Linear spaces with a line-transitive point-imprimitive automorphism group and Fang-Li parameter gcd(k,r) at most eight

In 1991, Weidong Fang and Huiling Li proved that there are only finitely many non-trivial linear spaces that admit a line-transitive, point-imprimitive group action, for a given value of gcd(k,r), where k is the line size and r is the number of lines on a point. The aim of this paper is to make that result effective. We obtain a classification of all linear spaces with this property having gcd(k,r) at most 8. To achieve this we collect together existing theory, and prove additional theoretical restrictions of both a combinatorial and group theoretic nature. These are organised into a series of algorithms that, for gcd(k,r) up to a given maximum value, return a list of candidate parameter values and candidate groups. We examine in detail each of the possibilities returned by these algorithms for gcd(k,r) at most 8, and complete the classification in this case.Comment: 47 pages Version 1 had bbl file omitted. Apologie

Availabilty of emergency care outside working hours in the province of Groningen:The role of E.R. with peripheral hospitals, ambulance services and urgent GP care

In deze rapportage wordt verslag gedaan van een onderzoek naar de bereikbaarheid van de acute zorg in Groningen. De focus lag daarbij op de acute zorg buiten kantooruren: in de avond, nacht en het weekend. Het onderzoek werd uitgevoerd door ARGO Rijksuniversiteit Groningen BV in opdracht van de samenwerkende partijen in de acute zorg, verenigd in het Regionaal Overleg Acute Zorg Groningen (ROAZ)

Steiner t-designs for large t

One of the most central and long-standing open questions in combinatorial design theory concerns the existence of Steiner t-designs for large values of t. Although in his classical 1987 paper, L. Teirlinck has shown that non-trivial t-designs exist for all values of t, no non-trivial Steiner t-design with t > 5 has been constructed until now. Understandingly, the case t = 6 has received considerable attention. There has been recent progress concerning the existence of highly symmetric Steiner 6-designs: It is shown in [M. Huber, J. Algebr. Comb. 26 (2007), pp. 453-476] that no non-trivial flag-transitive Steiner 6-design can exist. In this paper, we announce that essentially also no block-transitive Steiner 6-design can exist.Comment: 9 pages; to appear in: Mathematical Methods in Computer Science 2008, ed. by J.Calmet, W.Geiselmann, J.Mueller-Quade, Springer Lecture Notes in Computer Scienc

Effects of Scavenging, Entrainment, and Aqueous Chemistry on Peroxides and Formaldehyde in Deep Convective Outflow over the Central and Southeast U.S.

Deep convective transport of gaseous precursors to ozone (O3) and aerosols to the upper troposphere is affected by liquid- and mixed-phase scavenging, entrainment of free tropospheric air, and aqueous chemistry. The contributions of these processes are examined using aircraft measurements obtained in storm inflow and outflow during the 2012 Deep Convective Clouds and Chemistry (DC3) experiment combined with high resolution (dx <= 3 km) WRF-Chem simulations of a severe storm, an airmass storm, and a mesoscale convective system (MCS). The simulation results for the MCS suggest that formaldehyde (CH2O) is not retained in ice when cloud water freezes, in agreement with previous studies of the severe storm. By analyzing WRF-Chem trajectories, the effects of scavenging, entrainment, and aqueous chemistry on outflow mixing ratios of CH2O, methyl hydroperoxide (CH3OOH), and hydrogen peroxide (H2O2) are quantified. Liquid-phase microphysical scavenging was the dominant process reducing CH2O and H2O2 outflow mixing ratios in all three storms. Aqueous chemistry did not significantly affect outflow mixing ratios of all three species. In the severe storm and MCS, the higher than expected reductions in CH3OOH mixing ratios in the storm cores were primarily due to entrainment of low background CH3OOH. In the airmass storm, lower CH3OOH and H2O2 scavenging efficiencies (SEs) than in the MCS were partly due to entrainment of higher background CH3OOH and H2O2. Overestimated rain and hail production in WRF-Chem reduces the confidence in ice retention fraction values determined for the peroxides and CH2O

Serotonin and Dopamine Protect from Hypothermia/Rewarming Damage through the CBS/ H2S Pathway

Biogenic amines have been demonstrated to protect cells from apoptotic cell death. Herein we show for the first time that serotonin and dopamine increase H2S production by the endogenous enzyme cystathionine-β-synthase (CBS) and protect cells against hypothermia/rewarming induced reactive oxygen species (ROS) formation and apoptosis. Treatment with both compounds doubled CBS expression through mammalian target of rapamycin (mTOR) and increased H2S production in cultured rat smooth muscle cells. In addition, serotonin and dopamine treatment significantly reduced ROS formation. The beneficial effect of both compounds was minimized by inhibition of their re-uptake and by pharmacological inhibition of CBS or its down-regulation by siRNA. Exogenous administration of H2S and activation of CBS by Prydoxal 5′-phosphate also protected cells from hypothermic damage. Finally, serotonin and dopamine pretreatment of rat lung, kidney, liver and heart prior to 24 h of hypothermia at 3°C followed by 30 min of rewarming at 37°C upregulated the expression of CBS, strongly reduced caspase activity and maintained the physiological pH compared to untreated tissues. Thus, dopamine and serotonin protect cells against hypothermia/rewarming induced damage by increasing H2S production mediated through CBS. Our data identify a novel molecular link between biogenic amines and the H2S pathway, which may profoundly affect our understanding of the biological effects of monoamine neurotransmitters

The Hardness of Code Equivalence over Fq\mathbf{F}_q and its Application to Code-based Cryptography

International audienceThe code equivalence problem is to decide whether two linear codes over F_q are equivalent, that is identical up to a linear isometry of the Hamming space. In this paper, we review the hardness of code equivalence over F_q due to some recent negative results and argue on the possible implications in code-based cryptography. In particular, we present an improved version of the three-pass identification scheme of Girault and discuss on a connection between code equivalence and the hidden subgroup problem