280 research outputs found
Polarization properties in the transition from below to above lasing threshold in broad-area vertical-cavity surface-emitting lasers
For highly divergent emission of broad-area vertical-cavity surface-emitting
lasers (VCSELs) a rotation of the polarization direction by up to 90 degrees
occurs when the pump rate approaches the lasing threshold. Well below threshold
the polarization is parallel to the direction of the transverse wave vector and
is determined by the transmissive properties of the Bragg reflectors that form
the cavity mirrors. In contrast, near-threshold and above-threshold emission is
more affected by the reflective properties of the reflectors and is
predominantly perpendicular to the direction of transverse wave vectors. Two
qualitatively different types of polarization transition are demonstrated: an
abrupt transition, where the light polarization vanishes at the point of the
transition, and a smooth one, where it is significantly nonzero during the
transition
Self-tuned quantum dot gain in photonic crystal lasers
We demonstrate that very few (1 to 3) quantum dots as a gain medium are
sufficient to realize a photonic crystal laser based on a high-quality
nanocavity. Photon correlation measurements show a transition from a thermal to
a coherent light state proving that lasing action occurs at ultra-low
thresholds. Observation of lasing is unexpected since the cavity mode is in
general not resonant with the discrete quantum dot states and emission at those
frequencies is suppressed. In this situation, the quasi-continuous quantum dot
states become crucial since they provide an energy-transfer channel into the
lasing mode, effectively leading to a self-tuned resonance for the gain medium.Comment: 4 pages, 4 figures, submitted to Phys. Re
Difference between penetration and damping lengths in photonic crystal mirrors
Different mirror geometries in two-dimensional photonic crystal slabs are
studied with fully-vectorial calculations. We compare their optical properties
and, in particular, we show that, for heterostructure mirrors, the penetration
length associated with the delay induced by distributed reflection is not
correlated to the characteristic damping length of the electromagnetic energy
distribution in the mirror. This unexpected result evidences that the usual
trade-off between short damping lengths and large penetration lengths that is
classically encountered in distributed Bragg reflectors can be overcome with
carefully designed photonic crystal structures.Comment: to be published in Applied Physics Letters, 4 pages, 4 figure
Externally mode-matched cavity quantum electrodynamics with charge-tunable quantum dots
We present coherent reflection spectroscopy on a charge and DC Stark tunable
quantum dot embedded in a high-quality and externally mode-matched microcavity.
The addition of an exciton to a single-electron charged quantum dot forms a
trion that interacts with the microcavity just below strong coupling regime of
cavity quantum electrodynamics. Such an integrated, monolithic system is a
crucial step towards the implementation of scalable hybrid quantum information
schemes that are based on an efficient interaction between a single photon and
a confined electron spin.Comment: 10 pages, 4 figure
Propagation of Light in Photonic Crystal Fibre Devices
We describe a semi-analytical approach for three-dimensional analysis of
photonic crystal fibre devices. The approach relies on modal transmission-line
theory. We offer two examples illustrating the utilization of this approach in
photonic crystal fibres: the verification of the coupling action in a photonic
crystal fibre coupler and the modal reflectivity in a photonic crystal fibre
distributed Bragg reflector.Comment: 15 pages including 7 figures. Accepted for J. Opt. A: Pure Appl. Op
High-Frequency Electrooptic Fabry-Perot Modulators
Electrooptic modulators built from GaAs/AlxGa1-xAs Fabry-Perot cavities operating up to 6.5 GHz are reported. The measured frequency response agrees well with the one predicted using an equivalent circuit model derived from high-speed electrical measurements. The parasitic capacitances have been reduced to approximately 30 fF by fabricating the devices on semi-insulating GaAs substrates and integrating them with on-wafer bound pads which have dimensions compatible with microwave coplanar probes
Increased prevalence of the pfdhfr/phdhps quintuple mutant and rapid emergence of pfdhps resistance mutations at codons 581 and 613 in Kisumu, Kenya
<p>Abstract</p> <p>Background</p> <p>Anti-malarial drug resistance in Kenya prompted two drug policy changes within a decade: sulphadoxine-pyrimethamine (SP) replaced chloroquine (CQ) as the first-line anti-malarial in 1998 and artemether-lumefantrine (AL) replaced SP in 2004. Two cross-sectional studies were conducted to monitor changes in the prevalence of molecular markers of drug resistance over the period in which SP was used as the first-line anti-malarial. The baseline study was carried out from 1999-2000, shortly after implementation of SP, and the follow-up study occurred from 2003-2005, during the transition to AL.</p> <p>Materials and methods</p> <p>Blood was collected from malaria smear-positive, symptomatic patients presenting to outpatient centers in Kisumu, Kenya, during the baseline and follow-up studies. Isolates were genotyped at codons associated with SP and CQ resistance. <it>In vitro </it>IC<sub>50 </sub>values for antifolates and quinolones were determined for isolates from the follow-up study.</p> <p>Results</p> <p>The prevalence of isolates containing the <it>pfdhfr </it>N51I/C59R/S108N/<it>pfdhps </it>A437G/K540E quintuple mutant associated with SP-resistance rose from 21% in the baseline study to 53% in the follow-up study (p < 0.001). Isolates containing the <it>pfdhfr </it>I164L mutation were absent from both studies. The <it>pfdhps </it>mutations A581G and A613S/T were absent from the baseline study but were present in 85% and 61%, respectively, of isolates from the follow-up study. At follow-up, parasites with mutations at five <it>pfdhps </it>codons, 436, 437, 540, 581, and 613, accounted for 39% of isolates. The CQ resistance-associated mutations <it>pfcrt </it>K76T and <it>pfmdr1 </it>N86Y rose from 82% to 97% (p = 0.001) and 44% to 76% (p < 0.001), respectively, from baseline to follow-up.</p> <p>Conclusions</p> <p>During the period in which SP was the first-line anti-malarial in Kenya, highly SP-resistant parasites emerged, including isolates harboring <it>pfdhps </it>mutations not previously observed there. SP continues to be widely used in Kenya; however, given the highly resistant genotypes observed in this study, its use as a first-line anti-malarial should be discouraged, particularly for populations without acquired immunity to malaria. The increase in the <it>pfcrt </it>K76T prevalence, despite efforts to reduce CQ use, suggests that either these efforts are not adequate to alleviate CQ pressure in Kisumu, or that drug pressure is derived from another source, such as the second-line anti-malarial amodiaquine.</p
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