14 research outputs found

    Role of cardiac MRI in detecting familial hypertrophic cardiomyopathy : Review / Marymol Koshy โ€ฆ [et al.]

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    Hypertrophic cardiomyopathy (HCM) is a global disease affecting people of various ethnic origins and both genders. HCM is a genetic disorder with a wide range of symptoms, including the catastrophic presentation of sudden cardiac death. Proper diagnosis and treatment of this disorder can relieve symptoms and prolong life. Non-invasive imaging is essential in diagnosing HCM. We present a review to deliberate the potential use of cardiac magnetic resonance (CMR) imaging in HCM assessment and also identify the risk factors entailed with risk stratification of HCM based on Magnetic Resonance Imaging (MRI). KEYWORDS: Hypertrophic cardiomyopathy (HCM), Magnetic Resonance Imaging (MRI), Sudden Cardiac Death (SCD), Late gadolinium enhancement (LGE), Phenotypes, Left ventricular hypertrophy (LVH), Left ventricular outflow obstruction (LVOT), Risk Stratification

    Abstracts from the 3rd International Genomic Medicine Conference (3rd IGMC 2015)

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    Unilateral Nonconfluent Cluster of Micronodules: Atypical Radiologic Appearance of Pulmonary Tuberculosis in an Immunocompetent Patient

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    Active pulmonary tuberculosis involving the lung parenchyma is typically seen on CT as consolidation, centrilobular nodules with tree-in-bud branching, cavitating lesions, and miliary nodules. However, some atypical CT patterns of granulomatous disease including tuberculosis have been recently described, namely, clusters of nodules without confluence or with confluence. We present a case of a patient who was found to have nonconfluent clusters of micronodules in the right lung with negative sputum culture for tuberculosis. There were also incidental findings of the partial duplex system of the left kidney with mild-to-moderate hydronephrosis in the lower moiety with proximal hydroureter. The urine culture was then positive for mycobacterium tuberculosis; hence, he was commenced on antituberculous medications. A repeated CT scan revealed significant improvement of the aforementioned clusters of micronodules and left hydronephrosis. In the present case, we would like to highlight the atypical appearances of pulmonary tuberculosis in the form of nonconfluent micronodules on HRCT despite negative sputum workup, with the concurrent active genitourinary tuberculosis

    Pilot study on the effect of Yasiin recitation on the haemodynamics of ventilated patients

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    Introduction: Qurโ€™anic verses recitations to ill patients are practiced by many Muslims as a form of healing and worship. The effectiveness has been observed in many medical institutions; however, it has never been objectively measured and documented. This pilot study was conducted to construct a methodological approach to evaluate the therapeutic effects of Yasiin recitation on the haemodynamics of critically ill patients. Methods: Ventilated Muslim patients in coronary care unit of a teaching hospital were evaluated. Yasiin was recited twice; by one of the researchers and then by the patientsโ€™ relatives. Mean arterial blood pressure, pulse rate, oxygen saturation level and electrocardiographic changes, were observed. The difference of the parameters before and during recitation was analysed. Results: Five patients fulfilling the selection criteria were selected; two acute myocardial infarctions, two congestive cardiac failures, and a third-degree atrioventricular block. Based on a non-parametric two-related-sample test, the haemodynamic parameters were not significantly affected by Yaasiin recitation. At the end of the study, two of the patients passed away, one patient was extubated and survived. Two patients were still on ventilators when the study had been completed. Limitations in the study were observed and highlighted in explaining the equivocal results. Conclusions: The effect of Yasiin recitation on heamodynamics of patients was not proven in this study. Further refinements might be needed based upon the observation on limitations encountered. It is hoped that this humble effort would pave the way for further studies to explore this field

    Unilateral pulmonary artery agenesis: An unusual cause of hemoptysis

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    Introduction: Unilateral pulmonary artery agenesis (UPAA) is a rare congenital malformation of the pulmonary artery due to agenesis of the sixth aortic arch during embryogenesis. Diagnosis can be challenging due to variable clinical presentations. Case: A 29-year-old female at third trimester of twin pregnancy presented with massive hemoptysis. Computed tomography angiogram (CTA) showed unilateral absence of the right pulmonary artery with multiple dilated tortuous bronchial arteries supplying the right lung. Selective embolization of the bronchial artery was performed post-partum. Conclusion: Clinicians should have a high clinical suspicion of collateral artery bleeding in patients who present with unexplained hemoptysis and typical UPAA radiographic findings

    Knowledge, attitude and practice on hygiene of Kampung Sungai Karang Darat residents and its related factors November 2003

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    Introduction: A cross-sectional study was conducted in September 2003 to evaluate the Knowledge, Attitude and Practice (KAP) level on hygiene of Kampung Sungai Karang Darat residents and its related factors. Methodology: It was a cross-sectional study conducted by a group of year four medical students 2003/2004 from Community Health and Family Medicine posting, Kulliyyah of Medicine, IIUM. Data collection methods included observations and interview-guided questionnaires. Out of the total number of 2620 residents, 304 people aged 18 and above from 200 houses which were randomly selected from 600 houses in that village were surveyed on the KAP of hygiene. We then determined the factors that affect the KAP level, and how it in turn influenced the health status of the respondents, particularly their susceptibility towards hygiene-related diseases. Result: From the statistical analysis, it was found that the mean KAP score of the respondents was 26.42+4.15, on a scale that ranged from 0 to 39 with the lowest KAP score of 14 and the highest KAP score of 36. It was then found that the higher the age of the respondents, the lower the KAP score (p<0.001). Higher socioeconomic status was associated with higher KAP score (occupation (p=0.007), academic level (p<0.001), and income per capita (p<0.001)). Malaysians of non-Pahang origin also had higher KAP score compared to residents of Pahang origin (p<0.001). People living in modern houses had a higher KAP value than those living in traditional houses (p<0.001). Housing quality also had effect on the KAP score (r=+0.665). However, the KAP level was not significantly related to gender difference (p=0.162). Personal hygiene had the lowest mean KAP score, followed by domestic hygiene and then community hygiene. Meanwhile, the highest mean low KAP score were found to have no significant preponderance towards hygiene-related diseases (p=0.409) Conclusion: Overall, the KAP level on hygiene of residents of Kampung Sungai Karang Darat was at a satisfactory level
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