7,190 research outputs found

    Fair Use Challenges in Academic and Research Libraries

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    Summarizes findings from a survey of librarians on the application of fair use in copyright practice to fulfill libraries' missions of teaching and learning support, scholarship support preservation, exhibition, and public outreach

    Virtual fences for controlling cows

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    We describe a moving virtual fence algorithm for herding cows. Each animal in the herd is given a smart collar consisting of a GPS, PDA, wireless networking and a sound amplifier. Using the GPS, the animal's location can be verified relative to the fence boundary. When approaching the perimeter, the animal is presented with a sound stimulus whose effect is to move away. We have developed the virtual fence control algorithm for moving a herd. We present simulation results and data from experiments with 8 cows equipped with smart collars

    Health Benefits for the Uninsured: Design and Early Implementation of the Accelerated Benefits Demonstration

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    Many Social Security Disability Insurance (SSDI) beneficiaries have serious and immediate health care needs, but, under current law, most are not eligible for Medicare until 24 months after they start receiving cash benefits. This policy brief describes a new project that is testing whether providing earlier access to health benefits, as well as other services, for new SSDI beneficiaries who have no other health insurance improves employment and health outcomes

    Marked expansion of exocrine and endocrine pancreas with incretin therapy in humans with increased exocrine pancreas dysplasia and the potential for glucagon-producing neuroendocrine tumors.

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    Controversy exists regarding the potential regenerative influences of incretin therapy on pancreatic ÎČ-cells versus possible adverse pancreatic proliferative effects. Examination of pancreata from age-matched organ donors with type 2 diabetes mellitus (DM) treated by incretin therapy (n = 8) or other therapy (n = 12) and nondiabetic control subjects (n = 14) reveals an ∌40% increased pancreatic mass in DM treated with incretin therapy, with both increased exocrine cell proliferation (P < 0.0001) and dysplasia (increased pancreatic intraepithelial neoplasia, P < 0.01). Pancreata in DM treated with incretin therapy were notable for α-cell hyperplasia and glucagon-expressing microadenomas (3 of 8) and a neuroendocrine tumor. ÎČ-Cell mass was reduced by ∌60% in those with DM, yet a sixfold increase was observed in incretin-treated subjects, although DM persisted. Endocrine cells costaining for insulin and glucagon were increased in DM compared with non-DM control subjects (P < 0.05) and markedly further increased by incretin therapy (P < 0.05). In conclusion, incretin therapy in humans resulted in a marked expansion of the exocrine and endocrine pancreatic compartments, the former being accompanied by increased proliferation and dysplasia and the latter by α-cell hyperplasia with the potential for evolution into neuroendocrine tumors

    Letter to Children from Peter and Rachel Butler

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    Peter and Rachel Butler describe family health and well being, the discovery of a gold mine along the Columbia River, and financial and business matters

    Non-LTE line-formation for CNO

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    Accurate atomic data have become available in the recent past due to the demands of astrophysics and fusion research. We report on the impact of such data on non-LTE line-formation calculations for CNO in early-type stars. Considerable improvement is achieved by the derivation of consistent results from practically all available spectroscopic indicators, regardless of ionization stage or spin system, and the uncertainties in the analyses are drastically reduced. Moreover, systematic trends are revealed, e.g. an increase of the NI abundances from previous studies of BA-type supergiants by a factor of two is indicated. The present work promises stringent observational constraints on chemical mixing in the course of massive star evolution. First results on BA-type supergiants in the Galaxy and the Magellanic Clouds are discussed.Comment: 6 pages, 2 figures; to be published in "CNO in the Universe", ASP Conf. Series, eds. C. Charbonnel, D. Schaerer & G. Meyne

    Mihai Gheorghiade, MD-Life and Concepts

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    How do you capture an idea, shape it, and then bring it into the world? Of his many talents, this ability was a fundamental characteristic of Mihai Gheorghiade. A quick glance through PubMed confirms his prodigious output, likely to overwhelm any novice or even expert scholar. His contribution to heart failure, especially acute heart failure (AHF), is profound, He authored several major concepts in acute heart failure, disseminated further by his students. Most concepts remained indelibly linked to his name: Digoxin trials research(1–3), AHFS (acute heart failure syndromes) definition(4), hemodynamic congestion(5), hospitalized heart failure (HHF) (6), the vulnerable phase(7,8), neutral hemodynamic agents(9), registries(10–12) and pre-trial registries(13), the “6-axis model”(14) and then the “8-axis model”(15). His work shaped the field of AHF
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