Un caso raro de quiste epidermoide plantar bilocular secundario a iatrogenia con extensión al dorso del antepié

ResumenLos quistes epidermoides de la planta del pie son lesiones poco frecuentes que deben distinguirse de otras patologías subcutáneas de localización plantar. Suelen ser por lo general de crecimiento lento, uniloculares y rara vez afectan al dorso del pie. Presentamos un caso de quiste epidermoide plantar bilocular secundario a iatrogenia que se extendió al dorso del antepié. El diagnóstico de sospecha de estas lesiones debe hacerse siempre con el apoyo de pruebas complementarias de imagen y la confirmación diagnóstica siempre se obtiene tras la extirpación quirúrgica y el estudio histopatológico.AbstractEpidermoid cysts of the sole of the foot are quite rare lesions which must be differentiated from other more common subcutaneous pathologies located on the sole. These lesions are usually slow-growing and unilocular and rarely affect the dorsum of the foot. A case of neglected bilocular epidermal cyst lesion located on the sole with invasion the dorsum of the forefoot is presented. Suspected diagnosis of these lesions should be made with the support of additional imaging tests and diagnostic confirmation should always be obtained after surgical removal and subsequent histopathological study

Periodical forcing for the control of chaos in a chemical reaction

Control of the chaotic behavior of a chemical system can be achieved perturbing periodically some control parameters of the system. This procedure based on external forcing, which is based on the phenomenon of resonance, can change a chaotic behavior into a periodical one by means of the application of a sinusoidal perturbation. In this paper, the influence of a periodical modulation added to the parameter controlling the oxygen adsorption rate in a cellular automaton (CA) model studying CO oxidation is analyzed. This CA model considers the oxidation reaction of CO on a catalytic surface, taking into account the catalyst temperature variation in order to analyze the reaction time oscillatory behavior. Simulations of the CA model exhibit chaotic and quasiperiodical behaviors, and it can be shown that the periodical forcing strategy can suppress the chaotic dynamics by means of the stabilization of periodical solutions.Ministerio de Ciencia y Tecnología de España. BFM2003-03986/FISIJunta de Andalucía. FQM-12

Focal plasma cell osteomyelitis: an unusual presentation on the foot

Plasma cellular osteomyelitis is a chronic and recurrent non purulent bone inflammatory entity charactererized by abundance of plasma cells in the lesional bone. Is a recurrent, unifocal or multifocal disorder, which has an unknown etiology with clinical and radiographic features that may make it impossible to distinguish from other non-suppurative sclerosing osteomyelitis. This rare condition usually occurs in metaphysis of a long bone of chil dren or young adults. We report a case of PCO in a 64-year-old woman with intermittent diffused pain in the hal lux of the left foot after several nail avulsions and two surgical procedures on the distal phalanx. The histological study of the bone sample showed reactive sclerotic bone with plasma cells compatible with PCO. In spite of its infectious origin, as in the present case the causal agent is not always identified. Owing to rarity of entity, a clini cal diagnosis is usually not considered and a histopathological examination is essential to establish of a definitive diagnosis

Training Competences in Industrial Risk Prevention with Lego® Serious Play®: A Case Study

This paper proposes the use of the Lego® Serious Play® (LSP) methodology as a facilitating tool for the introduction of competences for Industrial Risk Prevention by engineering students from the industrial branch (electrical, electronic, mechanical and technological engineering), presenting the results obtained in the Universities of Cadiz and Seville in the academic years 2017–2019. Current Spanish legislation does not reserve any special legal attribution, nor does it require specific competence in occupational risk prevention for the regulated profession of a technical industrial engineer (Order CIN 351:2009), and only does so in a generic way for that of an industrial engineer (Order CIN 311:2009). However, these universities consider the training in occupational health and safety for these future graduates as an essential objective in order to develop them for their careers in the industry. The approach is based on a series of challenges proposed (risk assessments, safety inspections, accident investigations and fire protection measures, among others), thanks to the use of “gamification” dynamics with Lego® Serious Play®. In order to carry the training out, a set of specific variables (industrial sector, legal and regulatory framework, business organization and production system), and transversal ones (leadership, teamwork, critical thinking and communication), are incorporated. Through group models, it is possible to identify dangerous situations, establish causes, share and discuss alternative proposals and analyze the economic, environmental and organizational impact of the technical solutions studied, as well as take the appropriate decisions, in a creative, stimulating, inclusive and innovative context. In this way, the theoretical knowledge which is acquired is applied to improve safety and health at work and foster the prevention of occupational risks, promoting the commitment, effort, motivation and proactive participation of the student teams.Spanish Ministry of Science, Innovation and Universities / European Social Fund: Ramón y Cajal contract (RYC-2017-22222

