Polarization of Cosmic Microwave Background

In this work we present an extension of the ROMA map-making code for data analysis of Cosmic Microwave Background polarization, with particular attention given to the inflationary polarization B-modes. The new algorithm takes into account a possible cross-correlated noise component among the different detectors of a CMB experiment. We tested the code on the observational data of the BOOMERanG (2003) experiment and we show that we are provided with a better estimate of the power spectra, in particular the error bars of the BB spectrum are smaller up to 20% for low multipoles. We point out the general validity of the new method. A possible future application is the LSPE balloon experiment, devoted to the observation of polarization at large angular scales.Comment: 6 pages, 4 figures, proceedings of the 6th Young Researchers Meeting, L'Aquila, Oct 12th-14th 201

Optimal strategy for polarization modulation in the LSPE-SWIPE experiment

CMB B-mode experiments are required to control systematic effects with an unprecedented level of accuracy. Polarization modulation by a half wave plate (HWP) is a powerful technique able to mitigate a large number of the instrumental systematics. Our goal is to optimize the polarization modulation strategy of the upcoming LSPE-SWIPE balloon-borne experiment, devoted to the accurate measurement of CMB polarization at large angular scales. We depart from the nominal LSPE-SWIPE modulation strategy (HWP stepped every 60 s with a telescope scanning at around 12 deg/s) and perform a thorough investigation of a wide range of possible HWP schemes (either in stepped or continuously spinning mode and at different azimuth telescope scan-speeds) in the frequency, map and angular power spectrum domain. In addition, we probe the effect of high-pass and band-pass filters of the data stream and explore the HWP response in the minimal case of one detector for one operation day (critical for the single-detector calibration process). We finally test the modulation performance against typical HWP-induced systematics. Our analysis shows that some stepped HWP schemes, either slowly rotating or combined with slow telescope modulations, represent poor choices. Moreover, our results point out that the nominal configuration may not be the most convenient choice. While a large class of spinning designs provides comparable results in terms of pixel angle coverage, map-making residuals and BB power spectrum standard deviations with respect to the nominal strategy, we find that some specific configurations (e.g., a rapidly spinning HWP with a slow gondola modulation) allow a more efficient polarization recovery in more general real-case situations. Although our simulations are specific to the LSPE-SWIPE mission, the general outcomes of our analysis can be easily generalized to other CMB polarization experiments.Comment: 11 pages, 9 figures, accepted for publication in A&

Optimization of the half wave plate configuration for the LSPE-SWIPE experiment

The search for the B-mode polarization of Cosmic Microwave Background (CMB) is the new frontier of observational Cosmology. A B-mode detection would give an ultimate confirmation to the existence of a primordial Gravitational Wave (GW) background as predicted in the inflationary scenario. Several experiments have been designed or planned to observe B-modes. In this work we focus on the forthcoming Large Scale Polarization Explorer (LSPE) experiment, that will be devoted to the accurate measurement of CMB polarization at large angular scales. LSPE consists of a balloon-borne bolometric instrument, the Short Wavelength Instrument for the Polarization Explorer (SWIPE), and a ground-based coherent polarimeter array, the STRatospheric Italian Polarimeter (STRIP). SWIPE will employ a rotating Half Wave Plate (HWP) polarization modulator to mitigate the systematic effects due to instrumental non-idealities. We present here preliminary forecasts aimed at optimizing the HWP configuration.Comment: 6 pages, 4 figures, proceedings of the 7th Young Researcher Meeting, Torino, Oct 24th-26th 201

