Genealogies and spiritualities in Genesis 4:17-22, 4:25-26, 5:1-32

The three genealogies in Genesis 4:17-22, 4:25-26 en 5:1-32 show different intentions: the first wants (amongst other purposes) to give an aetiology of the trades; the second wants to stress the importance of a new beginning; the third wants to relate Adam to Noah. Each of these approaches to genealogy has a different intent; each wants to indicate a different aspect of God’s care. Each thus evidences an own (though not unrelated) configuration of faith experienced, that is, a different spirituality

Spirituality: Sense And Gist. On Meaning, God And Being

The definition of spirituality is a notoriously difficult undertaking. Rather than continuingly pointing this out, two advances are suggested in this article: That the impossibility of a precise definition of spirituality is accepted, as is the case with many other important aspects of life, and that the inherently paradoxical nature of spirituality is more fully explored as a way of coming to a deeper understanding of this phenomenon. The latter is illustrated by briefly juxtaposing the concepts of God and non-God and of self-implication and estrangement. The most important books for furthering such analyses are listed

Isaac multiplex: Genesis 22 in a new historical representation

In this paper, a new interpretation of the Genesis 22:1-19 account is offered. Based on the new view of biblical historiography as anecdotal (Frykenberg), and drawing on the author's own recent studies on the historical problems related to, and historicallysensitive narratological interpretative possibilities of, this Genesis text, a new meaning and a new dating for Genesis 22:1-19 are concluded to. This text, namely, reflects the end of a struggle for dominance between the different tradents of the patriarchal traditions, in which the Abraham tradents finally subjugate, with this Genesis 22*-text, the Isaac tradents. This occurs late in the compositional history of the Pentateuch, namely between 400 and 250 BCE. HTS Theological Studies Vol. 64 (2) 2008: pp. 907-91

Why the fuss over Brown’s The Da Vinci code? The dynamism of 'icons' and the in/stability of meaning

Dan Brown’s book, “The Da Vinci code” (2003) and the sub-sequent motion picture by the same title (2006), have created a considerable stir within, but not limited to, Christian circles. The cause of the controversy is that, despite Brown’s overt pre-sentation of this work as fiction, it draws on figures, events and themes regarded in religious circles as sacred – most par-ticularly in Christian circles. Holy figures, events and themes are sensitive matters to believers: the meanings attached to them are regarded as essentially fixed, with connotations of perma-nence and eternity. Literature of many kinds, however, reinter-pret set meanings, loosening their perceived inflexibility, thus opening up a dynamism quite foreign to popular notions of definite meaning

Hide and Seek. Aspects of the dynamics of bible translation 1

Art may be viewed as fetish, in that it forces meaning on a chaotic world — a dynamic which is briefly illustrated in this article by means of Pablo Picasso’s famous painting, Les Demoiselles d’Avignon. Similarly, translations of the biblical texts, which result from very complex processes, may be viewed as fetishes. Translation thus requires a process of deducing and reducing meaning from relative chaos. A proper view of the nature of the Bible text and the theoretical load of exegetical and translation activities must becultivated among lay translation users, particularly in our age of rising fundamentalisms. To this end, five suggestions are offered. This view affords Bible translators a more balanced status, namely one of humanity with dignity, than is at times found in some popular circles which regard Bible translators with severe suspicion

The strange case of the patriarchs in Jeremiah 33:26

Jeremiah 33:26 presents a number of interpretational questions, including the relationship of the Jeremiah 33:23-26 pericope with its textual surroundings; the compositional integrity of this pericope; the possible intentions of this passage, and the curious reference to the patriarchs – also with the name of Isaac spelt unusually. The unexpected reference to the patriarchs, in this instance, is of particular concern, since it has direct bearing on a new understanding of the patriarchs in history and text that the author has been developing. Why would the Old Testament patriarchs, so rarely referred to outside the Pentateuch, surface in this particular prophetic text? This article explores these issues, also as they relate to the author’s theory-indevelopment on the patriarchs of Israel

“Give us this day our daily bread” – Clergy’s lived religion in Pretoria central areas

The aim of this article is to reflect on how clergy, working in Pretoria central areas, live out (the external dimension) and experience (the internal dimension) their faith in their everyday life. Thirteen clergy were briefly interviewed on an individual basis and then asked to keep a diary for two months. Four of the interviewed clergy completed the diary project. Based on the interviews and the diaries, the main themes that could be identified in relation to faith in their everyday lives, are responding to the challenges associated with urban ministry, including poverty and trauma, and dealing with the sometimes overwhelming experience of stress that the demands of this ministry can create. Distancing from the different aspects of their tasks, attending to personal needs, and focusing on individual experiences of faith are the main identified strategies the participants employ in dealing with the daily pressures they are exposed to

Long-Acting Cabotegravir and Rilpivirine after Oral Induction for HIV-1 Infection.

