8,350 research outputs found
An experimental test of Rubinstein's bargaining model
This paper offers an experimental test of a version
of Rubinstein’s bargaining model in which the players’ discount
factors are unequal. We find that learning, rationality, and fairness
are all significant in determining the outcome. In particular,
we find that a model of myopic optimization over time predicts
the sign of deviations in the opening proposal from the final
undiscounted agreement in the previous period rather well. To
explain the amplitude of the deviations, we then successfully fit
a perturbed version of the model of myopic adjustment to the
data that allows for a bias toward refusing inequitable offers
Dry Friction due to Adsorbed Molecules
Using an adiabatic approximation method, which searches for Tomlinson
model-like instabilities for a simple but still realistic model for two
crystalline surfaces in the extremely light contact limit, with mobile
molecules present at the interface, sliding relative to each other, we are able
to account for the virtually universal occurrence of "dry friction." The model
makes important predictions for the dependence of friction on the strength of
the interaction of each surface with the mobile molecules.Comment: four pages of latex, figure provide
Velocity weakening and possibility of aftershocks in nanofriction experiments
We study the frictional behavior of small contacts as those realized in the
atomic force microscope and other experimental setups, in the framework of
generalized Prandtl-Tomlinson models. Particular attention is paid to
mechanisms that generate velocity weakening, namely a decreasing average
friction force with the relative sliding velocity.The mechanisms studied model
the possibility of viscous relaxation, or aging effects in the contact. It is
found that, in addition to producing velocity weakening, these mechanisms can
also produce aftershocks at sufficiently low sliding velocities. This provides
a remarkable analogy at the microscale, of friction properties at the
macroscale, where aftershocks and velocity weakening are two fundamental
features of seismic phenomena.Comment: 8 pages, 7 figure
A novel selective 11b-hydroxysteroid dehydrogenase type 1 inhibitor prevents human adipogenesis.
Glucocorticoid excess increases fat mass, preferentially within omental depots; yet circulating cortisol concentrations are normal in most patients with metabolic syndrome (MS). At a pre-receptor level, 11b-hydroxysteroid dehydrogenase type 1 (11b-HSD1) activates cortisol from cortisone locally within adipose tissue, and inhibition of 11b-HSD1 in liver and adipose tissue has been proposed as a novel therapy to treat MS by reducing hepatic glucose output and adiposity. Using a transformed human subcutaneous preadipocyte cell line (Chub-S7) and human primary preadipocytes, we have defined the role of glucocorticoids and 11b-HSD1 in regulating adipose tissue differentiation. Human cells were differentiated with 1.0 mM cortisol (F), or cortisone (E) with or without 100 nM of a highly selective 11b-HSD1 inhibitor PF-877423. 11b-HSD1 mRNA expression increased across adipocyte differentiation (P!0.001, nZ4), which was paralleled by an increase in 11b-HSD1 oxo-reductase activity (from nil on day 0 to 5.9G1.9 pmol/mg per h on day 16,P!0.01, nZ7). Cortisone enhanced adipocyte differentiation; fatty acid-binding protein 4 expression increased 312-fold (P!0.001) and glycerol-3-phosphate dehydrogenase 47-fold (P!0.001) versus controls. This was abolished by co-incubation with PF-877423. In addition, cellular lipid content decreased significantly. These findings were confirmed in the primary cultures of human subcutaneous preadipocytes. The increase in 11b-HSD1 mRNA expression and activity is essential for the induction of human adipogenesis. Blocking adipogenesis with a novel and specific 11b-HSD1 inhibitor may represent a novel approach to treat obesity in patients with MS
Infiltration and short-term movement of nitrogen in a silt-loam soil typical of rice cultivation in Arkansas
Rice production in Arkansas is one of the top three crop commodities in terms of cash receipts. Researchers and farmers report that nitrogen (N) needs to be managed according to a variety of factors with two important ones being soil and fertilizer type. The objectives of this experiment were to determine: 1) the degree to which floodwater-incorporated N applied as urea or as ammonium sulfate infiltrates intact cores (7.2-cm dia., 10-cm depth) containing DeWitt siltloam soil, and 2) the distribution of N during 12 h of ponding. Inorganic-N concentrations were analyzed at 2-cm depth intervals in cores following removal of the flood. Nitrogen from applied fertilizer was recovered as ammonium. Ammonium sulfate-N remained in the top 4 cm of soil with concentrations of 375 µg N g-1 in the surface 2 cm and 300 µg N g-1 at the 2 - 4 cm depth after 12 hr of ponding. At all depth intervals below 4 cm, ammonium sulfate-N remained below 30 µg N g-1. In contrast, after 12 h of ponding, N in soil receiving urea was 105 µg N g-1 in the top 2 cm and 173 µg N g-1 at 2-4 cm. At 4-6, 6-8, and 8-10 cm, N was 109, 108, and 35 µg N g-1, respectively, after 12 h of ponding. These results demonstrate immediate and deeper movement of ammonium into silt loam soil receiving urea as compared to ammonium sulfate, demonstrating how the form of N in fertilizer affects its movement into the soil profile