Optimal strategy for polarization modulation in the LSPE-SWIPE experiment

Context. Cosmic microwave background (CMB) B-mode experiments are required to control systematic effects with an unprecedented level of accuracy. Polarization modulation by a half wave plate (HWP) is a powerful technique able to mitigate a large number of the instrumental systematics. Aims. Our goal is to optimize the polarization modulation strategy of the upcoming LSPE-SWIPE balloon-borne experiment, devoted to the accurate measurement of CMB polarization at large angular scales. Methods. We departed from the nominal LSPE-SWIPE modulation strategy (HWP stepped every 60 s with a telescope scanning at around 12 deg/s) and performed a thorough investigation of a wide range of possible HWP schemes (either in stepped or continuously spinning mode and at different azimuth telescope scan-speeds) in the frequency, map and angular power spectrum domain. In addition, we probed the effect of high-pass and band-pass filters of the data stream and explored the HWP response in the minimal case of one detector for one operation day (critical for the single-detector calibration process). We finally tested the modulation performance against typical HWP-induced systematics. Results. Our analysis shows that some stepped HWP schemes, either slowly rotating or combined with slow telescope modulations, represent poor choices. Moreover, our results point out that the nominal configuration may not be the most convenient choice. While a large class of spinning designs provides comparable results in terms of pixel angle coverage, map-making residuals and BB power spectrum standard deviations with respect to the nominal strategy, we find that some specific configurations (e.g., a rapidly spinning HWP with a slow gondola modulation) allow a more efficient polarization recovery in more general real-case situations. Conclusions. Although our simulations are specific to the LSPE-SWIPE mission, the general outcomes of our analysis can be easily generalized to other CMB polarization experiments

Class structure and technological replaceability of the European workforce.

In this excerpt of my Master’s thesis, I describe the class structure and the degree of technological replaceability of the workforce in thirteen European countries. This investigation allows me to test the “routine-biased technical change” framework, which states that middle-class workers are the most exposed to the automation risk (Autor et al., 2003). The class analysis is based on the occupational scheme elaborated by Daniel Oesch (2006), and the countries are clustered into four welfare regimes (Esping-Andersen, 1990). I also plot a longitudinal analysis describing the evolution of the class structure since the early 2000s. Some relevant differences emerge among regimes. Conservative and Mediterranean countries appear committed to preserving the clerical and industrial workforce, whereas Liberal countries are characterized by large groups of entrepreneurial and low-skill service occupations. The Social Democratic regime shows a great effort in upskilling workers without altering the service transition. As regards technological replaceability, education seems to matter more than what is stated by the RBTC scholars. More specifically, low-skill occupations – especially in the interpersonal service sector – appear more replaceable than expected. Hence, the middle class can be split into two groups based on educational attainment, and the least skilled branch turns out to be more replaceable than the most educated. Finally, automation affects national workforces differently: the Nordic and Anglo-Saxon labor forces appear more resilient than the Continental and Mediterranean ones

Interleukin-17A promotes parietal cell atrophy by inducing apoptosis

Background & Aims: Atrophic gastritis caused by chronic inflammation in the gastric mucosa leads to the loss of gastric glandular cells, including acid-secreting parietal cells. Parietal cell atrophy in a setting of chronic inflammation induces spasmolytic polypeptide expressing metaplasia, a critical step in gastric carcinogenesis. However, the mechanisms by which inflammation causes parietal cell atrophy and spasmolytic polypeptide expressing metaplasia are not well defined. We investigated the role of interleukin-17A (IL-17A) in causing parietal cell atrophy. Methods: A mouse model of autoimmune atrophic gastritis was used to examine IL-17A production during early and late stages of disease. Organoids derived from corpus glands were used to determine the direct effects of IL-17A on gastric epithelial cells. Immunofluorescent staining was used to examine IL-17A receptors and the direct effect of signaling on parietal cells. Mice were infected with an IL-17A-producing adenovirus to determine the effects of IL-17A on parietal cells in vivo. Finally, IL-17A neutralizing antibodies were administered to mice with active atrophic gastritis to evaluate the effects on parietal cell atrophy and metaplasia. Results: Increased IL-17A correlated with disease severity in mice with chronic atrophic gastritis. IL-17A caused caspase-dependent gastric organoid degeneration, which could not be rescued with a necroptosis inhibitor. Parietal cells expressed IL-17A receptors and IL-17A treatment induced apoptosis in parietal cells. Overexpressing IL-17A in vivo induced caspase-3 activation and terminal deoxynucleotidyl transferase–mediated deoxyuridine triphosphate nick-end labeling staining in parietal cells. Finally, IL-17A neutralizing antibody decreased parietal cell atrophy and metaplasia in mice with chronic atrophic gastritis. Conclusions: These data identify IL-17A as a cytokine that promotes parietal cell apoptosis during atrophic gastritis, a precursor lesion for gastric cancer. Keywords: IL-17A, Atrophy, Metaplasia, Apoptosi

Islands in the Stream: Style and Experience in Hemingway

Master of Arts (MA