Essential Oil of Croton ceanothifolius Baill. Potentiates the Effect of Antibiotics against Multiresistant Bacteria

Submitted by Ana Maria Fiscina Sampaio ([email protected]) on 2020-02-07T16:46:41Z No. of bitstreams: 1 Araújo, Essential....pdf: 480059 bytes, checksum: fae6482a0731dd97886ba0302a211c87 (MD5)Approved for entry into archive by Ana Maria Fiscina Sampaio ([email protected]) on 2020-02-07T16:59:24Z (GMT) No. of bitstreams: 1 Araújo, Essential....pdf: 480059 bytes, checksum: fae6482a0731dd97886ba0302a211c87 (MD5)Made available in DSpace on 2020-02-07T16:59:24Z (GMT). No. of bitstreams: 1 Araújo, Essential....pdf: 480059 bytes, checksum: fae6482a0731dd97886ba0302a211c87 (MD5) Previous issue date: 2020-01-14Regional University of Cariri. Department of Biological Chemistry. Crato, CE, Brazil.Regional University of Cariri. Department of Biological Chemistry. Crato, CE, Brazil.Regional University of Cariri. Department of Biological Chemistry. Crato, CE, Brazil.Regional University of Cariri. Department of Biological Chemistry. Crato, CE, Brazil.Regional University of Cariri. Department of Biological Chemistry. Crato, CE, Brazil.Regional University of Cariri. Department of Biological Chemistry. Crato, CE, Brazil.Regional University of Cariri. Department of Biological Chemistry. Crato, CE, Brazil.Regional University of Cariri. Department of Biological Chemistry. Crato, CE, Brazil.Regional University of Cariri. Department of Biological Chemistry. Crato, CE, Brazil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.Regional University of Cariri. Department of Biological Chemistry. Crato, CE, Brazil.Federal University of Paraná. Curitiba, PR, Brazil.Federal University of Paraná. Curitiba, PR, Brazil.Federal University of Paraná. Curitiba, PR, Brazil.Regional University of Cariri. Department of Biological Chemistry. Crato, CE, Brazil.Milan State University. Department of Agricultural and Environmental Sciences. Milan, Italy.Regional University of Cariri. Department of Biological Chemistry. Crato, CE, Brazil.This study is a pioneer in reporting the antibacterial properties of the species Croton ceanothifolius Baill. The genus Croton belongs to the family Euphorbiaceae composed of numerous species with documented biological activities. However, the pharmacological properties of C. ceanothifolius remain poorly understood. The leaves of this plant were submitted to hydrodistillation for essential oil (CcEO) extraction and the phytochemical characterization of the oil was performed by GC/MS. The minimum inhibitory concentration of the CcEO was determined for the evaluation of antibacterial activity against multiresistant strains of Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli. The antibiotic-modulating activity of the oil, in combination with antibiotics, was also evaluated. The combination of the CcEO with penicillin, norfloxacin, and gentamicin presented a synergistic effect. This effect was more significant for the association with antibiotics of the quinolone and aminoglycoside classes against Escherichia coli. The association of oil with gentamicin showed better results with regard to the Gram-positive strain. The association of the oil with norfloxacin against P. aeruginosa also showed synergism, but the association with penicillin did not change the effect of this antibiotic. Thus, it is concluded that C. ceanothifolius essential oil selectively potentiates the action of antibiotics against multiresistant strains

Manifestações orais associada ao papilomavírus humano (hpv) conceitos atuais: revisão bibliográfica Oral manifestations related to papillomavirus (hpv)

O papilomavírus (HPV) é um DNA vírus do grupo papovavírus, que é altamente transmissível sexualmente, sendo freqüente na região ano-genital e raro na mucosa oral. A sua implantação oral pode ser por auto-inoculação ou pelo contato oro-sexual. As manifestações orais associadas ao HPV são: papiloma, condiloma acuminado, verruga vulgar, hiperplasia epitelial focal, leucoplasias, líquen plano e carcinoma. O diagnóstico é dado pelo exame da lesão e confirmado pela biópsia, com a identificação do tipo de HPV pelas técnicas de biologia molecular (captura híbrida e PCR). O tratamento, dependendo da lesão, pode ser clínico e/ou cirúrgico, obtendo assim a cura clínica, pois o vírus permanece no epitélio da mucosa mesmo após o tratamento.<br>The human papillomavirus (HPV) is a DNA virus, of the papovavirus group, that is highly sexually transmittable. It is common in the anal and genital parts and rarely in the oral mucosa. The oral implantation can be by self-inoculation or by oral-sexual contact. The oral manifestations related to HPV are: papilloma, condyloma acuminatum, verruca vulgaris, focal epithelial hyperplasia, leukoplasia, lichen planus, and the squamous cell carcinoma. The diagnosis is performed by lesion exam and confirmed by biopsy, showing the HPV genotype by molecular biology techniques (hybrid capture and PCR). The treatment, depending on the lesion, can be clinical or surgical, allowing clinical cure, because the virus remains in the epithelium of the mucosa even after the treatment

