Supersymmetry and Gravitational Duality

We study how the supersymmetry algebra copes with gravitational duality. As a playground, we consider a charged Taub-NUT solution of D=4, N=2 supergravity. We find explicitly its Killing spinors, and the projection they obey provides evidence that the dual magnetic momenta necessarily have to appear in the supersymmetry algebra. The existence of such a modification is further supported using an approach based on the Nester form. In the process, we find new expressions for the dual magnetic momenta, including the NUT charge. The same expressions are then rederived using gravitational duality.Comment: 23 pages, no figures; v2: sign typos fixed in Section 6; v3: version to appear in PRD. Improved discussion in section 5 (on the surface NUT charges) and in section 6 (on the superalgebra

Monorail/Foxa2 regulates floorplate differentiation and specification of oligodendrocytes, serotonergic raphe neurones and cranial motoneurones

In this study, we elucidate the roles of the winged-helix transcription factor Foxa2 in ventral CNS development in zebrafish. Through cloning of monorail (mol), which we find encodes the transcription factor Foxa2, and phenotypic analysis of mol(-/-) embryos, we show that floorplate is induced in the absence of Foxa2 function but fails to further differentiate. In mol(-/-) mutants, expression of Foxa and Hh family genes is not maintained in floorplate cells and lateral expansion of the floorplate fails to occur. Our results suggest that this is due to defects both in the regulation of Hh activity in medial floorplate cells as well as cell-autonomous requirements for Foxa2 in the prospective laterally positioned floorplate cells themselves. Foxa2 is also required for induction and/or patterning of several distinct cell types in the ventral CNS. Serotonergic neurones of the raphe nucleus and the trochlear motor nucleus are absent in mol(-/-) embryos, and oculomotor and facial motoneurones ectopically occupy ventral CNS midline positions in the midbrain and hindbrain. There is also a severe reduction of prospective oligodendrocytes in the midbrain and hindbrain. Finally, in the absence of Foxa2, at least two likely Hh pathway target genes are ectopically expressed in more dorsal regions of the midbrain and hindbrain ventricular neuroepithelium, raising the possibility that Foxa2 activity may normally be required to limit the range of action of secreted Hh proteins

Counting supersymmetric branes

Maximal supergravity solutions are revisited and classified, with particular emphasis on objects of co-dimension at most two. This class of solutions includes branes whose tension scales with g_s^{-\sigma} for \sigma>2. We present a group theory derivation of the counting of these objects based on the corresponding tensor hierarchies derived from E11 and discrete T- and U-duality transformations. This provides a rationale for the wrapping rules that were recently discussed for \sigma<4 in the literature and extends them. Explicit supergravity solutions that give rise to co-dimension two branes are constructed and analysed.Comment: 1+33 pages. To the memory of Laurent Houart. v2: Published version with added reference

Hidden Symmetries and Dirac Fermions

In this paper, two things are done. First, we analyze the compatibility of Dirac fermions with the hidden duality symmetries which appear in the toroidal compactification of gravitational theories down to three spacetime dimensions. We show that the Pauli couplings to the p-forms can be adjusted, for all simple (split) groups, so that the fermions transform in a representation of the maximal compact subgroup of the duality group G in three dimensions. Second, we investigate how the Dirac fermions fit in the conjectured hidden overextended symmetry G++. We show compatibility with this symmetry up to the same level as in the pure bosonic case. We also investigate the BKL behaviour of the Einstein-Dirac-p-form systems and provide a group theoretical interpretation of the Belinskii-Khalatnikov result that the Dirac field removes chaos.Comment: 30 page

G+++ Invariant Formulation of Gravity and M-Theories: Exact BPS Solutions

We present a tentative formulation of theories of gravity with suitable matter content, including in particular pure gravity in D dimensions, the bosonic effective actions of M-theory and of the bosonic string, in terms of actions invariant under very-extended Kac-Moody algebras G+++. We conjecture that they host additional degrees of freedom not contained in the conventional theories. The actions are constructed in a recursive way from a level expansion for all very-extended algebras G+++. They constitute non-linear realisations on cosets, a priori unrelated to space-time, obtained from a modified Chevalley involution. Exact solutions are found for all G+++. They describe the algebraic properties of BPS extremal branes, Kaluza-Klein waves and Kaluza-Klein monopoles. They illustrate the generalisation to all G+++ invariant theories of the well-known duality properties of string theories by expressing duality as Weyl invariance in G+++. Space-time is expected to be generated dynamically. In the level decomposition of E8+++ = E11, one may indeed select an A10 representation of generators Pa which appears to engender space-time translations by inducing infinite towers of fields interpretable as field derivatives in space and time.Comment: Latex 45 pages, 1 figure. Discussion on pages 19 and 20 altered. Appendix B amplified. 4 footnotes added. 2 references added. Acknowledgments updated. Additional minor correction

