Using Caregiver Strain to Predict Participation in a Peer-Support Intervention for Parents of Children With Emotional or Behavioral Needs

Children receiving services for severe emotional and behavioral difficulties are less likely to have parents who are involved in their education and support services. Peer-to-peer family support programs are one approach to increasing the self-efficacy and empowerment of parents’ engagement in the treatment of a child’s mental health conditions. Furthermore, programs providing parental support may reduce the strain and negative consequences caregivers may experience due to the stress of caring for a child with emotional and behavioral needs. Although much is known about the relation between caregivers’ strain and children’s use of mental health services, less is known about caregiver strain and parents’ participation in family support programs. This study evaluated whether caregiver strain predicted parents’ (N = 52) participation in a phone-based, peer-to-peer support intervention. Results of the regression analysis indicated that highly strained parents participated in four to seven more phone conversations over the course of intervention, which occurred across the academic year. Therefore, findings have implications for the school and mental health providers aiming to increase the involvement of parents of children with emotional and behavioral disorders

Using Caregiver Strain to Predict Participation in a Peer-Support Intervention for Parents of Children With Emotional or Behavioral Needs

Children receiving services for severe emotional and behavioral difficulties are less likely to have parents who are involved in their education and support services. Peer-to-peer family support programs are one approach to increasing the self-efficacy and empowerment of parents’ engagement in the treatment of a child’s mental health conditions. Furthermore, programs providing parental support may reduce the strain and negative consequences caregivers may experience due to the stress of caring for a child with emotional and behavioral needs. Although much is known about the relation between caregivers’ strain and children’s use of mental health services, less is known about caregiver strain and parents’ participation in family support programs. This study evaluated whether caregiver strain predicted parents’ (N = 52) participation in a phone-based, peer-to-peer support intervention. Results of the regression analysis indicated that highly strained parents participated in four to seven more phone conversations over the course of intervention, which occurred across the academic year. Therefore, findings have implications for the school and mental health providers aiming to increase the involvement of parents of children with emotional and behavioral disorders

Students at Enrollment Into CommunityBased Systems of Care: Characteristics and Predictors of Functioning in School

Community-based systems of care (SOC) provide a range of services to students with significant emotional and behavioral difficulties and their families. However, little is known about the educational characteristics and functioning of students at enrollment in SOC. The purpose of this study was to replicate and extend previous research by examining the educational characteristics and predictors of school functioning for students referred to SOC using a large and diverse national data source. Participants were 5,628 students ages 6 to 18 years who were enrolled in community-based SOC across 45 U.S. states, districts, and territories. Students’ grades, discipline, and attendance (as reported by caregivers) were used as indicators of school functioning, and students’ demographic characteristics, referral source, and emotional/behavioral functioning were used to predict functioning in school, including the testing of interaction effects. Findings revealed that, although many students earned average grades, a large portion of students had significant discipline and attendance problems. Results of the ordinal regression analyses indicated that most demographic variables and measures of clinical functioning significantly predicted students’ grades, attendance, and discipline, and that age and special education status represented a significant interaction. Findings provide insight into the educational functioning of students at enrollment in community-based SOC and have implications for research and practice

Clinical PhD Graduate Student Views of Their Scientist-Practitioner Training

Objectives: The goal of the scientist-practitioner (S-P) training model is to produce clinical psycholo-gists equipped to integrate and utilize both science and practice in the clinical and research domains. However, much has been written regarding the possible shortcomings of S-P training and whether clinical psychology graduate students are actually gaining the knowledge and skills to integrate sci-ence and practice during graduate training and beyond (Chang, Lee, & Hargreaves, 2008; Gelso, 2006; Merlo, Collins, & Bernstein, 2008; Phillips, 1993). Methods: As such, the present study assessed ratings of satisfaction, perception of ability, and use of the S-P training model within 653 clinical psychology graduate students enrolled in programs that are members of the Council of University Directors of Clinical Psychology. Results: Findings suggest that students are consistently trained in the integration of science and practice and have confidence in their abilities to apply the S-P integra-tion to research and clinical work. However, despite understanding the ways in which science can influence practice, over one third of students reported that they rarely use science-based decisions when informing clients of the clinical services they will be providing. Conclusions: The implications of these results support the need for a more detailed evaluation of clinical psychology graduate stu-dents as well as the use of research-informed practice and the process of providing clients with in-formation they need to make informed choices about treatment

