¿Necesitan los proveedores de servicios de outsourcing una metodología para provisión de servicios?

El mercado de outsourcing ha estado creciendo en los últimos años y se prevé que lo siga haciendo en los próximos, pero este crecimiento ha estado limitado por el fracaso de muchos proyectos que, en algunos casos, han llevado a las organizaciones a asumir de nuevo esos servicios (insourcing). Estos fracasos se han debido en gran parte a los problemas con los proveedores: falta de experiencia, de capacidades para asumir los proyectos, dificultad en la comunicación. Así como hay marcos de buenas prácticas para la gestión de los proyectos de outsourcing para los clientes, no ocurre lo mismo con los proveedores, que basan la provisión de los servicios en sus experiencias anteriores y en sus capacidades técnicas. El objetivo de este artículo es demostrar la necesidad de proponer una metodología que guíe a los proveedores durante todo el ciclo de vida un proyecto de outsourcing y que facilite la provisión de servicios de calidad y bien gestionados. ABSTRACT. The outsourcing market has been growing in recent years and it is expected to keep doing it, but this growth has been limited by the failure of many projects. These failures have been due to a major degree to problems with providers: lack of experience and capacity to take on the projects and difficult communication. There are good practices frameworks for managing outsourcing projects for clients, but it is not the same for providers, who base the provision of services on their past experience and technical capabilities. The aim of this paper is to state the need to propose a methodology that guides providers throughout the whole outsourcing life cycle and facilitates the provision of quality services and their management

¿Necesitan los proveedores de outsourcing una metodología para la provisión de servicios?

El mercado de outsourcing ha estado creciendo en los últimos años y se espera que lo siga haciendo, pero este crecimiento se ha visto limitado por el fracaso de muchos proyectos. Estos fracasos se han debido en gran parte a los problemas con los proveedores: la falta de experiencia y capacidad para asumir los proyectos, y una comunicación difícil. Se han propuesto marcos de buenas prácticas para la gestión de proyectos de outsourcing desde el punto de vista del cliente, pero no ha sido así para los proveedores, que basan la prestación de servicios en su experiencia pasada y sus capacidades técnicas. El objetivo de este trabajo es establecer la necesidad de proponer una metodología que guíe a los proveedores a lo largo de todo el ciclo de vida del outsourcing y facilite la provisión de servicios de calidad y bien gestionados. ABSTRACT. The outsourcing market has been growing in recent years and it is expected to keep doing it, but this growth has been limited by the failure of many projects. These failures have been due to a major degree to problems with providers: lack of experience and capacity to take on the projects and difficult communication. There are good practices frameworks for managing outsourcing projects for clients, but it is not the same for providers, who base the provision of services on their past experience and technical capabilities. The aim of this paper is to state the need to propose a methodology that guides providers throughout the whole outsourcing life cycle and facilitates the provision of quality services and their management

Prácticas de seguridad por diseño para la gestión de proyectos TI en PYMEs

Seguridad por diseño (SbD) es una filosofía orientada a la gestión de proyectos de desarrollo software seguro. Este artículo presenta el resultado de una investigación, en la que las prácticas de SbD son mapeadas con las prácticas, actividades y objetivos de control propuestos por los principales marcos y estándares que tratan la gestión de proyectos para el desarrollo software. Estos marcos se estructuran en los tres niveles organizativos típicos de las organizaciones: estratégico, táctico y operativo. El resultado de la investigación muestra las principales aportaciones y los vacíos que estos marcos tienen en la gestión de los proyectos para el desarrollo de producto software seguro. Además, en el entorno de las PYMEs, este estudio facilita a los profesionales de TI la aplicación de prácticas, actividades, y objetivos de control de seguridad, integrando distintos marcos y estándares de gobernanza y gestión en los proyectos de desarrollo TI

Propuesta de una metodología para gestión de proyectos de outsourcing de TI para proveedores

