468 research outputs found

    12-An Archaeological Survey of the Thornapple River Basin in Hastings and Castleton Townships, Barry County, Michigan

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    When the Thornapple Basin Survey program commenced in 1979, the Barry County site files indicated the presence of only 64 archaeological sites in this area of the state. However, it was also quite apparent from the available data in the site files as well as from information provided by the Michigan History Division that no program of systematic archaeological research had ever been conducted in the county. And, clearly, this was a situation that the MHD desired to have remedied. Aside from the interest expressed by the State Archaeologist, Dr. John Halsey, and his staff in having a program of systematic site location survey initiated in the Thornapple River Basin, the senior author, Dr. William Cremin of Western Michigan University, also was anxious to expand WMU\u27s survey activities beyond the nearby Kalamazoo River Basin. After four years of systematic survey in portions of this drainage, Cremin recognized the need for creating a data set for comparison with the growing body of information generated by the Kalamazoo Basin Survey a need which has only increased with the recent completion of this survey program. Now, with a data set derived from more than 350 prehistoric sites occurring in 135 km of the basin surveyed, it has become absolutely essential that comparative information from other drainages in southern Lower Michigan be made available in order that predictive models of prehistoric settlement and subsistence behavior emerging for this universe (and other areas in this portion of the state) might be rigorously tested. With this thought in mind, and responding to the request of MHD that a proposal be submitted for initiating site survey in the Thornapple River Valley, Cremin and his associates began a literature/documents search and examination of the Barry County site files, evaluated the available information, and established a series of research objectives to guide TBS Phase I activities in 1979 as well as to provide a basis for long term systematic survey in this universe in future years

    Spacelab 3: Research in microgravity

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    The Spacelab 3 mission, which focused on research in microgravity, took place during the period April 29 through May 6, 1985. Spacelab 3 was the second flight of the National Aeronautics and Space Administration's modular Shuttle-borne research facility. An overview of the mission is presented. Preliminary scientific results from the mission were presented by investigators at a symposium held at Marshall Space Flight Center on December 4, 1985. This special issue is based on reports presented at that symposium

    Social-ecological systems approach for adaptation to climate change

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    Adaptation to climate change has become part of national development programs (e.g., National Adaptation Planning). Though communities are adapting to climate change across the world, this perspective argues that understanding social and ecological systems requires greater attention to enhance resilience for achieving and moving beyond the Sustainable Development Goals (SDGs) in response to climate change across the world. In addition, based on a systematic literature review, this perspective identifies key research gaps and addresses relevant key challenges and future research direction for social and ecological systems (SES) adaptation to climate change. Ultimately, this may also help move from the existing limits to adaptation (intolerable risks through adaptive actions) concept to social-ecological limits to adaptation and offers an opportunity to integrate adaptation to climate change in development planning by considering both SES

    Teachers as writers: a systematic review

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    This paper is a critical literature review of empirical work from 1990-2015 on teachers as writers. It interrogates the evidence on teachers’ attitudes to writing, their sense of themselves as writers and the potential impact of teacher writing on pedagogy or student outcomes in writing. The methodology was carried out in four stages. Firstly, educational databases keyword searches located 438 papers. Secondly, initial screening identified 159 for further scrutiny, 43 of which were found to specifically address teachers’ writing identities and practices. Thirdly, these sources were screened further using inclusion/exclusion criteria. Fourthly, the 22 papers judged to satisfy the criteria were subject to in-depth analysis and synthesis. The findings reveal that the evidence base in relation to teachers as writers is not strong, particularly with regard to the impact of teachers’ writing on student outcomes. The review indicates that teachers have narrow conceptions of what counts as writing and being a writer and that multiple tensions exist, relating to low self-confidence, negative writing histories, and the challenge of composing and enacting teacher and writer positions in school. However, initial training and professional development programmes do appear to afford opportunities for reformulation of attitudes and sense of self as writer

    Antiretroviral Therapy outcomes among adolescents and youth in rural Zimbabwe

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    Around 2 million adolescents and 3 million youth are estimated to be living with HIV worldwide. Antiretroviral outcomes for this group appear to be worse compared to adults. We report antiretroviral therapy outcomes from a rural setting in Zimbabwe among patients aged 10-30 years who were initiated on ART between 2005 and 2008. The cohort was stratified into four age groups: 10-15 (young adolescents) 15.1-19 years (adolescents), 19.1-24 years (young adults) and 24.1-29.9 years (older adults). Survival analysis was used to estimate rates of deaths and loss to follow-up stratified by age group. Endpoints were time from ART initiation to death or loss to follow-up. Follow-up of patients on continuous therapy was censored at date of transfer, or study end (31 December 2008). Sex-adjusted Cox proportional hazards models were used to estimate hazard ratios for different age groups. 898 patients were included in the analysis; median duration on ART was 468 days. The risk of death were highest in adults compared to young adolescents (aHR 2.25, 95%CI 1.17-4.35). Young adults and adolescents had a 2-3 times higher risk of loss to follow-up compared to young adolescents. When estimating the risk of attrition combining loss to follow-up and death, young adults had the highest risk (aHR 2.70, 95%CI 1.62-4.52). This study highlights the need for adapted adherence support and service delivery models for both adolescents and young adults

    Simple models of the chemical field around swimming plankton

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    Background. Cervical cancer is the fourth most common cancer in women, and we recently reported human leukocyte antigen (HLA) alleles showing strong associations with cervical neoplasia risk and protection. HLA ligands are recognized by killer immunoglobulin-like receptors (KIRs) expressed on a range of immune cell subsets, governing their proinflammatory activity. We hypothesized that the inheritance of particular HLA-KIR combinations would increase cervical neoplasia risk. Methods. Here, we used HLA and KIR dosages imputed from single-nucleotide polymorphism genotype data from 2143 cervical neoplasia cases and 13 858 healthy controls of European decent. Results. The following 4 novel HLA alleles were identified in association with cervical neoplasia, owing to their linkage disequilibrium with known cervical neoplasia-associated HLA-DRB1 alleles: HLA-DRB3*9901 (odds ratio [OR], 1.24; P = 2.49 × 10−9), HLA-DRB5*0101 (OR, 1.29; P = 2.26 × 10−8), HLA-DRB5*9901 (OR, 0.77; P = 1.90 × 10−9), and HLA-DRB3*0301 (OR, 0.63; P = 4.06 × 10−5). We also found that homozygosity of HLA-C1 group alleles is a protective factor for human papillomavirus type 16 (HPV16)-related cervical neoplasia (C1/C1; OR, 0.79; P = .005). This protective association was restricted to carriers of either KIR2DL2 (OR, 0.67; P = .00045) or KIR2DS2 (OR, 0.69; P = .0006). Conclusions. Our findings suggest that HLA-C1 group alleles play a role in protecting against HPV16-related cervical neoplasia, mainly through a KIR-mediated mechanism
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