicidal behaviour. Method: The Delphi expert consensus method was used to identify warning signs and first aid actions to include in guidelines. Forty- four professionals and/or advocates with lived experience were asked to rate whether each statement contained in an online questionnaire should be included in the guidelines and to suggest additional statements considered by the respondent to be particularly relevant to a person from an immigrant or refugee background. The Delphi process started with 473 statements and 80 new items were written based on suggestions from panel members. Results: Out of the total 553 statements, 345 were endorsed as appropriate warning signs or helping actions. These statements were used to develop the guidelines. Discussion: The guidelines specific to people from immigrant or refugee backgrounds contain additional items to those included in similar guidelines for English-speaking countries. The guidelines may be used for gatekeeper training for suicide prevention in culturally diverse societies

    In or out? Barriers and facilitators to refugee-background young people accessing mental health services

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    Refugee young people have been identified as a group with high risk for mental health problems, due to their experience of trauma, forced migration, and stressors associated with settlement. A high prevalence of mental health problems is reported in this group, however some research suggests refugee young people have low rates of mental health service access. There is little information available on barriers and facilitators to mental service delivery for this group. Using data from 15 focus groups and five key informant interviews with a total of 115 service providers from 12 agencies in Melbourne, Australia, this paper explores barriers and facilitators to engaging young people from refugee backgrounds with mental health services. Eight key themes emerged: cultural concepts of mental health, illness, and treatment; service accessibility; trust; working with interpreters; engaging family and community; the style and approach of mental health providers; advocacy; and continuity of care

    Biodesalination: an emerging technology for targeted removal of Na+and Cl−from seawater by cyanobacteria

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    Although desalination by membrane processes is a possible solution to the problem of freshwater supply, related cost and energy demands prohibit its use on a global scale. Hence, there is an emerging necessity for alternative, energy and cost-efficient methods for water desalination. Cyanobacteria are oxygen-producing, photosynthetic bacteria that actively grow in vast blooms both in fresh and seawater bodies. Moreover, cyanobacteria can grow with minimal nutrient requirements and under natural sunlight. Taking these observations together, a consortium of five British Universities was formed to test the principle of using cyanobacteria as ion exchangers, for the specific removal of Na+ and Cl− from seawater. This project consisted of the isolation and characterisation of candidate strains, with central focus on their potential to be osmotically and ionically adaptable. The selection panel resulted in the identification of two Euryhaline strains, one of freshwater (Synechocystis sp. Strain PCC 6803) and one of marine origin (Synechococcus sp. Strain PCC 7002) (Robert Gordon University, Aberdeen). Other work packages were as follows. Genetic manipulations potentially allowed for the expression of a light-driven, Cl−-selective pump in both strains, therefore, enhancing the bioaccumulation of specific ions within the cell (University of Glasgow). Characterisation of surface properties under different salinities (University of Sheffield), ensured that cell–liquid separation efficiency would be maximised post-treatment, as well as monitoring the secretion of mucopolysaccharides in the medium during cell growth. Work at Newcastle University is focused on the social acceptance of this scenario, together with an assessment of the potential risks through the generation and application of a Hazard Analysis and Critical Control Points plan. Finally, researchers in Imperial College (London) designed the process, from biomass production to water treatment and generation of a model photobioreactor. This multimodal approach has produced promising first results, and further optimisation is expected to result in mass scaling of this process

    Bounce cosmology in generalized modified gravities

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    We investigate the bounce realization in the framework of generalized modified gravities arising from Finsler and Finsler-like geometries. In particular, the richer intrinsic geometrical structure is reflected in the appearance of extra degrees of freedom in the Friedmann equations that can drive the bounce. We examine various Finsler and Finsler-like constructions. In the cases of general very special relativity as well as of Finsler-like gravity on the tangent bundle we show that a bounce cannot be easily obtained. However, in the Finsler-Randers space the induced scalar anisotropy can fulfill the bounce conditions and bouncing solutions are easily obtained. Finally, for the general class of theories that include a nonlinear connection a new scalar field is induced, leading to a scalar-tensor structure that can easily drive a bounce. These features reveal the capabilities of Finsler and Finsler-like geometries.Comment: 10 pages, 3 figures, to appear in Univers