Local spectroscopy and atomic imaging of tunneling current, forces and dissipation on graphite
Theory predicts that the currents in scanning tunneling microscopy (STM) and
the attractive forces measured in atomic force microscopy (AFM) are directly
related. Atomic images obtained in an attractive AFM mode should therefore be
redundant because they should be \emph{similar} to STM. Here, we show that
while the distance dependence of current and force is similar for graphite,
constant-height AFM- and STM images differ substantially depending on distance
and bias voltage. We perform spectroscopy of the tunneling current, the
frequency shift and the damping signal at high-symmetry lattice sites of the
graphite (0001) surface. The dissipation signal is about twice as sensitive to
distance as the frequency shift, explained by the Prandtl-Tomlinson model of
atomic friction.Comment: 4 pages, 4 figures, accepted at Physical Review Letter
Microbial biomass and nitrogen availability under the invasive plant species Lonicera japonica and native grasses in wetland soil
Invasive plants decrease aboveground biodiversity and suitable wildlife habitat. Wetlands are especially valuable ecosystems because they provide habitat, floodwater control, and function as filters for urban runoff. Wetland soils also act as sinks for nutrients. This characteristic reduces levels of excess nutrients often found in adjacent aquatic systems. The importance of soil functions in wetlands necessitates further investigation of the effects of invasive species on belowground nutrient pools. Approximately 75% of a small neighborhood wetland located in Fayetteville, Ark., has been invaded by Lonicera japonica. The effects of L. japonica and its replacement with native grasses on soil microbial biomass and nutrient pools were evaluated. Eight plots were established in April 2003. Four were left vegetated with the invasive species L. japonica while the other four were revegetated with transplants of five native grass species: Andropogon gerardii, Schizachyrium spp., Sorghastrum nutans, Panicum virgatum, and Tripsacum dactyloides. Soil samples were taken three times over the growing season, once prior to the removal of L. japonica and twice after transplanting occurred. Microbial biomass, soil carbon and nitrogen, Mehlich III- extractable phosphorus, pH, moisture content, and inorganic nitrogen were analyzed and significance was tested using a one-way ANOVA test (
Static and Dry Friction due to Multiscale Surface Roughness
It is shown on the basis of scaling arguments that a disordered interface
between two elastic solids will quite generally exhibit static and "dry
friction" (i.e., kinetic friction which does not vanish as the sliding velocity
approaches zero), because of Tomlinson model instabilities that occur for small
length scale asperities. This provides a possible explanation for why static
and "dry" friction are virtually always observed, and superlubricity almost
never occurs
Risk factors for vulnerable youth in urban townships in South Africa: the potential contribution of reactive attachment disorder
Reactive attachment disorder (RAD) is a psychiatric disorder developing in early or middle childhood as a consequence of significant failures in the caregiving environment. RAD results in children failing to relate socially, either by exhibiting markedly inhibited behaviour or by indiscriminate social behaviour and is associated with significant socio-behavioural problems in the longer term. This study examined RAD in South Africa, a setting with high environmental risks.
We recruited a sub-sample of 40 10-year-old children from a cohort enrolled during pregnancy for whom early attachment status was known. Children were purposefully selected to represent the four attachment categories using the data available on the strange situation procedure (SSP) at 18 months. The Manchester Child Attachment Story Task (MCAST) assessed current attachment and RAD was diagnosed using a standardised assessment package. A high proportion of the children (5/40% or 12.5%) fulfilled diagnostic criteria for RAD; all were boys and were displaying the disinhibited type. SSP classification at 18 months was not significantly associated with RAD symptoms at age of 10 years, while current MCAST classifications were. This suggests that children in this sample are at much higher risk of RAD than in high-income populations, and despite a fairly typical attachment distribution in this population at 18 months, RAD was evidenced in later childhood and associated with current attachment disorganisation.
The strengths of this research include its longitudinal nature and use of diagnostic assessments. Given increasing evidence that RAD is relatively stable over time and introduces longer term socio-behavioural risks; the high rate of RAD in this sample (12.5%) highlights potential developmental threats to children in low- and middle-income countries (LMICs). Our results should be interpreted with caution given sample size and risk of selection bias. Further research is needed to confirm these findings
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