Produção de biomassa e teor de macronutrientes do milheto, feijão-de-porco e guandu-anão em cultivo solteiro e consorciado Biomass production and macronutrients quantity of millet, jack bean, guandu single and in intercropping

Objetivou-se determinar a produção de biomassa e o teor de macronutrientes do milheto (Pennisetum typhoides (Burm.) Stapf), feijão-de-porco (Canavalia ensiformes (L.) DC.) e guandu-anão (Cajanus cajan (L.) Millsp.) em cultivo solteiro e nos consórcios da gramínea com as leguminosas, visando a produção de palha no sistema plantio direto. O trabalho foi conduzido no campo experimental do Departamento de Agricultura da Universidade Federal de Lavras (Lavras, MG, Brasil). O delineamento foi o de blocos casualizados, com cinco tratamentos e quatro repetições. Apenas o guandu-anão solteiro apresentou menor produção de fitomassa fresca e seca, sendo que os demais tratamentos não diferiram entre si, pelo teste de Tukey a 5% de probabilidade. De forma geral, as leguminosas apresentaram maiores teores de N e Ca e o milheto maiores teores de S. Apenas o feijão-de-porco solteiro apresentou menor teor de P. Os maiores teores de K foram apresentados pelo milheto solteiro e consorciado com as leguminosas e pelo feijão-de-porco em consórcio com milheto. Os menores teores de Mg foram verificados para o guandu-anão.<br>The object of this work was to evaluate the biomass production and the macronutrients quantity of millet (Pennisetum typhoides (Burm.) Stapf), jack bean (Canavalia ensiformes (L.) DC.), guandu (Cajanus cajan, (L.) Millsp.) dwarf cultivar, and the millet with leguminous consortiums to straw production in no-tillage system. The experiment was carried in experimental area at Agriculture Department of the Federal University of Lavras (Lavras, Minas Gerais state, Brazil). The experimental design was randomized blocks, with five treatments and four replications. For biomass production, only the guandu presented smaller fresh and dry biomass yield than the other treatments. In general, the leguminous presented the greatest N and Ca quantities and millet the greatest quantities of S. Only jack bean presented minor P quantity. For K the greatest quantities were verified for single milett and its incropping with leguminous and jack bean in intercroppin with millet. The minor quantities of Mg were observed for guandu

Propriedades físico-hídricas em Latossolo do Cerrado sob diferentes sistemas de manejo Physicohydric properties of Cerrado Latosol under different management systems

Visou-se, neste trabalho, avaliar as propriedades físico-hídricas do solo sob diferentes sistemas de manejo, em comparação com o Cerrado nativo, em Santo Antônio de Goiás, GO, em áreas cultivadas desde o ano de 1993. As propriedades físico-hídricas foram avaliadas nas profundidades de 0-0,10 e 0,10-0,20 m do solo submetido aos sistemas de manejo: S1 (soja/feijão/arroz/milheto/feijão), S2 (soja/milheto/milho), S3 (milho + pastagem de braquiária - integração-lavoura-pecuária) e S4 (cerrado nativo). Utilizou-se, para comparar os resultados obtidos nos diversos sistemas de manejo do solo, o intervalo de confiança com nível de probabilidade de 5%. A área com pastagem de braquiária sob pastejo animal promoveu compactação do solo na camada superficial, verificada pela redução da macroporosidade, aumento da microporosidade e da densidade do solo.<br>The objective of this study was to evaluate the physico-hydric soil properties under different management systems in comparison with the native Cerrado, in Santo Antônio de Goiás, Goiás State, in areas cultivated since 1993. The evaluated systems in the depths of 0 - 0.10 and 0.10 - 0.20 m were: system S1 (soybean/bean/rice/pearl millet /bean), system S2 (soybean/pearl millet/corn), system S3 (corn + Brachiaria brizantha in integrated crop-livestock system) and system S4 (native cerrado). To compare the results obtained in the several soil management systems, the interval of confidence was used, at a probability level of 5%. The use of area under Brachiaria brizantha pasture for animal grazing caused compaction of the soil in the surface layer, verified through the reduction of the macroporosity, and increase of the microporosity and soil bulk density