Probing quantum nanostructures with near-field optical microscopy and (vice versa)

A theory is presented to show how near-field optical microscopy can be used to probe quantum nanostructures. Calculations are done for a quantum dot. Results for different tip/dot configurations and sizes show that near-field excitation can enhance light-hole transitions, excite selection-rule breaking transitions with rates comparable to allowed transitions, and map electron-hole pair wave functions. Conversely, dot response can be used to characterize tip near-fields.Comment: 8 pages of ReVTex, 5 ps figures, submitted to Appl. Phys. Let

Poly (glycerol adipate) (PGA), an enzymatically synthesized functionalizable polyester and versatile drug delivery carrier : A literature update

The enzymatically synthesized poly (glycerol adipate) (PGA) has demonstrated all the desirable key properties required from a performing biomaterial to be considered a versatile "polymeric-tool" in the broad field of drug delivery. The step-growth polymerization pathway catalyzed by lipase generates a highly functionalizable platform while avoiding tedious steps of protection and deprotection. Synthesis requires only minor purification steps and uses cheap and readily available reagents. The final polymeric material is biodegradable, biocompatible and intrinsically amphiphilic, with a good propensity to self-assemble into nanoparticles (NPs). The free hydroxyl group lends itself to a variety of chemical derivatizations via simple reaction pathways which alter its physico-chemical properties with a possibility to generate an endless number of possible active macromolecules. The present work aims to summarize the available literature about PGA synthesis, architecture alterations, chemical modifications and its application in drug and gene delivery as a versatile carrier. Following on from this, the evolution of the concept of enzymatically-degradable PGA-drug conjugation has been explored, reporting recent examples in the literature.Peer reviewedFinal Published versio

Starbursts and Star Clusters in the Ultraviolet

Hubble Space Telescope ultraviolet (UV) images of nine starburst galaxies reveal them to be highly irregular, even after excluding compact sources (clusters and resolved stars). Most (7/9) are found to have a similar intrinsic effective surface brightnesses, suggesting that a negative feedback mechanism is setting an upper limit to the star formation rate per unit area. All starbursts in our sample contain UV bright star clusters indicating that cluster formation is an important mode of star formation in starbursts. On average about 20% of the UV luminosity comes from these clusters. The brightest clusters, or super star clusters (SSC), are preferentially found at the very heart of starbursts. The size of the nearest SSCs are consistent with those of Galactic globular clusters. The luminosity function of SSCs is well represented by a power law with a slope alpha ~ -2. There is a strong correlation between the far infrared excess and the UV spectral slope. The correlation is well modeled by a geometry where much of their dust is in a foreground screen near to the starburst, but not by a geometry of well mixed stars and dust.Comment: 47 pages, text only, LaTeX with aaspp.sty (version 3.0), compressed postscript figures available at ftp://eta.pha.jhu.edu/RecentPublications/meurer

Microprocessor controlled proof-mass actuator

The objective of the microprocessor controlled proof-mass actuator is to develop the capability to mount a small programmable device on laboratory models. This capability will allow research in the active control of flexible structures. The approach in developing the actuator will be to mount all components as a single unit. All sensors, electronic and control devices will be mounted with the actuator. The goal for the force output capability of the actuator will be one pound force. The programmable force actuator developed has approximately a one pound force capability over the usable frequency range, which is above 2 Hz

Joint for a variable geometry truss and method of constructing same

A joint and a method of constructing a joint for a variable geometry truss having a variable number of planes of variable length battens connected together in a triangular configuration, each plane being connected by six fixed length longerons in a Stewart platform configuration, are presented. The variable length battens allow the orientation of one end plane of the variable geometry truss to be changed to the other end plane in a controlled manner by selectively adjusting the lengths of the variable length battens. A main pivot joint pivotally connects two battens about a pivotal axis. A universal joint is pivotally connected to the main joint such that the pivotal axis of the universal joint is coextensive with the pivotal axis at the main joint. Two longerons are pivotally connected to the universal joint. Each longeron is thereby provided with three intersecting axes of rotation. Each longeron may include a revolute joint, allowing rotation about the longitudinal axis of the longeron

Trends in Concurrency, Polygyny, and Multiple Sex Partnerships During a Decade of Declining HIV Prevalence in Eastern Zimbabwe.

Background. Observed declines in the prevalence of human immunodeficiency virus (HIV) infection in Zimbabwe have been attributed to population-level reductions in sexual partnership numbers. However, it remains unknown whether certain types of sex partnerships were more important to this decline. Particular debate surrounds the epidemiologic importance of polygyny (the practice of having multiple wives). Methods. We analyze changes in reported multiple partnerships, nonmarital concurrency, and polygyny in eastern Zimbabwe during a period of declining HIV prevalence, from 1998 to 2011. Trends are reported for adult men (age, 17–54 years) and women (age, 15–49 years) from 5 survey rounds of the Manicaland HIV/STD Prevention Project, a general-population open cohort study. Results. At baseline, 34.2% of men reported multiple partnerships, 11.9% reported nonmarital concurrency, and 4.6% reported polygyny. Among women, 4.6% and 1.8% reported multiple partnerships and concurrency, respectively. All 3 partnership indicators declined by similar relative amounts (around 60%–70%) over the period. Polygyny accounted for around 25% of male concurrency. Compared with monogamously married men, polygynous men reported higher levels of subsequent divorce/separation (adjusted relative risk [RR], 2.92; 95% confidence interval [CI], 1.87–4.55) and casual sex partnerships (adjusted RR, 1.63; 95% CI, 1.41–1.88). Conclusions. No indicator clearly dominated declines in partnerships. Polygyny was surprisingly unstable and, in this population, should not be considered a safe form of concurrency

The Mid-infrared Fine-structure Lines of Neon as an Indicator of Star For mation Rate in Galaxies

The fine-structure lines of singly ([Ne II] 12.8 micron) and doubly ([Ne III] 15.6 micron) ionized neon are among the most prominent features in the mid-infrared spectra of star-forming regions, and have the potential to be a powerful new indicator of the star formation rate in galaxies. Using a sample of star-forming galaxies with measurements of the fine-structure lines available from the literature, we show that the sum of the [Ne II] and [Ne III] luminosities obeys a tight, linear correlation with the total infrared luminosity, over 5 orders of magnitude in luminosity. We discuss the formation of the lines and their relation with the Lyman continuum luminosity. A simple calibration between star formation rate and the [Ne II]+[Ne III] luminosity is presented.Comment: To appear in ApJ. 8 page

Tunneling mechanism of light transmission through metallic films

A mechanism of light transmission through metallic films is proposed, assisted by tunnelling between resonating buried dielectric inclusions. This is illustrated by arrays of Si spheres embedded in Ag. Strong transmission peaks are observed near the Mie resonances of the spheres. The interaction among various planes of spheres and interference effects between these resonances and the surface plasmons of Ag lead to mixing and splitting of the resonances. Transmission is proved to be limited only by absorption. For small spheres, the effective dielectric constant can be tuned to values close to unity and a method is proposed to turn the resulting materials invisible.Comment: 4 papges, 5 figure