910 research outputs found

    Wavelet reconstruction of E and B modes for CMB polarisation and cosmic shear analyses

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    We present new methods for mapping the curl-free (E-mode) and divergence-free (B-mode) components of spin 2 signals using spin directional wavelets. Our methods are equally applicable to measurements of the polarisation of the cosmic microwave background (CMB) and the shear of galaxy shapes due to weak gravitational lensing. We derive pseudo and pure wavelet estimators, where E-B mixing arising due to incomplete sky coverage is suppressed in wavelet space using scale- and orientation-dependent masking and weighting schemes. In the case of the pure estimator, ambiguous modes (which have vanishing curl and divergence simultaneously on the incomplete sky) are also cancelled. On simulations, we demonstrate the improvement (i.e., reduction in leakage) provided by our wavelet space estimators over standard harmonic space approaches. Our new methods can be directly interfaced in a coherent and computationally-efficient manner with component separation or feature extraction techniques that also exploit wavelets

    Translational control of the SigR-directed oxidative stress response in streptomyces via IF3-mediated repression of a noncanonical GTC start codon

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    The major oxidative stress response in Streptomyces is controlled by the sigma factor SigR and its cognate antisigma factor RsrA, and SigR activity is tightly controlled through multiple mechanisms at both the transcriptional and posttranslational levels. Here we show that sigR has a highly unusual GTC start codon and that this leads to another level of SigR regulation, in which SigR translation is repressed by translation initiation factor 3 (IF3). Changing the GTC to a canonical start codon causes SigR to be overproduced relative to RsrA, resulting in unregulated and constitutive expression of the SigR regulon. Similarly, introducing IF3* mutations that impair its ability to repress SigR translation has the same effect. Thus, the noncanonical GTC sigR start codon and its repression by IF3 are critical for the correct and proper functioning of the oxidative stress regulatory system. sigR and rsrA are cotranscribed and translationally coupled, and it had therefore been assumed that SigR and RsrA are produced in stoichiometric amounts. Here we show that RsrA can be transcribed and translated independently of SigR, present evidence that RsrA is normally produced in excess of SigR, and describe the factors that determine SigR-RsrA stoichiometry.IMPORTANCE In all sigma factor-antisigma factor regulatory switches, the relative abundance of the two proteins is critical to the proper functioning of the system. Many sigma-antisigma operons are cotranscribed and translationally coupled, leading to a generic assumption that the sigma and antisigma factors are produced in a fixed 1:1 ratio. In the case of sigR-rsrA, we show instead that the antisigma factor is produced in excess over the sigma factor, providing a buffer to prevent spurious release of sigma activity. This excess arises in part because sigR has an extremely rare noncanonical GTC start codon, and as a result, SigR translation initiation is repressed by IF3. This finding highlights the potential significance of noncanonical start codons, very few of which have been characterized experimentally. It also emphasizes the limitations of predicting start codons using bioinformatic approaches, which rely heavily on the assumption that ATG, GTG, and TTG are the only permissible start codons

    Controlling magnetic anisotropy in La<sub>0.7</sub>Sr<sub>0.3</sub>MnO<sub>3</sub> nanostructures

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    We have developed a chlorine based dry etching process for nanopatterning the ferromagnetic oxide La&lt;sub&gt;0.7&lt;/sub&gt;Sr&lt;sub&gt;0.3&lt;/sub&gt;MnO&lt;sub&gt;3&lt;/sub&gt; (LSMO). Large arrays of millions of identical structures have been fabricated from thin LSMO films by electron-beam lithography and reactive ion etching. SQUID magnetometry demonstrates that patterned nanostructures with lateral dimensions down to 100 nm retain their full magnetization and the Curie temperature of the bulk layer. In addition, their shape anisotropy is sufficient to overcome the crystalline anisotropy of the bulk. High resolution scanning transmission electron microscopy shows that crystallinity is preserved even at the edges of the nanostructures

    The Impact of Diversity Promise Fulfillment on Professionals of Color Outcomes in the USA

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    This paper explores the relationship between psychological contract violations (PCVs) related to diversity climate and professional employee outcomes. We found that for our sample of US professionals of color including US-born African Americans, Hispanics, Asians, and Native Americans, employee perceptions of breach in diversity promise fulfillment (DPF), after controlling for more general organizational promise fulfillment (OPF), led to lower reported organizational commitment (OC) and higher turnover intentions (TI). Interactional justice partially mediated the relationship between DPF and outcomes. Procedural justice and DPF interacted to influence OC of employees of color. For respondents who perceived a lack of DPF, moderate racial awareness was associated with greater PCV. We discuss the implications of the findings and provide directions for future research

    Diversity climate impact on employee of color outcomes: does justice matter?

