326 research outputs found

    Letter from J. Tolbert Bushong to B. R. Colson

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    Letter from J. Tolbert Bushong to B. R. Colson. The one-page handwritten note is dated 12 August 1912. A transcription of the letter is included in the item PDF

    Letter from J. Tolbert Bushong to B. R. Colsum [sic]

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    Letter from J. Tolbert Bushong to B. R. Colsum [sic]. The one-page typewritten letter to B. R. Colson is on South Florida Seminary letterhead and is dated 21 October 1912

    Letter from J. T. Bushong to B. R. Colson

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    Letter from J. T. Bushong to B. R. Colson. The three-page handwritten letter is dated 30 April 1910. There is a transcript of the correspondence in the item PDF

    Letter from J. T. Bushong to B. R. Colson

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    Letter from J. T. Bushong to B. R. Colson. The one-page handwritten note is dated 16 July 1908

    Tomographic measurements of barotropic motions

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    Submitted in partial fulfillment of the requirements for the degree of Ocean Engineer at the Massachusetts Institute of Technology and the Woods Hole Oceanographic Institution August 1987In 1983, continuous acoustic transmissions centered at 133 Hz and with a resolution of 60 ms were transmitted for five days from Oahu to the coast of Northern California (4000 km range). A maximum likelihood estimate of the change in acoustic travel time (based on phase) between received pulses is used to estimate barotropic fluctilations. Analysis of the resulting time series reveals resonant oscillations at nontidal frequencies in the Northeast Pacific. Some of the periods of the resonant oscillations are consistent with theory (Platzman, Curtis, Hansen, and Slater, 1981). A Wiener filter is formulated for estimating the barotropic tides from a basin scale tomographic array. Error analyses indicate an ability to estimate barotropic currents and surface displacements with errors less than 0.01 cm/s and 1 cm, respectively, over a large portion of the Northeast Pacific

    Letter to B. R. Colson with attached portion of letter to J. T. Bushong from N. A. Jones

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    Letter to B. R. Colson with attached portion of letter to J. T. Bushong from N. A. Jones. The letter to B. R. Colson from J. T. Bushong is dated 20 January 1909. There is a transcript of the letters in the item PDF

    Letter from John E. King and J. Tolbert Bushong to Brother Larimore

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    Letter from J. Tolbert Bushong and John E. King on South Florida Seminary letterhead and John E. King stationery to Theophilus Brown Larimore. The correspondence is handwritten and three pages long. The letter is dated 1912 February 22. There is a transcript of the correspondence in the item PDF

    An Approach to Reducing Accounting Costs for Small Businesses

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    Many small privately-held businesses (referred to as small businesses henceforth) prepare financial statements for use by external parties such as banks. Often the small businesses do not have the expertise to prepare these financial statements, instead employing independent certified public accountants (CPAs) for the task. A CPA preparing financial statements in this manner must attach a report stating the degree of responsibility he/she is accepting /or the statements.  Modification of this report results if the statements are not in conformance with generally accepted accounting principles (GAAP). Owners of small businesses generally elect to have their financial statements produced following GAAP to avoid the modification of the report.  This has become a costly decision, however, as the complexity of GAAP has increased the purpose of this article is to help small business owners reduce the cost of preparing their financial statements. The article begins with a discussion of the importance of selecting the right CPA to produce the financial statements. The article then reviews the CPA's level of association with financial statements and the reports that result therefrom. Finally, the article closes with possible reduction of accounting costs through the use of other bases of accounting

    A workflow for the automatic segmentation of organelles in electron microscopy image stacks.

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    Electron microscopy (EM) facilitates analysis of the form, distribution, and functional status of key organelle systems in various pathological processes, including those associated with neurodegenerative disease. Such EM data often provide important new insights into the underlying disease mechanisms. The development of more accurate and efficient methods to quantify changes in subcellular microanatomy has already proven key to understanding the pathogenesis of Parkinson's and Alzheimer's diseases, as well as glaucoma. While our ability to acquire large volumes of 3D EM data is progressing rapidly, more advanced analysis tools are needed to assist in measuring precise three-dimensional morphologies of organelles within data sets that can include hundreds to thousands of whole cells. Although new imaging instrument throughputs can exceed teravoxels of data per day, image segmentation and analysis remain significant bottlenecks to achieving quantitative descriptions of whole cell structural organellomes. Here, we present a novel method for the automatic segmentation of organelles in 3D EM image stacks. Segmentations are generated using only 2D image information, making the method suitable for anisotropic imaging techniques such as serial block-face scanning electron microscopy (SBEM). Additionally, no assumptions about 3D organelle morphology are made, ensuring the method can be easily expanded to any number of structurally and functionally diverse organelles. Following the presentation of our algorithm, we validate its performance by assessing the segmentation accuracy of different organelle targets in an example SBEM dataset and demonstrate that it can be efficiently parallelized on supercomputing resources, resulting in a dramatic reduction in runtime

    Signal processing in local neuronal circuits based on activity-dependent noise and competition

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    We study the characteristics of weak signal detection by a recurrent neuronal network with plastic synaptic coupling. It is shown that in the presence of an asynchronous component in synaptic transmission, the network acquires selectivity with respect to the frequency of weak periodic stimuli. For non-periodic frequency-modulated stimuli, the response is quantified by the mutual information between input (signal) and output (network's activity), and is optimized by synaptic depression. Introducing correlations in signal structure resulted in the decrease of input-output mutual information. Our results suggest that in neural systems with plastic connectivity, information is not merely carried passively by the signal; rather, the information content of the signal itself might determine the mode of its processing by a local neuronal circuit.Comment: 15 pages, 4 pages, in press for "Chaos
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