A Remark on the Renormalization Group Equation for the Penner Model

It is possible to extract values for critical couplings and gamma_string in matrix models by deriving a renormalization group equation for the variation of the of the free energy as the size N of the matrices in the theory is varied. In this paper we derive a ``renormalization group equation'' for the Penner model by direct differentiation of the partition function and show that it reproduces the correct values of the critical coupling and gamma_string and is consistent with the logarithmic corrections present for g=0,1.Comment: LaTeX, 5 pages, LPTHE-Orsay-94-5

Intersection rules, dynamics and symmetries

We consider theories containing gravity, at most one dilaton and form field strengths. We show that the existence of particular BPS solutions of intersecting extremal closed branes select the theories, which upon dimensional reduction to three dimensions possess a simple simply laced Lie group symmetry G. Furthermore these theories can be fully reconstructed from the dynamics of such branes and of their openings. Amongst such theories are the effective actions of the bosonic sector of M-theory and of the bosonic string. The BPS intersecting brane solutions form representations of a subgroup of the group of Weyl reflections and outer automorphisms of the triple Kac-Moody extension G+++ of the G algebra, which cannot be embedded in the overextended Kac-Moody subalgebra G++ characterising the cosmological Kasner solutions.Comment: Latex 30 pages, 3 figure

G2 Dualities in D=5 Supergravity and Black Strings

Five dimensional minimal supergravity dimensionally reduced on two commuting Killing directions gives rise to a G2 coset model. The symmetry group of the coset model can be used to generate new solutions by applying group transformations on a seed solution. We show that on a general solution the generators belonging to the Cartan and nilpotent subalgebras of G2 act as scaling and gauge transformations, respectively. The remaining generators of G2 form a sl(2,R)+sl(2,R) subalgebra that can be used to generate non-trivial charges. We use these generators to generalize the five dimensional Kerr string in a number of ways. In particular, we construct the spinning electric and spinning magnetic black strings of five dimensional minimal supergravity. We analyze physical properties of these black strings and study their thermodynamics. We also explore their relation to black rings.Comment: typos corrected (26 pages + appendices, 2 figures

Abrogation of Stem Loop Binding Protein (Slbp) function leads to a failure of cells to transition from proliferation to differentiation, retinal coloboma and midline axon guidance deficits

Through forward genetic screening for mutations affecting visual system development, we identified prominent coloboma and cell-autonomous retinal neuron differentiation, lamination and retinal axon projection defects in eisspalte (ele) mutant zebrafish. Additional axonal deficits were present, most notably at midline axon commissures. Genetic mapping and cloning of the ele mutation showed that the affected gene is slbp, which encodes a conserved RNA stem-loop binding protein involved in replication dependent histone mRNA metabolism. Cells throughout the central nervous system remained in the cell cycle in ele mutant embryos at stages when, and locations where, post-mitotic cells have differentiated in wild-type siblings. Indeed, RNAseq analysis showed down-regulation of many genes associated with neuronal differentiation. This was coincident with changes in the levels and spatial localisation of expression of various genes implicated, for instance, in axon guidance, that likely underlie specific ele phenotypes. These results suggest that many of the cell and tissue specific phenotypes in ele mutant embryos are secondary to altered expression of modules of developmental regulatory genes that characterise, or promote transitions in, cell state and require the correct function of Slbp-dependent histone and chromatin regulatory genes

Non-commutative Branes from M-theory

The analysis of the worldvolume effective actions of the M-theory Kaluza-Klein monopole and 9-brane suggests that it should be possible to describe non-abelian configurations of M2-branes or M5-branes if the M2-branes are transverse to the eleventh direction and the M5-branes are wrapped on it. This is determined by the fact that the Kaluza-Klein monopole and the M9-brane are constrained to move in particular isometric spacetimes. We show that the same kind of situation is implied by the analysis of the brane descent relations in M-theory. We compute some of the non-commutative couplings of the worldvolume effective actions of these non-abelian systems of M2 and M5 branes and show that they indicate the existence of configurations corresponding to N branes expanding into a higher dimensional M-brane. The reduction to Type II brings up new descriptions of coincident D-branes at strong coupling. We show that these systems have the right non-commutative charges to describe certain expanded configurations playing a role in the framework of the AdS/CFT correspondence. Finally, we discuss the realization of non-commutative brane configurations as topological solitons in non-abelian brane-antibrane systems.Comment: 31 pages, latex file, references adde