BACKGROUND: Long-acting injectable regimens may simplify therapy for patients with human immunodeficiency virus type 1 (HIV-1) infection. METHODS: We conducted a phase 3, randomized, open-label trial in which adults with HIV-1 infection who had not previously received antiretroviral therapy were given 20 weeks of daily oral induction therapy with dolutegravir-abacavir-lamivudine. Participants who had an HIV-1 RNA level of less than 50 copies per milliliter after 16 weeks were randomly assigned (1:1) to continue the current oral therapy or switch to oral cabotegravir plus rilpivirine for 1 month followed by monthly injections of long-acting cabotegravir plus rilpivirine. The primary end point was the percentage of participants who had an HIV-1 RNA level of 50 copies per milliliter or higher at week 48 (Food and Drug Administration snapshot algorithm). RESULTS: At week 48, an HIV-1 RNA level of 50 copies per milliliter or higher was found in 6 of 283 participants (2.1%) who received long-acting therapy and in 7 of 283 (2.5%) who received oral therapy (adjusted difference, -0.4 percentage points; 95% confidence interval [CI], -2.8 to 2.1), a result that met the criterion for noninferiority for the primary end point (margin, 6 percentage points). An HIV-1 RNA level of less than 50 copies per milliliter at week 48 was found in 93.6% who received long-acting therapy and in 93.3% who received oral therapy (adjusted difference, 0.4 percentage points; 95% CI, -3.7 to 4.5), a result that met the criterion for noninferiority for this end point (margin, -10 percentage points). Of the participants who received long-acting therapy, 86% reported injection-site reactions (median duration, 3 days; mild or moderate severity, 99% of cases); 4 participants withdrew from the trial for injection-related reasons. Grade 3 or higher adverse events and events that met liver-related stopping criteria occurred in 11% and 2%, respectively, who received long-acting therapy and in 4% and 1% who received oral therapy. Treatment satisfaction increased after participants switched to long-acting therapy; 91% preferred long-acting therapy at week 48. CONCLUSIONS: Therapy with long-acting cabotegravir plus rilpivirine was noninferior to oral therapy with dolutegravir-abacavir-lamivudine with regard to maintaining HIV-1 suppression. Injection-site reactions were common. (Funded by ViiV Healthcare and Janssen; FLAIR ClinicalTrials.gov number, NCT02938520.)

Evaluation of a strict protocol approach in managing women with severe disease due to hypertension in pregnancy: A before and after study

BACKGROUND: To evaluate whether the introduction of a strict protocol based on the systemic evaluation of critically ill pregnant women with complications of hypertension affected the outcome of those women. METHOD: Study group: Indigent South African women managed in the tertiary hospitals of the Pretoria Academic Complex. Since 1997 a standard definition of women with severe acute maternal morbidity (SAMM), also referred to as a Nearmiss, has been used in the Pretoria Academic Complex. All cases of SAMM and maternal deaths (MD) were entered on the Maternal Morbidity and Mortality Audit System programme (MaMMAS). A comparison of outcome of severely ill women who had complications of hypertension in pregnancy was performed between 1997–1998 (original protocol) and 2002–2003 (strict protocol). Data include women referred from outside the Pretoria Academic Complex area to the tertiary hospitals. RESULTS: Between 1997–1998 there were 79 women with SAMM and 18 maternal deaths due to complications of hypertension, compared with 91 women with SAMM and 13 maternal deaths in 2002–2003. The mortality index (MI) declined from 18.6% to 12.5% (OR 0.62, 95% CI 0.27–1.45). Statistically significant fewer women had renal failure (RR 0.37, 95% CI 0.21 – 0.66) and cerebral complications (RR 0.52, 95%CI 0.34 – 0.81) during the second period, and liver dysfunction (RR 0.27 95%CI 0.06 – 1.25) tended to be lower. However, there tended to be an increase in the number of women, who had immune system failure (RR 4.2 95%CI 0.93 – 18.94) and respiratory failure (RR 1.42 95%CI 0.88 – 2.29) although it did not reach significance. Cardiac failure remained constant (RR 0.84 95%CI 0.54 – 1.30). CONCLUSION: The strict protocol approach based on the systemic evaluation of severely ill pregnant women with complications of hypertension and an intensive, regular feedback mechanism has been associated with a reduction in the number of patients with renal failure and cerebral compromise