    Optimized SU-8 processing for low-cost microstructures fabrication without cleanroom facilities

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    The study and optimization of epoxy-based negative photoresist (SU-8) microstructures through a low-cost process and without the need for cleanroom facility is presented in this paper. It is demonstrated that the Ultraviolet Rays (UV) exposure equipment, commonly used in the Printed Circuit Board (PCB) industry, can replace the more expensive and less available equipment, as the Mask Aligner that has been used in the last 15 years for SU-8 patterning. Moreover, high transparency masks, printed in a photomask, are used, instead of expensive chromium masks. The fabrication of well-defined SU-8 microstructures with aspect ratios more than 20 is successfully demonstrated with those facilities. The viability of using the gray-scale technology in the photomasks for the fabrication of 3D microstructures is also reported. Moreover, SU-8 microstructures for different applications are shown throughout the paper.Work supported by FEDER funds through the Eixo I do Programa Operacional Fatores de Competitividade (POFC) QREN, project reference COMPETE: FCOMP-01-0124-FEDER-020241, and by FCT- Fundação para a Ciência e a Tecnologia, project reference PTDC/EBB-EBI/120334/2010. Vânia C. Pinto thanks the FCT for the SFRH/BD/81526/2011 grant. Paulo J. Sousa thanks the FCT for the SFRH/BD/81562/2011 grant. Vanessa F. Cardoso thanks the FCT for the SFRH/BPD/98109/2013 gran

    Suicide first aid guidelines for Sri Lanka: a Delphi consensus study

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    Background: Sri Lanka has one of the highest suicide rates in the world. Gatekeeper programs aimed at specific target groups could be a promising suicide prevention strategy in the country. The aim of this study was to develop guidelines that help members of the public to provide first aid to persons in Sri Lanka who are at risk of suicide. Methods: The Delphi method was used to elicit consensus on potential helping statements to include in the guidelines. These statements describe information members of the public should have and actions they can take to help a person who is experiencing suicidal thoughts. An expert panel, comprised of mental health and suicide experts in Sri Lanka, rated each statement. The panellists were encouraged to suggest any additional action that was not included in the original questionnaire and, in particular, to include items that were culturally appropriate or gender specific. Responses to open-ended questions were used to generate new items. These items were included in the subsequent Delphi rounds. Three Delphi rounds were carried out. Statements were accepted for inclusion in the guidelines if they were endorsed (rated as essential or important) by at least 80 % of the panel. Statements endorsed by 70–79 % of the panel were re-rated in the following round. Statements with less than 70 % endorsement, or re-rated items that did not receive 80 % or higher endorsement were rejected. Results: The output from the Delphi process was a set of endorsed statements. In the first round questionnaire 473 statements were presented to the panel and 58 new items were generated from responses to the open-ended questions. Of the total 531 statements presented, 304 were endorsed. These statements were used to develop the suicide first aid guidelines for Sri Lanka. Conclusion: By engaging Sri Lankans who are experts in the field of mental health or suicide this research developed culturally appropriate guidelines for providing mental health first aid to a person at risk of suicide in Sri Lanka. The guidelines may serve as a basis for developing training for members of the public to provide mental health first aid to persons at risk of suicide as part of Sri Lanka’s suicide prevention strategy

    A tunable Fabry-Perot optical filter for application in biochemical analysis of human’s fluids