Core regulatory network motif underlies the ocellar complex patterning in Drosophila melanogaster

During organogenesis, developmental programs governed by Gene Regulatory Networks (GRN) define the functionality, size and shape of the different constituents of living organisms. Robustness, thus, is an essential characteristic that GRNs need to fulfill in order to maintain viability and reproducibility in a species. In the present work we analyze the robustness of the patterning for the ocellar complex formation in Drosophila melanogaster fly. We have systematically pruned the GRN that drives the development of this visual system to obtain the minimum pathway able to satisfy this pattern. We found that the mechanism underlying the patterning obeys to the dynamics of a 3-nodes network motif with a double negative feedback loop fed by a morphogenetic gradient that triggers the inhibition in a French flag problem fashion. A Boolean modeling of the GRN confirms robustness in the patterning mechanism showing the same result for different network complexity levels. Interestingly, the network provides a steady state solution in the interocellar part of the patterning and an oscillatory regime in the ocelli. This theoretical result predicts that the ocellar pattern may underlie oscillatory dynamics in its genetic regulation.Junta de Andalucía FQM-122España, Ministerio de Ciencia e Innovación MICINN / MINECOFondos Federales BFU2012-34324Consolider Ingenio-2010 CSD 2007-00

A New Surgical Technique for the Treatment of Retronychia: Proximal Partial Nail Avulsion

[Resumen] La retroniquia u onicocriptosis proximal es una patología que se presenta con relativa frecuencia en las consultas de podología. La avulsión ungueal completa ha sido el tratamiento de elección descrito en la literatura para el abordaje de la patología. A pesar de ser efectiva, no está exenta de inconvenientes asociados a la pérdida de la función mecánica que la lámina ungueal tiene encomendada en el primer dedo de los pies. Para evitar o aminorar la aparición de estos inconvenientes, proponemos una alternativa sencilla consistente en la avulsión parcial proximal no incisional de la lámina ungueal dejando intacta la porción distal adherida al lecho hasta que la nueva lámina ungueal termine por desplazarla.[Abstract] Retronychia or proximal onychocryptosis is a relatively frequent reason for consultation in podiatrics offices. The complete nail avulsion has been the treatment of choice described in the literature for the approach of the pathology. Although this is an effective technic, it is not without drawbacks associated with the loss of the mechanical function that the nail plate has entrusted to the first toe. Toavoid or lessen the appearance of these problems, we propose a simple alternative consisting in partial non-incisional proximal avulsion of the nail plate leaving intact the distal nail portion adhered to the bed until it is displaced by the new nail plate

Periodic forcing on the oscillatory behavior of a reaction simulated by Monte Carlo

In this paper we study the reaction $N_{2}O + H_{2}$ catalyzed on a Ir (110) surface by Monte Carlo simulation (MC), focusing our study on the temporal evolution of the system. The phase diagram of the model, which represents the surface density of adsorbed species as a function of a control parameter, shows three distinct regions: an oscillatory region, which exhibits oscillations P1 (period-1, one maximum), between two stable steady regions. Results obtained are in good agreement with experiments conducted in the reaction. At a later stage and to analyze the stability of the observed P1 oscillations, we apply harmonic disturbances on the MC model. To do this we perturbed the P1 autonomous oscillations by periodic modulation of the partial pressure of one of the reactants. From the perturbed MC model interesting conclusions are drawn: when the external frequency is a half-integer of the natural frequency the behavior becomes aperiodic and quasiperiodic. In view of these results, we can affirm the existence of the Ruelle-Takens-Newhouse route to chaos in the perturbed MC model since it is observed that the chaotic state is obtained by breaking the quasiperiodic state.Ministerio de Ciencia e Innovación (España) FIS2008-0412