An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples.

MalariaGEN is a data-sharing network that enables groups around the world to work together on the genomic epidemiology of malaria. Here we describe a new release of curated genome variation data on 7,000 Plasmodium falciparum samples from MalariaGEN partner studies in 28 malaria-endemic countries. High-quality genotype calls on 3 million single nucleotide polymorphisms (SNPs) and short indels were produced using a standardised analysis pipeline. Copy number variants associated with drug resistance and structural variants that cause failure of rapid diagnostic tests were also analysed.  Almost all samples showed genetic evidence of resistance to at least one antimalarial drug, and some samples from Southeast Asia carried markers of resistance to six commonly-used drugs. Genes expressed during the mosquito stage of the parasite life-cycle are prominent among loci that show strong geographic differentiation. By continuing to enlarge this open data resource we aim to facilitate research into the evolutionary processes affecting malaria control and to accelerate development of the surveillance toolkit required for malaria elimination

Asiakastyytyväisyystutkimus : Simon Auto Oy

Opinnäytetyön tarkoituksena oli selvittää Pihtiputaan Simon Auto Oy:n asiakkaiden tyytyväisyyttä. Asiakkaiden tyytyväisyyttä selvitettiin myymälään ja kahvioon, sijaintiin sekä asiakaspalveluun. Tutkimuksessa selvitettiin samalla myös asiakkaiden taustatietoja sekä asiointitiheyttä. Opinnäytetyön teoriaosuudessa käsitellään palvelun laatua, markkinointia yleisellä tasolla, asiakastyytyväisyyttä sekä erilaisia tutkimustyyppejä. Lähteinä opinnäytetyössä käytettiin palvelua, markkinointia, asiakastyytyväisyyttä sekä tilastollista tutkimusta käsittelevää kirjallisuutta. Asiakastyytyväisyystutkimus suoritettiin kyselylomakkeella Pihtiputaan Simon Auto Oy:ssä. Vastauksia saatiin yhteensä 29 kappaletta. Tutkimuksen tulosten perusteella asiakaspalvelun laatuun sekä myymälään ja kahvioon oltiin pääosin tyytyväisiä.The purpose of this thesis was to study the satisfaction of the customers of Simon Auto Oy. The aim was to find out customers’ satisfaction with the store, cafeteria, location and customer service. This study also examined customers’ backgrounds and density of transactions. The theoretical part of this thesis deals with the quality of service, marketing at a general level, customer satisfaction and different research types. The sources of this thesis represented literature that covered service, marketing, customer satisfaction and statistical research. The customer satisfaction research was carried out by using questionnaire which took place at the store. The total number of answers was 29. Based on the research results, the customers were mainly contented with the quality of the customer service and with the store and the cafeteria

An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples

MalariaGEN is a data-sharing network that enables groups around the world to work together on the genomic epidemiology of malaria. Here we describe a new release of curated genome variation data on 7,000 Plasmodium falciparum samples from MalariaGEN partner studies in 28 malaria-endemic countries. High-quality genotype calls on 3 million single nucleotide polymorphisms (SNPs) and short indels were produced using a standardised analysis pipeline. Copy number variants associated with drug resistance and structural variants that cause failure of rapid diagnostic tests were also analysed.  Almost all samples showed genetic evidence of resistance to at least one antimalarial drug, and some samples from Southeast Asia carried markers of resistance to six commonly-used drugs. Genes expressed during the mosquito stage of the parasite life-cycle are prominent among loci that show strong geographic differentiation. By continuing to enlarge this open data resource we aim to facilitate research into the evolutionary processes affecting malaria control and to accelerate development of the surveillance toolkit required for malaria elimination

An open dataset of <i>Plasmodium falciparum</i> genome variation in 7,000 worldwide samples.

MalariaGEN is a data-sharing network that enables groups around the world to work together on the genomic epidemiology of malaria. Here we describe a new release of curated genome variation data on 7,000 Plasmodium falciparum samples from MalariaGEN partner studies in 28 malaria-endemic countries. High-quality genotype calls on 3 million single nucleotide polymorphisms (SNPs) and short indels were produced using a standardised analysis pipeline. Copy number variants associated with drug resistance and structural variants that cause failure of rapid diagnostic tests were also analysed.  Almost all samples showed genetic evidence of resistance to at least one antimalarial drug, and some samples from Southeast Asia carried markers of resistance to six commonly-used drugs. Genes expressed during the mosquito stage of the parasite life-cycle are prominent among loci that show strong geographic differentiation. By continuing to enlarge this open data resource we aim to facilitate research into the evolutionary processes affecting malaria control and to accelerate development of the surveillance toolkit required for malaria elimination