Arabidopsis MSL10 Has a Regulated Cell Death Signaling Activity That Is Separable from Its Mechanosensitive Ion Channel Activity

Members of the MscS superfamily of mechanosensitive ion channels function as osmotic safety valves, releasing osmolytes under increased membrane tension. MscS homologs exhibit diverse topology and domain structure, and it has been proposed that the more complex members of the family might have novel regulatory mechanisms or molecular functions. Here, we present a study of MscS-Like (MSL)10 from Arabidopsis thaliana that supports these ideas. High-level expression of MSL10-GFP in Arabidopsis induced small stature, hydrogen peroxide accumulation, ectopic cell death, and reactive oxygen species- and cell death-associated gene expression. Phosphomimetic mutations in the MSL10 N-terminal domain prevented these phenotypes. The phosphorylation state of MSL10 also regulated its ability to induce cell death when transiently expressed in Nicotiana benthamiana leaves but did not affect subcellular localization, assembly, or channel behavior. Finally, the N-terminal domain of MSL10 was sufficient to induce cell death in tobacco, independent of phosphorylation state. We conclude that the plant-specific N-terminal domain of MSL10 is capable of inducing cell death, this activity is regulated by phosphorylation, and MSL10 has two separable activities-one as an ion channel and one as an inducer of cell death. These findings further our understanding of the evolution and significance of mechanosensitive ion channels

Changes in Transcript, Metabolite, and Antibody Reactivity During the Early Protective Immune Response in Humans to Mycobacterium tuberculosis Infection.

BACKGROUND: Strategies to prevent Mycobacterium tuberculosis (Mtb) infection are urgently required. In this study, we aimed to identify correlates of protection against Mtb infection. METHODS: Two groups of Mtb-exposed contacts of tuberculosis (TB) patients were recruited and classified according to their Mtb infection status using the tuberculin skin test (TST; cohort 1) or QuantiFERON (QFT; cohort 2). A negative reading at baseline with a positive reading at follow-up classified TST or QFT converters and a negative reading at both time points classified TST or QFT nonconverters. Ribonucleic acid sequencing, Mtb proteome arrays, and metabolic profiling were performed. RESULTS: Several genes were found to be differentially expressed at baseline between converters and nonconverters. Gene set enrichment analysis revealed a distinct B-cell gene signature in TST nonconverters compared to converters. When infection status was defined by QFT, enrichment of type I interferon was observed. A remarkable area under the curve (AUC) of 1.0 was observed for IgA reactivity to Rv0134 and an AUC of 0.98 for IgA reactivity to both Rv0629c and Rv2188c. IgG reactivity to Rv3223c resulted in an AUC of 0.96 and was markedly higher compared to TST nonconverters. We also identified several differences in metabolite profiles, including changes in biomarkers of inflammation, fatty acid metabolism, and bile acids. Pantothenate (vitamin B5) was significantly increased in TST nonconverters compared to converters at baseline (q = 0.0060). CONCLUSIONS: These data provide new insights into the early protective response to Mtb infection and possible avenues to interfere with Mtb infection, including vitamin B5 supplementation.Analysis of blood from highly exposed household contacts from The Gambia who never develop latent Mycobacterium tuberculosis infection shows distinct transcriptomic, antibody, and metabolomic profiles compared to those who develop latent tuberculosis infection but prior to any signs of infection

La prensa del Mahyar en Chile: la revista Laiazul (1945)

El presente artículo analiza la importancia de la prensa árabe en el proceso de modernización del Próximo Oriente (ss.XIX y XX), centrando su interés en la prensa de la emigración (Mahyar) de Latinoamérica. Las revistas chilenas El Triunfo (Surilandia, 1930) y Laiazul (Chile, 1945) del intelectual y poeta sirobrasileño Assis Féres, sirven de pretexto para aproximarnos al "arabismo iberoamericano" que ambas revistas propugnan, abriendo nuevas perspectivas de análisis en el discurso literario del Mahyar yanubi.This article analyzes the importance of the Arabic press in the modernization of the Middle East during the 19th and 20th centuries, with special emphasis on the emigrant (Mahyar) press in Latin America. The Chilean journals El Triunfo (Surilandia, 1930) and Laiazul (Chile, 1945) founded by the Sirio-Brazilian poet and intellectual Assis Féres, are examined for the “Ibero-American Arabism” that they defend, leading to new approaches to the analysis of the literary discourse of Mahyar yanûbî