27 research outputs found

    ‘Here to support anybody who needs to come’? An investigation of the provision for EAL pupils in secondary school libraries in England

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    This paper presents the findings of a mixed methods investigation of the effectiveness of provision for EAL pupils by secondary school libraries in England. Data from a quantitative survey of secondary school librarians are triangulated with those of qualitative interviews with staff responsible for EAL provision. A picture emerges of a hybrid environment which addresses a number of the educational, cultural and social needs of EAL learners, but in which a series of barriers to effective provision are also identified. Recommendations are made to key stakeholder groups for the short and long term improvement of EAL provision, and for further research

    Simulation of Cavitating Flows in Diesel Injectors

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    International audienceWith a new two fluid model it is possible to carry out three-dimensional CFD calculations of cavitating flows in hydraulic components of Diesel injection systems. As model geometries a ball valve, a sac-hole nozzle and a one-hole nozzle have been used to test the applicability of the method. Calculations of the ensemble averaged volume fraction show the distribution of cavitation zones. Force calculations were in good agreement with the experiment. With this new tool, the design of new components can be improved

    Luteinizing hormone induces mouse vas deferens protein expression in the murine ovary

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    The aim of our study was to isolate and identify novel proteins that are involved in the process of ovulation. To achieve this goal we used the technique of proteome analysis. Comparison of ovary protein patterns, obtained by high resolution two-dimensional gel electrophoresis from recombinant FSH (rFSH)- and rFSH + human CG (hCG)-treated mice, showed significant differences in protein spot positions and intensities. Subsequent analysis of one of these proteins was performed by mass spectrometry, resulting in the identification of the mouse vas deferens protein (MVDP). MVDP, which was absent in the two-dimensional gel electrophoresis protein pattern of rFSH-primed mice and appeared 3 h aider the hCG surge, is a member of the aldo-keto reductase superfamily and was originally identified in the mouse vas deferens. This is the first study describing MVDP expression and regulation by LH in the ovary. Northern blot analysis of female mice tissues showed that mvdp messenger RNA (mRNA) was only present in adrenal glands and in hCG-treated ovaries. In situ hybridization studies localized the mvdp mRNA unequivocally to ovarian thecal and interstitial cells with an expression profile starting already 1.5 h, and decreasing 24 h, after LH treatment. In the adrenal glands, mvdp mRNA was not regulated by LH and localized in the cells of the zona fasciculata. In murine adrenocortical cells, a recent study proposed a detoxifying role of MVDP, MVDP might fulfill the same function in the ovary; however, because of its strong and early transcriptional induction by LH, it is also possible that MVDP catalyses another important step during the cascade of events occurring at the time of ovulation

    Simulation of Cavitating Flows in Diesel Injectors

    No full text
    With a new two fluid model it is possible to carry out three-dimensional CFD calculations of cavitating flows in hydraulic components of Diesel injection systems. As model geometries a ball valve, a sac-hole nozzle and a one-hole nozzle have been used to test the applicability of the method. Calculations of the ensemble averaged volume fraction show the distribution of cavitation zones. Force calculations were in good agreement with the experiment. With this new tool, the design of new components can be improved
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