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    Purpose – The purposes of this paper are three-fold: first, to examine the effect of diversity climate on professional employee of color outcomes, organizational commitment and turnover intentions; second, to investigate the moderating and mediating roles of interactional and procedural justice on the relationships between diversity climate and the outcomes; and third, to explore the interactive effect of racial awareness and diversity climate on reported psychological contract violation. Design/methodology/approach – The authors conducted a survey of 182 professionals of color. Correlation, factor analysis, and regression were employed to test the hypotheses. Findings – Results indicate that diversity climate affects organizational commitment and turnover intentions. Interactional and procedural justice played mediating roles between diversity climate and employee outcomes. Moderated mediation analysis indicated that for turnover intentions, there was moderated mediation under both low and high procedural justice conditions. When a diversity climate was perceived to be fair, racially aware respondents reported lower levels of psychological contract violation. Research limitations/implications – Professionals of color from one US industry completed the survey, so conclusions about generalizability should be drawn with caution. Data were cross-sectional and single-source. However, the findings were consistent with past research, lending credibility to the results. Originality/value – Recent research on workforce diversity has highlighted the importance of effectively managing all organizational members. The paper shows that the diversity climate and organizational justice impact employee of color outcomes. Thus, for managers, creating and maintaining a positive, fair diversity climate will be important for attracting and retaining high-quality professionals of color in US organizations

    The challenge of increasing minority-group professional representation in the United States: intriguing findings

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    Census statistics highlight the increasing diversity of the populace in the United States. However, minority-group Americans continue to be under-represented in professional occupations. Six propositions for low minority-group professional presence in US organizations are that under-representation is due to leader racial insensitivity, discrimination, the (small) pipeline of minority-group professional employees, (un)equal opportunity theory, rational person economic theory, and low organizational diversity strategic priority. We describe and explore these six arguments with related empirical tests. Results indicated that leader-rated importance of cultural change, above and beyond leader racial awareness, influenced representation. The more specific strategies of diversity recruitment and provision of performance feedback also predicted minority-group representation, while diversity as an organizational strategic priority did not. We discuss the implications of these findings and present directions for future research

    An empirical test of diversity climate dimensionality and relative effects on employee of color outcomes.

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    This study examined the relative effect of diversity climate dimensions captured by two measures: Mor Barak et al.’s (Journal of Applied Behavioral Science, 34:82–104, 1998) diversity climate scale and Chrobot-Mason’s (Journal of Managerial Psychology 18:22–45, 2003) diversity promise fulfillment scale on professional employee of color outcomes: organizational commitment (OC) and turnover intentions. We hypothesized that the two scales would measure different aspects of diversity climate. We further hypothesized that the different climate dimensions would interactively affect the employee of color outcomes. Third, we predicted that diversity climate would mediate between diversity promise fulfillment and employee of color outcomes. Finally, we hypothesized that organizational commitment would mediate the interactive effect of diversity climate dimensions on turnover intentions. Results indicated that the diversity scales each predicted unique variance in employee outcomes and that the climate dimensions interactively influenced professional of color organizational commitment and turnover intentions. We also found that the diversity climate dimension, as measured by the Mor Barak scale, mediated between diversity promise fulfillment and the outcomes. Finally, we found complete mediated moderation between the interaction of the two climate measures and turnover intentions by organizational commitment. Implications are discussed

    Conduit flow experiments help constraining the regime of explosive eruptions

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    It is currently impractical to measure what happens in a volcano during an explosive eruption, and up to now much of our knowledge depends on theoretical models. Here we show, by means of large‐scale experiments, that the regime of explosive events can be constrained on the basis of the characteristics of magma at the point of fragmentation and conduit geometry. Our model, whose results are consistent with the literature, is a simple tool for defining the conditions at conduit exit that control the most hazardous volcanic regimes. Besides the well‐known convective plume regime, which generates pyroclastic fallout, and the vertically collapsing column regime, which leads to pyroclastic flows, we introduce an additional regime of radially expanding columns, which form when the eruptive gas‐particle mixture exits from the vent at overpressure with respect to atmosphere. As a consequence of the radial expansion, a dilute collapse occurs, which favors the formation of density currents resembling natural base surges. We conclude that a quantitative knowledge of magma fragmentation, i.e., particle size, fragmentation energy, and fragmentation speed, is critical for determining the eruption regime.Research was partially funded by DPC-INGV agreement 07‐09 and MUR PRIN 06.PublishedB042043.6. Fisica del vulcanismoJCR Journalrestricte

    Onboard Hydrogen/Helium Sensors in Support of the Global Technical Regulation: An Assessment of Performance in Fuel Cell Electric Vehicle Crash Tests

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    Automobile manufacturers in North America, Europe, and Asia project a 2015 release of commercial hydrogen fuel cell powered light-duty road vehicles. These vehicles will be for general consumer applications, albeit initially in select markets but with much broader market penetration expected by 2025. To assure international harmony, North American, European, and Asian regulatory representatives are striving to base respective national regulations on an international safety standard, the Global Technical Regulation (GTR), Hydrogen Fueled Vehicle, which is part of an international agreement pertaining to wheeled vehicles and equipment for wheeled vehicles

    Conduit flow experiments help constraining the regime of explosive eruptions

    Get PDF
    It is currently impractical to measure what happens in a volcano during an explosive eruption, and up to now much of our knowledge depends on theoretical models. Here we show, by means of large‐scale experiments, that the regime of explosive events can be constrained on the basis of the characteristics of magma at the point of fragmentation and conduit geometry. Our model, whose results are consistent with the literature, is a simple tool for defining the conditions at conduit exit that control the most hazardous volcanic regimes. Besides the well‐known convective plume regime, which generates pyroclastic fallout, and the vertically collapsing column regime, which leads to pyroclastic flows, we introduce an additional regime of radially expanding columns, which form when the eruptive gas‐particle mixture exits from the vent at overpressure with respect to atmosphere. As a consequence of the radial expansion, a dilute collapse occurs, which favors the formation of density currents resembling natural base surges. We conclude that a quantitative knowledge of magma fragmentation, i.e., particle size, fragmentation energy, and fragmentation speed, is critical for determining the eruption regime
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