Control of Glycogen Content in Retina: Allosteric Regulation of Glycogen Synthase

Retinal tissue is exceptional because it shows a high level of energy metabolism. Glycogen content represents the only energy reserve in retina, but its levels are limited. Therefore, elucidation of the mechanisms controlling glycogen content in retina will allow us to understand retina response under local energy demands that can occur under normal and pathological conditions. Thus, we studied retina glycogen levels under different experimental conditions and correlated them with glucose-6-phosphate (G-6-P) content and glycogen synthase (GS) activity

Urban futures and the code for sustainable homes

Copyright © 2012 ICE Publishing Ltd. Permission is granted by ICE Publishing to print one copy for personal use. Any other use of these PDF files is subject to reprint fees.A 6?6 ha (66 000 m2) regeneration site, commonly referred to as Luneside East, is to be turned from a run down, economically under-achieving area of Lancaster, UK, into a new, distinctive, vibrant, sustainable quarter of the city. As a result several aspects of water planning for 350 new homes and 8000 m2 of workspace needed to be considered before any infrastructure investment was undertaken. This included assessment of the future capacity requirements (i.e. inflows and outflows) for water infrastructure (i.e. mains water supply, wastewater disposal, rainwater storage and stormwater disposal) much of which will be located underground. This paper looks at the implications of various water management strategies on the Luneside East site (e.g. water-efficient appliances, greywater recycling and rainwater harvesting) in line with current policy measures that focus on technology changes alone (e.g. the code for sustainable homes). Based on these findings this paper outlines some basic implications for technological resilience discussed in the context of four ‘world views’ – that is, the urban futures scenarios considered in this special issue. Conclusions are drawn as to how far this can take engineers, planners and developers in understanding and planning for resilient water infrastructure within a development like Luneside East

Developing a method to build community resilience to climate change in sea change communities

The sea change phenomenon has gained increased attention at all levels of government and in the popular press (eg. formation of the National Sea Change Taskforce, cross-cutting commentary on the Suburbanisation of Coastal Australia in the latest Commonwealth State of Environment Report, and numerous newspaper articles on sea change). Climate change is likely to have dramatic impacts on many of these sea change communities through diminished potable water supplies, rising sea levels, storm surges, and increased intensity of flood events – with indirect impacts on health, financial sectors, and biodiversity. Given the inherent diversity within sea change communities with regard to age, culture, and socio-economic status there are likely to be differences in ways of adapting, the ability to adapt, and the desired direction of any changes. Cognizant of the potential enormity of climate change impacts, the need for rapid responses, and the diversity within communities, this paper proposes a participatory and transformative method to work with communities in responding to climate change and variability. The method focuses on determining probable futures for various communities of place and interest within sea change areas and aims to build the capacity for dynamic on-going learning to achieve those futures, both within and between the communities being studied. Through this process community members may be empowered with dynamic and future-orientated learning skills that build upon community knowledge, innovation, and resilience