Comparison of Prevalence of Synovitis by Ultrasound Assessment in Subjects Exposed or Not to Self-Reported Physical Overexertion: The Monday’s Synovitis

Objective. To compare the proportion of synovitis detected by ultrasonographic study (USS) of the hands, in subjects with no rheumatologic known disease according to self-reported level of overexertion performed the day before. Methods. 407 consecutive volunteers were enrolled in a twelve-month period and underwent an ultrasound assessment of the hand. All studies were performed on Monday or Friday. Subjects were grouped according to their self-reported overexertion carried out the day before. Presence or absence of ultrasonographic findings compatible with synovitis was compared between groups. Results. 95.8% of those tested on Friday had made no overexertion the day before the study, while 30.2% of those assessed on Monday declared to have carried out an overexertion. Presence of carpal synovial hypertrophy, synovial fluid/effusion, and power-Doppler signal was statistically higher in subjects who carried out an overexertion the day before the study than the rest of subjects when the dominant hand was assessed. Globally, presence of any synovitis ultrasonographic finding was statistically higher in subjects who were studied on Monday than Friday (34.9% versus 12.1%) and in subjects who self-reported an overexertion the day before compared to the rest of subjects (47.7 versus 11.5%). Conclusions. In general, we recommend performing the USS as many days as possible after the most recent overexertion

Recomendaciones para el manejo del riesgo cardiovascular en pacientes con artritis reumatoide

Rheumatoid arthritis (RA) is an autoimmune disease primarily known for its joint involvement. However, it is a systemic disease which may potentially affect many other organs. Currently, the impact of RA on cardiovascular risk (CVR) has been demonstrated in multiple studies, both clinical and basic. The purpose of this guide is to enumerate the effects of RA on the cardiovascular system, the impact that RA treatments have on traditional cardiovascular risk factors (CVRF) and to design recommendations for the monitoring and management of such processes on RA patients.La artritis reumatoide (AR) es una enfermedad autoinmune conocida fundamentalmente por su afectación a nivel articular. Sin embargo, se trata de un proceso sistémico con capacidad de afectar muchos otros órganos. Actualmente, el impacto que tiene la AR sobre el riesgo cardiovascular (RCV) ha sido demostrado en múltiples estudios, tanto clínicos como básicos. La más reciente compilación de recomendaciones para el manejo del RCV en pacientes con AR fue publicada en 2010 con bibliografía publicada hasta 2008. El propósito de la presente guía es, en base a los trabajos más recientes, enumerar los efectos que tiene la AR sobre el sistema cardiovascular, la repercusión que tienen los tratamientos de la AR en los factores de riesgo cardiovascular (FRCV) tradicionales y diseñar unas recomendaciones para la vigilancia y manejo de dichos procesos en los pacientes con AR

Subclinical synovitis impact on the progression of lupus joint disease: A 10-year longitudinal multicenter study

ObjectiveTo determine the effect of subclinical synovitis on the progression of joint disease in a cohort of patients with systemic lupus erythematosus over a mean follow-up of 10 years. MethodsA longitudinal follow-up of 96 patients diagnosed with lupus was performed. All patients were considered clinically free of joint disease or with minimal joint impairment at baseline and were studied through ultrasound study of their dominant hand to assess the prevalence of subclinical synovitis. Now, over 10 years after we contacted them and reviewed their evolution to determine the impact of had or had not been diagnosed with subclinical synovitis in their current joint condition. ResultsThirty-one of the 91 reached patients developed clinical progression in their joint manifestations (at least one ordinal degree of worsening). Of these, 23 (74,9%) had demonstrated subclinical synovitis at baseline. In the group of patients who did not progress clinically, 46 (76,6%) did not have this finding at the start of follow-up (p < .01, OR 9,44 95%CI 3,46–25,74). The patients in whom clinical progression was demonstrated had worse combined ultrasound scores than the rest of the patients: 6,41 SD 1,45 vs. 1,15 SD 0,97 (p < .01). ConclusionsThe finding of subclinical synovitis in patients with systemic lupus erythematosus is associated with the development of joint disease progression both clinically and ultrasonographically.SORCOMEuropean university of Madrid (Beca intramural)2.6 Q3 JCR 20220.182 Q2 SJR 2023No data IDR 2023UE