The statistical analysis of spatial point patterns

Imperial Users onl

Reparations – An Exploration of Musical Narratives in an Australian Context

This project entailed the composition, recording and production of 8 pieces of music centred around addressing social issues in my home country of Australia through the use of musical narratives. These issues included Australia’s mistreatment of Indigenous Australians and inaction in combating environmental degradation and climate change. Throughout my research in these two areas, the intersectionality of these issues became more clear to me as I delved deeper into the history behind their manifestation in Australia. Throughout my research and composition process, I drew inspiration from a wide range of Australian artistic works including music, literature, photography and visual art, with the goal of creating an interconnected body of work that served the ultimate purpose of inspiring positive social change with regards to systemic racism and environmental degradation in Australia, as well as contributing to the global fight against these forces.https://remix.berklee.edu/graduate-studies-global-jazz/1090/thumbnail.jp

Alien Registration- Byth, Ann L. (Saco, York County)

https://digitalmaine.com/alien_docs/4100/thumbnail.jp

Phenanthrene Synthesis and the Biosynthesis of Mollisin

Mollisin (1) 4.5 is derived via the polyketide pathway in the fungus Mollisia caesia and is the only known natural product to contain an aromatic dichloroacetyl moiety. Since its discovery in 1956 several 50-54 groups have attempted to unravel the biosynthesis of mollisin because of its unique structure. The ultimate aim of the work described in this thesis was to elucidate the biogenesis of this unusual fungal metabolite and is in part a continuation of the work performed 50 by A. A. Finnie 50 in this laboratory. The Introduction gives a brief account of the polyketide pathway and discusses biological chlorination, a common in vivo modification in the biosynthesis of polyketides and other classes of metabolite. The Introduction also describes in detail the mechanism for the formation of phenanthrenes via stilbene photocyclisation. This is relevant to subsequent chapters dealing with synthetic strategies to the phenanthrene derivatives which are postulated intermediates in the biosynthesis of mollisin. Practical aspects of stilbene photocyclisations are outlined in the final section of the Introduction. The biosynthesis of mollisin is discussed in Chapter 1 and is proposed to involve chlorination and then ring degradation of a polyketide derived phenanthrene (14), (15) or (16). Chapter 1 also records the disappointing result of feeding sodium [2-H3, 1-13 C]- acetate to malt agar cultures of M. caesia during the present investigation. Thus it was proposed to study the biosynthesis of mollisin by feeding deuterium labelled phenanthrenes (14) - (16) to the fungal medium. Chapters 2, 3 and 4 describe attempts to synthesise the postulated biosynthetic intermediates. The synthesis, properties and photochemistry of ortho-halostilbenes with alpha'-acetoxy-alpha-cyano or alpha'-acetoxy-alpha-carbomethoxy substituents are recorded in Chapters 2 and 3 respectively. The evidence from the photochemical experiments indicates that an ortho-halo substituent cannot be used to regio-chemically control the cyclisation step in these systems. As outlined in Chapter 3, a significant result was the finding that the 9-carbo-methoxyl group of phenanthrene (173) can be easily removed with simultaneous hydrolysis of the 10-acetoxyl group upon treatment with aqueous base. Chapter 4 mainly deals with attempts to synthesise phenanthrene (14) using benzyl protecting groups for the phenolic substituents in the starting materials. Unfortunately, no feeding experiments employing deuterium labelled phenanthrenes were conducted. However, many interesting results were obtained in connection with the photochemical synthesis of phenanthrenes

The relationship between obesity and self-esteem: longitudinal evidence from Australian adults

We examine whether low self-esteem increases the risk of obesity in a panel of Australian adults. To address the problem of endogeneity, we look at weight changes following exogenous shocks to self-esteem, such as the unexpected death of friends and family members. We find that negative shocks adversely affect self-esteem in turn leading to large increases in weight via increased food consumption and reduced exercise. The effects of the negative shocks were found to be larger for the lower educated and females

Data maturity and follow-up in time-to-event analyses

NHMR

Inheritance of photo-sensitivity in pigeonpea

Pigeonpea [Cajanus cajan (L.) Millsp.] is a short-day legume species and the late maturing genotypes are more photosensitive than early types. To generate information about the inheritance of photo-sensitivity, this study was conducted under natural and artificially extended (16 h) photo-periods using F1, F2 and BC1F1 generations. Under natural photo-period, F1 hybrids showed partial dominance of earliness; while in F2, a normal distribution that was skewed towards earliness was observed. In contrast under extended photo-period, the spread of F2 data was wide with discontinuities recorded at day 70, 82 and 103. Chisquare tests, when applied to F2 and BC1F1 data, suggested that three dominant genes (PS3, PS2 and PS1) controlled the expression of photo-sensitivity. These genes were found operating in a hierarchical order with PS2 and PS1 genes failing to express in the presence of PS3 gene. Similarly in the absence of PS3 gene, PS2 expressed but it masked the expression of PS1. Further, PS1 gene expressed only when both PS3 and PS2 were in recessive homozygous state. Hence, the proposed genetic model for photosensitivity in pigeonpea is PS3 > PS2 > PS1 and photoinsensitive genotype being a triple recessive (ps3ps3ps2 ps2ps1ps1)

Sorghum and Millets Commodity and Research Environments

Sorghum and millets are strategic commodities for worldwide food security, particularly in the harsh environments of the semi-arid tropics. This volume outlines the production and research environment of these crops in each major region, and seeks to provide a guide to the research required to achieve sustained improvements in production