Los avances tecnológicos actuales que han llevado a una economía globalmente conectada, junto con la creciente tendencia hacia la privatización, globalización y desregulación están dando lugar a nuevos modelos organizativos y a un aumento de la colaboración entre proveedores y clientes, compartiendo información y flujos de proceso. Todo ello ha contribuido directamente a la gran expansión del outsourcing y a que se considere como una herramienta estratégica para las organizaciones. En este entorno y dada la creciente complejidad organizativa, el uso de una metodología para ayudar a la implantación de proyectos de outsourcing se ha convertido en algo casi necesario. En los últimos años se han propuesto algunas metodologías, especialmente para apoyo de las organizaciones cliente de outsourcing, pero no consideramos que sean completas en cuanto a contemplar todos los aspectos necesarios para guiar un proyecto de outsourcing. Es por ello que, en este artículo, proponemos una metodología para gestión de proyectos de outsourcing de TI desde el punto de vista del proveedor que sea completa y fácil de aplicar. Abstract -. Current technological advances that have led to a globally connected economy, together with the increasing trend towards privatization and deregulation, are leading to new organizational models and increased collaboration between suppliers and customers, sharing information and process flows. This has directly contributed to the great expansion of outsourcing, considering it as a strategic tool for organizations. In this environment, and given the increasing organizational complexity, the use of a methodology to assist the implementation of outsourcing projects has become almost necessary. In recent years several methodologies and models have been proposed, especially for supporting client outsourcing organizations, but we do not consider them to be complete, they do not cover all necessary aspects to manage an outsourcing project. That is the reason because we, in this paper, propose a methodology for outsourcing project management from the point of view of the suppliers that was complete and easy to apply

Factores de seguridad por diseño para el desarrollo y evaluación de software seguro = Security by design factors for developing and evaluating secure software

Seguridad por diseño (SbD) es una filosofía orientada a la gestión segura de proyectos de desarrollo software seguro. En este artículo se presenta el resultado de una investigación en la que, partiendo de las prácticas propuestas por SbD, se define una estructura de factores para la gestión segura de proyectos de ingeniería de software. Los factores se estructuran en tres niveles organizativos (estratégico, táctico y operativo) con objeto de facilitar la implantación y evaluación del marco SbD. y han sido mapeados con los marcos y estándares de TI más representativos de los tres niveles organizativos. El resultado muestra las aportaciones y los vacíos de estos marcos para afrontar la seguridad en los proyectos de desarrollo de un producto software seguro

CIBERER : Spanish national network for research on rare diseases: A highly productive collaborative initiative

Altres ajuts: Instituto de Salud Carlos III (ISCIII); Ministerio de Ciencia e Innovación.CIBER (Center for Biomedical Network Research; Centro de Investigación Biomédica En Red) is a public national consortium created in 2006 under the umbrella of the Spanish National Institute of Health Carlos III (ISCIII). This innovative research structure comprises 11 different specific areas dedicated to the main public health priorities in the National Health System. CIBERER, the thematic area of CIBER focused on rare diseases (RDs) currently consists of 75 research groups belonging to universities, research centers, and hospitals of the entire country. CIBERER's mission is to be a center prioritizing and favoring collaboration and cooperation between biomedical and clinical research groups, with special emphasis on the aspects of genetic, molecular, biochemical, and cellular research of RDs. This research is the basis for providing new tools for the diagnosis and therapy of low-prevalence diseases, in line with the International Rare Diseases Research Consortium (IRDiRC) objectives, thus favoring translational research between the scientific environment of the laboratory and the clinical setting of health centers. In this article, we intend to review CIBERER's 15-year journey and summarize the main results obtained in terms of internationalization, scientific production, contributions toward the discovery of new therapies and novel genes associated to diseases, cooperation with patients' associations and many other topics related to RD research