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    This paper reports a Fabry-Perot tunable optical filter for application in clinical analysis, especially to measure the concentration of biochemical substances in biological fluids. Its tunable characteristics enable the measurement of different biochemical substances with the same device. It is composed of two parallel thin silver mirrors with a β-PVDF (Poly(Vinylidene Fluoride) in its β phase) film in-between as the resonance cavity. The filter is tuned by adjusting the space between the mirrors through an electric voltage inducing dipolar orientation in the β-PVDF film. Once the thickness changes of the β-PVDF film is due to variations at a molecular level, the changes are rather homogeneous within the samples. As a result, this approach achieves parallelism between the two mirrors, which is a complex problem to solve in conventional Fabry-Perot optical filters. Moreover, compared with an array of non-tunable optical filters with different cavity lengths, usually used to solve the parallelism problem, this device has a reduced area, its fabrication process is easier and it covers a wider spectral range. In addition, when used as a part of a biological fluids analysis system, it avoids the need for expensive optics and enables low-cost and portable devices, which would improve the use of spectrophotometric analysis in clinical diagnostics.R&D Centro Algoritmi da Universidade do Minho.Escola de Engenharia da Universidade do Minho - program IN2TEC.Fundação para a Ciência e a Tecnologia (FCT) - Grant POCI/CTM/59425/2004

    Microfluidic immunosensor for rapid and highly-sensitive salivary cortisol quantification

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    This paper presents a novel poly(dimethylsiloxane) (PDMS) microfluidic immunosensor that integrates a complementary metal-oxide-semiconductor (CMOS) optical detection system for a rapid and highly-sensitive quantification of salivary cortisol. The simple and non-invasive method of saliva sampling provides an interesting alternative to the blood, allowing a fast sampling at short intervals, relevant for many clinical diagnostic applications. The developed approach is based on the covalent immobilization of a coating antibody (Ab), a polyclonal anti-IgG, onto a treated PDMS surface. The coating Ab binds the capture Ab, an IgG specific for cortisol, allowing its correct orientation. Horseradish peroxidase (HRP)-labelled cortisol is added to compete with the cortisol in the sample, for the capture Ab binding sites. The HRP-labelled cortisol, bonded to the capture Ab, is measured through the HRP enzyme and the tetramethylbenzidine (TMB) substrate reaction. The cortisol quantification is performed by colorimetric detection of HRP-labelled cortisol, through optical absorption at 450 nm, using a CMOS silicon photodiode as the photodetector. Under the developed optimized conditions presented here, e.g., microfluidic channels geometry, immobilization method and immunoassay conditions, the immunosensor shows a linear range of detection between 0.01-20 ng/mL, a limit of detection (LOD) of 18 pg/mL and an analysis time of 35 min, featuring a great potential for point-of-care applications requiring continuous monitoring of the salivary cortisol levels during a circadian cycle.FCT with the reference project UID/EEA/04436/2013, by FEDER funds through the COMPETE 2020 – Programa Operacional Competitividade e Internacionalização (POCI) with the reference project POCI-01-0145-FEDER-006941. V C Pinto thanks the FCT for the SFRH/BD/81526/2011 PhD grant. P J Sousa thanks the FCT for the SFRH/BD/81562/2011 PhD grant. S.O. Catarino thanks the FCT for the SFRH/BPD/108889/2015 grant, supported by national funds from Ministérios da Ciência, Tecnologia e Ensino Superior and by FSE through the POCH - Programa Operacional Capital Humanoinfo:eu-repo/semantics/publishedVersio

    Biosystem with 16 highly selective optical channels for biological fluids analysis in the visible spectrum

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    This paper reports a biosystem (biological system) for analyzing biochemical substances in biological fluids. Rather than one channel, it comprises 16 highly selective optical channels that enable the measurement of the concentration of 16 different biochemical substances. An array of 16 optical filters with high reflectivity and low absorption loss has been designed using dielectric films. Each filter is sensitive in a single wavelength with a FWHM (Full Width Half Maximum) 52%. A commercially available band pass optical filter with a band pass wavelength in 450 600 nm is used to enable the use of a white light source for biosystem illumination. Preliminary tests with a single channel are successfully demonstrated.Fundação para a Ciência e a Tecnologia (FCT) - SFRH/BD/1281/2000, POCTI/33747/ESE/ /1999), FEDER
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