Macroscopic quantum computation using Bose-Einstein condensates

Quantum computation using qubits made of two component Bose-Einstein condensates (BECs) is analysed. The use of BECs allows for an increase of energy scales via bosonic enhancement, resulting in gate operations that can be performed at a macroscopically large energy scale. The large energy scale of the gate operations results in quantum algorithms that may be executed at a time reduced by a factor of N, where N is the number of bosons per qubit. The encoding of the qubits allows for no intrinsic penalty on decoherence times. We illustrate the scheme by an application to Deutsch's and Grover's algorithms.Comment: 10 pages, 3 figure

Quantum simulation of Fermi-Hubbard models in semiconductor quantum dot arrays

We propose a device for studying the Fermi-Hubbard model with long-range Coulomb interactions using an array of quantum dots defined in a semiconductor two-dimensional electron gas system. Bands with energies above the lowest energy band are used to form the Hubbard model, which allows for an experimentally simpler realization of the device. We find that depending on average electron density, the system is well described by a one- or two-band Hubbard model. Our device design enables the control of the ratio of the Coulomb interaction to the kinetic energy of the electrons independently to the filling of the quantum dots, such that a large portion of the Hubbard phase diagram may be probed. Estimates of the Hubbard parameters suggest that a metal-Mott insulator quantum phase transition and a d-wave superconducting phase should be observable using current fabrication technologies.Comment: 12 pages, 3 figures, 1 table

Inhomogeneous non-Gaussianity

We propose a method to probe higher-order correlators of the primordial density field through the inhomogeneity of local non-Gaussian parameters, such as f_NL, measured within smaller patches of the sky. Correlators between n-point functions measured in one patch of the sky and k-point functions measured in another patch depend upon the (n+k)-point functions over the entire sky. The inhomogeneity of non-Gaussian parameters may be a feasible way to detect or constrain higher-order correlators in local models of non-Gaussianity, as well as to distinguish between single and multiple-source scenarios for generating the primordial density perturbation, and more generally to probe the details of inflationary physics.Comment: 16 pages, 2 figures; v2: Minor changes and references added. Matches the published versio

Identifying Novel Triggers of the Intracellular Pathogen Response (IPR) in C. elegans

The intracellular pathogen response (IPR) is a cell signaling pathway found in C. elegans that is triggered when pathogenic microorganisms invade, and immune responses attempt to eliminate the threat. Due to the relative simplicity of C. elegans, they are an excellent model organism to analyze the cell signaling pathways triggered by various pathogens. They lack the complex immune systems of larger organisms, making it easier to study the involved cell signaling pathways. Past studies have shown that the IPR can also be triggered via intestinal wounding. Heat stress, viral infection, and proteasome stress are all known triggers of the IPR. The long-term goal of this project is to generate potential new triggers, the response of which will be compared to the response generated by known triggers. The IPR will be quantified by measuring nanoluciferase expression, which is driven by an IPR gene. The immediate goal of this project is to develop this nanoluciferase assay system to generate IPR activity data in a high-throughput fashion. We hope to eventually be able to relate our findings to similar pathways in humans and other vertebrates. While humans do not have the IPR that is found in C. elegans, they have similar pathways that perform equivalent functions. In particular, we are interested in how intestinal damage could be related to activation of innate immunity. This information could be used to gain a better understanding of gastrointestinal diseases, specifically inflammatory bowel diseases

Primordial black holes as a tool for constraining non-Gaussianity

Primordial Black Holes (PBH's) can form in the early Universe from the collapse of large density fluctuations. Tight observational limits on their abundance constrain the amplitude of the primordial fluctuations on very small scales which can not otherwise be constrained, with PBH's only forming from the extremely rare large fluctuations. The number of PBH's formed is therefore sensitive to small changes in the shape of the tail of the fluctuation distribution, which itself depends on the amount of non-Gaussianity present. We study, for the first time, how quadratic and cubic local non-Gaussianity of arbitrary size (parameterised by f_nl and g_nl respectively) affects the PBH abundance and the resulting constraints on the amplitude of the fluctuations on very small scales. Intriguingly we find that even non-linearity parameters of order unity have a significant impact on the PBH abundance. The sign of the non-Gaussianity is particularly important, with the constraint on the allowed fluctuation amplitude tightening by an order of magnitude as f_nl changes from just -0.5 to 0.5. We find that if PBH's are observed in the future, then regardless of the amplitude of the fluctuations, non-negligible negative f_nl would be ruled out. Finally we show that g_nl can have an even larger effect on the number of PBH's formed than f_nl.Comment: 9 pages, 5 figures, v2: version to appear in Phys. Rev. D with minor changes, v3: typos corrected (including factor of 1/2 in erfc prefactor), no changes to result

Scale-dependent non-Gaussianity probes inflationary physics

We calculate the scale dependence of the bispectrum and trispectrum in (quasi) local models of non-Gaussian primordial density perturbations, and characterize this scale dependence in terms of new observable parameters. They can help to discriminate between models of inflation, since they are sensitive to properties of the inflationary physics that are not probed by the standard observables. We find consistency relations between these parameters in certain classes of models. We apply our results to a scenario of modulated reheating, showing that the scale dependence of non-Gaussianity can be significant. We also discuss the scale dependence of the bispectrum and trispectrum, in cases where one varies the shape as well as the overall scale of the figure under consideration. We conclude providing a formulation of the curvature perturbation in real space, which generalises the standard local form by dropping the assumption that f_NL and g_NL are constants.Comment: 27 pages, 2 figures. v2: Minor changes to match the published versio