GPS-PYMEs: Marco de Gestión de Proyectos para el desarrollo Seguro en PYMEs

En la actualidad no se concibe una empresa, por pequeña que esta sea, sin algún tipo de servicio TI. Se presenta para cada empresa el reto de emprender proyectos para desarrollar o contratar servicios de TI que soporten los diferentes procesos de negocio de la empresa. Por otro lado, a menos que los servicios de TI estén aislados de toda red, lo cual es prácticamente imposible en la actualidad, no existe un servicio o un proyecto que lo desarrolle garantizando el 100% de seguridad. Así la empresa maneja una dualidad entre desarrollar productos/servicios de TI seguros y el mantenimiento constante de sus servicios TI en estado seguro. La gestión de los proyectos para el desarrollo de los servicios de TI se aborda, en la mayoría de las empresas, aplicando distintas prácticas, utilizadas en otros proyectos y recomendadas, a tal efecto, por marcos y estándares con mayor reconocimiento. Por lo general, estos marcos incluyen, entre sus procesos, la gestión de los riesgos orientada al cumplimiento de plazos, de costes y, a veces, de la funcionalidad del producto o servicio. Sin embargo, en estas prácticas se obvian los aspectos de seguridad (confidencialidad, integridad y disponibilidad) del producto/servicio, necesarios durante el desarrollo del proyecto. Además, una vez entregado el servicio, a nivel operativo, cuando surge algún fallo relativo a estos aspectos de seguridad, se aplican soluciones ad-hoc. Esto provoca grandes pérdidas y, en ocasiones, pone en peligro la continuidad de la propia empresa. Este problema, se va acrecentando cada día más, en cualquier tipo de empresa y, son las PYMEs, por su la falta de conocimiento del problema en sí y la escasez de recursos metodológicos y técnicos, las empresas más vulnerables. Por todo lo anterior, esta tesis doctoral tiene un doble objetivo. En primer lugar, demostrar la necesidad de contar con un marco de trabajo que, integrado con otros posibles marcos y estándares, sea sencillo de aplicar en distintos tipos y envergaduras de proyectos, y que guíe a las PYMEs en la gestión de proyectos para el desarrollo seguro y posterior mantenimiento de la seguridad de sus servicios de TI. En segundo lugar, cubrir esta necesidad desarrollando un marco de trabajo que ofrezca un modelo de proceso genérico aplicable sobre distintos patrones de proyecto y una librería de activos de seguridad que sirva a las PYMEs de guía durante el proceso de gestión del proyecto para el desarrollo seguro. El modelo de proceso del marco propuesto describe actividades en los tres niveles organizativos de la empresa (estratégico, táctico y operativo). Está basado en el ciclo de mejora continua (PDCA) y en la filosofía Seguridad por Diseño, propuesta por Siemens. Se detallan las prácticas específicas de cada actividad, las entradas, salidas, acciones, roles, KPIs y técnicas aplicables para cada actividad. Estas prácticas específicas pueden aplicarse o no, a criterio del jefe de proyecto y de acuerdo al estado de la empresa y proyecto que se quiera desarrollar, estableciendo así distintos patrones de proceso. Para la validación del marco se han elegido dos PYMEs. La primera del sector servicios y la segunda del sector TIC. El modelo de proceso ha sido aplicado sobre un mismo patrón de proyecto que responde a necesidades comunes a ambas empresas. El patrón de proceso ha sido valorado en los proyectos elegidos en ambas empresas, antes y después de su aplicación. Los resultados del estudio, después de su aplicación en ambas empresas, han permitido la validación del patrón de proceso, en la mejora de la gestión de proyecto para el desarrollo seguro de TI en las PYMEs. ABSTRACT Today a company without any IT service is not conceived, even if it is small either. It presents the challenge for each company to undertake projects to develop or contract IT services that support the different business processes of the company. On the other hand, unless IT services are isolated from whole network, which is virtually impossible at present, there is no service or project, which develops guaranteeing 100% security. So the company handles a duality, develop products / insurance IT services and constant maintenance of their IT services in a safe state. The project management for the development of IT services is addressed, in most companies, using different practices used in other projects and recommended for this purpose by frameworks and standards with greater recognition. Generally, these frameworks include, among its processes, risk management aimed at meeting deadlines, costs and, sometimes, the functionality of the product or service. However, safety issues such as confidentiality, integrity and availability of the product / service, necessary for the project, they are ignored in these practices. Moreover, once the service delivered at the operational level, when a fault on these safety issues arise, ad-hoc solutions are applied. This causes great losses and sometimes threatens the continuity of the company. This problem is adding more every day, in any kind of business and SMEs are, by their lack of knowledge of the problem itself and the lack of methodological and technical resources, the most vulnerable companies. For all these reasons, this thesis has two objectives. Firstly demonstrate the need for a framework that integrated with other possible frameworks and standards, it is simple to apply in different types and wingspans of projects, and to guide SMEs in the management of development projects safely, and subsequent maintenance of the security of their IT services. Secondly meet this need by developing a framework that provides a generic process model applicable to project different patterns and a library of security assets, which serve to guide SMEs in the process of project management for development safe. The process model describes the proposed activities under the three organizational levels of the company (strategic, tactical and operational). It is based on the continuous improvement cycle (PDCA) and Security Design philosophy proposed by Siemens. The specific practices, inputs, outputs, actions, roles, KPIs and techniques applicable to each activity are detailed. These specific practices can be applied or not, at the discretion of the project manager and according to the state of the company and project that the company wants to develop, establishing different patterns of process. Two SMEs have been chosen to validate the frame work. The first of the services sector and the second in the ICT sector. The process model has been applied on the same pattern project that responds to needs common to both companies. The process pattern has been valued at the selected projects in both companies before and after application. The results of the study, after application in both companies have enabled pattern validation process, improving project management for the safe development of IT in SMEs

How do women living with HIV experience menopause? Menopausal symptoms, anxiety and depression according to reproductive age in a multicenter cohort

