138 research outputs found
Tratamiento quirúrgico de ptosis palpebral miogénica adquirida
Objective: To report the surgical outcome of aponeurosis surgery in patients with acquired myogenic eyelid ptosis and describe surgical guidelines for their correction.
Methods: The clinical records of two patients with acquired myogenic eyelid ptosis after surgical correction were reviewed.
Results: In two patients with acquired myogenic eyelid ptosis and barely good levator function, levator resection surgery was performed. Corneal complications appeared in both cases.
Conclusion: Patients with acquired myogenic eyelid ptosis are at risk of post-operative surgical complications from corneal exposure. Surgical correction should be conservative and performed only when the visual axis is compromise
Effectiveness and safety of the A-H1N1 vaccine in children: a hospital-based case-control study.
Salmonella Biofilm Formation on Aspergillus niger Involves Cellulose – Chitin Interactions
Salmonella cycles between host and nonhost environments, where it can become an active member of complex microbial communities. The role of fungi in the environmental adaptation of enteric pathogens remains relatively unexplored. We have discovered that S. enterica Typhimurium rapidly attaches to and forms biofilms on the hyphae of the common fungus, Aspergillus niger. Several Salmonella enterica serovars displayed a similar interaction, whereas other bacterial species were unable to bind to the fungus. Bacterial attachment to chitin, a major constituent of fungal cell walls, mirrored this specificity. Pre-incubation of S. Typhimurium with N-acetylglucosamine, the monomeric component of chitin, reduced binding to chitin beads by as much as 727-fold and inhibited attachment to A. niger hyphae considerably. A cellulose-deficient mutant of S. Typhimurium failed to attach to chitin beads and to the fungus. Complementation of this mutant with the cellulose operon restored binding to chitin beads to 79% of that of the parental strain and allowed for attachment and biofilm formation on A. niger, indicating that cellulose is involved in bacterial attachment to the fungus via the chitin component of its cell wall. In contrast to cellulose, S. Typhimurium curli fimbriae were not required for attachment and biofilm development on the hyphae but were critical for its stability. Our results suggest that cellulose–chitin interactions are required for the production of mixed Salmonella-A. niger biofilms, and support the hypothesis that encounters with chitinaceous alternate hosts may contribute to the ecological success of human pathogens
The Pierre Auger Observatory Open Data
The Pierre Auger Collaboration has embraced the concept of open access to
their research data since its foundation, with the aim of giving access to the
widest possible community. A gradual process of release began as early as 2007
when 1% of the cosmic-ray data was made public, along with 100% of the
space-weather information. In February 2021, a portal was released containing
10% of cosmic-ray data collected from 2004 to 2018, during Phase I of the
Observatory. The Portal included detailed documentation about the detection and
reconstruction procedures, analysis codes that can be easily used and modified
and, additionally, visualization tools. Since then the Portal has been updated
and extended. In 2023, a catalog of the 100 highest-energy cosmic-ray events
examined in depth has been included. A specific section dedicated to
educational use has been developed with the expectation that these data will be
explored by a wide and diverse community including professional and
citizen-scientists, and used for educational and outreach initiatives. This
paper describes the context, the spirit and the technical implementation of the
release of data by the largest cosmic-ray detector ever built, and anticipates
its future developments.Comment: 19 pages, 8 figure
Radio Measurements of the Depth of Air-Shower Maximum at the Pierre Auger Observatory
The Auger Engineering Radio Array (AERA), part of the Pierre Auger
Observatory, is currently the largest array of radio antenna stations deployed
for the detection of cosmic rays, spanning an area of km with 153
radio stations. It detects the radio emission of extensive air showers produced
by cosmic rays in the MHz band. Here, we report the AERA measurements
of the depth of the shower maximum (), a probe for mass
composition, at cosmic-ray energies between to eV,
which show agreement with earlier measurements with the fluorescence technique
at the Pierre Auger Observatory. We show advancements in the method for radio
reconstruction by comparison to dedicated sets of CORSIKA/CoREAS
air-shower simulations, including steps of reconstruction-bias identification
and correction, which is of particular importance for irregular or sparse radio
arrays. Using the largest set of radio air-shower measurements to date, we show
the radio resolution as a function of energy, reaching a
resolution better than g cm at the highest energies, demonstrating
that radio measurements are competitive with the established
high-precision fluorescence technique. In addition, we developed a procedure
for performing an extensive data-driven study of systematic uncertainties,
including the effects of acceptance bias, reconstruction bias, and the
investigation of possible residual biases. These results have been
cross-checked with air showers measured independently with both the radio and
fluorescence techniques, a setup unique to the Pierre Auger Observatory.Comment: Submitted to Phys. Rev.
Constraining models for the origin of ultra-high-energy cosmic rays with a novel combined analysis of arrival directions, spectrum, and composition data measured at the Pierre Auger Observatory
Ground observations of a space laser for the assessment of its in-orbit performance
The wind mission Aeolus of the European Space Agency was a groundbreaking
achievement for Earth observation. Between 2018 and 2023, the space-borne lidar
instrument ALADIN onboard the Aeolus satellite measured atmospheric wind
profiles with global coverage which contributed to improving the accuracy of
numerical weather prediction. The precision of the wind observations, however,
declined over the course of the mission due to a progressive loss of the
atmospheric backscatter signal. The analysis of the root cause was supported by
the Pierre Auger Observatory in Argentina whose fluorescence detector
registered the ultraviolet laser pulses emitted from the instrument in space,
thereby offering an estimation of the laser energy at the exit of the
instrument for several days in 2019, 2020 and 2021. The reconstruction of the
laser beam not only allowed for an independent assessment of the Aeolus
performance, but also helped to improve the accuracy in the determination of
the laser beam's ground track on single pulse level. The results presented in
this paper set a precedent for the monitoring of space lasers by ground-based
telescopes and open new possibilities for the calibration of cosmic-ray
observatories.Comment: 10 pages, 10 figure
Demonstrating Agreement between Radio and Fluorescence Measurements of the Depth of Maximum of Extensive Air Showers at the Pierre Auger Observatory
We show, for the first time, radio measurements of the depth of shower
maximum () of air showers induced by cosmic rays that are
compared to measurements of the established fluorescence method at the same
location. Using measurements at the Pierre Auger Observatory we show full
compatibility between our radio and the previously published fluorescence data
set, and between a subset of air showers observed simultaneously with both
radio and fluorescence techniques, a measurement setup unique to the Pierre
Auger Observatory. Furthermore, we show radio resolution as a
function of energy and demonstrate the ability to make competitive
high-resolution measurements with even a sparse radio array.
With this, we show that the radio technique is capable of cosmic-ray mass
composition studies, both at Auger and at other experiments.Comment: Submitted to Phys. Rev. Let
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