CatedresBackground: To estimate the prevalence and severity of menopausal symptoms and anxiety/depression and to assess the differences according to menopausal status among women living with HIV aged 45-60 years from the cohort of Spanish HIV/AIDS Research Network (CoRIS). Methods: Women were interviewed by phone between September 2017 and December 2018 to determine whether they had experienced menopausal symptoms and anxiety/depression. The Menopause Rating Scale was used to evaluate the prevalence and severity of symptoms related to menopause in three subscales: somatic, psychologic and urogenital; and the 4-item Patient Health Questionnaire was used for anxiety/depression. Logistic regression models were used to estimate odds ratios (ORs) of association between menopausal status, and other potential risk factors, the presence and severity of somatic, psychological and urogenital symptoms and of anxiety/depression. Results: Of 251 women included, 137 (54.6%) were post-, 70 (27.9%) peri- and 44 (17.5%) pre-menopausal, respectively. Median age of onset menopause was 48 years (IQR 45-50). The proportions of pre-, peri- and post-menopausal women who had experienced any menopausal symptoms were 45.5%, 60.0% and 66.4%, respectively. Both peri- and post-menopause were associated with a higher likelihood of having somatic symptoms (aOR 3.01; 95% CI 1.38-6.55 and 2.63; 1.44-4.81, respectively), while post-menopause increased the likelihood of having psychological (2.16; 1.13-4.14) and urogenital symptoms (2.54; 1.42-4.85). By other hand, post-menopausal women had a statistically significant five-fold increase in the likelihood of presenting severe urogenital symptoms than pre-menopausal women (4.90; 1.74-13.84). No significant differences by menopausal status were found for anxiety/depression. Joint/muscle problems, exhaustion and sleeping disorders were the most commonly reported symptoms among all women. Differences in the prevalences of vaginal dryness (p = 0.002), joint/muscle complaints (p = 0.032), and sweating/flush (p = 0.032) were found among the three groups. Conclusions: Women living with HIV experienced a wide variety of menopausal symptoms, some of them initiated before women had any menstrual irregularity. We found a higher likelihood of somatic symptoms in peri- and post-menopausal women, while a higher likelihood of psychological and urogenital symptoms was found in post-menopausal women. Most somatic symptoms were of low or moderate severity, probably due to the good clinical and immunological situation of these women

Discovering HIV related information by means of association rules and machine learning

Acquired immunodeficiency syndrome (AIDS) is still one of the main health problems worldwide. It is therefore essential to keep making progress in improving the prognosis and quality of life of affected patients. One way to advance along this pathway is to uncover connections between other disorders associated with HIV/AIDS-so that they can be anticipated and possibly mitigated. We propose to achieve this by using Association Rules (ARs). They allow us to represent the dependencies between a number of diseases and other specific diseases. However, classical techniques systematically generate every AR meeting some minimal conditions on data frequency, hence generating a vast amount of uninteresting ARs, which need to be filtered out. The lack of manually annotated ARs has favored unsupervised filtering, even though they produce limited results. In this paper, we propose a semi-supervised system, able to identify relevant ARs among HIV-related diseases with a minimal amount of annotated training data. Our system has been able to extract a good number of relationships between HIV-related diseases that have been previously detected in the literature but are scattered and are often little known. Furthermore, a number of plausible new relationships have shown up which deserve further investigation by qualified medical experts

COVID-19 in hospitalized HIV-positive and HIV-negative patients : A matched study

CatedresObjectives: We compared the characteristics and clinical outcomes of hospitalized individuals with COVID-19 with [people with HIV (PWH)] and without (non-PWH) HIV co-infection in Spain during the first wave of the pandemic. Methods: This was a retrospective matched cohort study. People with HIV were identified by reviewing clinical records and laboratory registries of 10 922 patients in active-follow-up within the Spanish HIV Research Network (CoRIS) up to 30 June 2020. Each hospitalized PWH was matched with five non-PWH of the same age and sex randomly selected from COVID-19@Spain, a multicentre cohort of 4035 patients hospitalized with confirmed COVID-19. The main outcome was all-cause in-hospital mortality. Results: Forty-five PWH with PCR-confirmed COVID-19 were identified in CoRIS, 21 of whom were hospitalized. A total of 105 age/sex-matched controls were selected from the COVID-19@Spain cohort. The median age in both groups was 53 (Q1-Q3, 46-56) years, and 90.5% were men. In PWH, 19.1% were injecting drug users, 95.2% were on antiretroviral therapy, 94.4% had HIV-RNA < 50 copies/mL, and the median (Q1-Q3) CD4 count was 595 (349-798) cells/μL. No statistically significant differences were found between PWH and non-PWH in number of comorbidities, presenting signs and symptoms, laboratory parameters, radiology findings and severity scores on admission. Corticosteroids were administered to 33.3% and 27.4% of PWH and non-PWH, respectively (P = 0.580). Deaths during admission were documented in two (9.5%) PWH and 12 (11.4%) non-PWH (P = 0.800). Conclusions: Our findings suggest that well-controlled HIV infection does not modify the clinical presentation or worsen clinical outcomes of COVID-19 hospitalization