1,047 research outputs found
Proprioceptive changes impair balance control in individuals with chronic obstructive pulmonary disease
Copyright @ 2013 Janssens et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.Introduction: Balance deficits are identified as important risk factors for falling in individuals with chronic obstructive pulmonary disease (COPD). However, the specific use of proprioception, which is of primary importance during balance control, has not been studied in individuals with COPD. The objective was to determine the specific proprioceptive control strategy during postural balance in individuals with COPD and healthy controls, and to assess whether this was related to inspiratory muscle weakness. Methods: Center of pressure displacement was determined in 20 individuals with COPD and 20 age/gender-matched controls during upright stance on an unstable support surface without vision. Ankle and back muscle vibration were applied to evaluate the relative contribution of different proprioceptive signals used in postural control. Results: Individuals with COPD showed an increased anterior-posterior body sway during upright stance (p=0.037). Compared to controls, individuals with COPD showed an increased posterior body sway during ankle muscle vibration (p=0.047), decreased anterior body sway during back muscle vibration (p=0.025), and increased posterior body sway during simultaneous ankle-muscle vibration (p=0.002). Individuals with COPD with the weakest inspiratory muscles showed the greatest reliance on ankle muscle input when compared to the stronger individuals with COPD (p=0.037). Conclusions: Individuals with COPD, especially those with inspiratory muscle weakness, increased their reliance on ankle muscle proprioceptive signals and decreased their reliance on back muscle proprioceptive signals during balance control, resulting in a decreased postural stability compared to healthy controls. These proprioceptive changes may be due to an impaired postural contribution of the inspiratory muscles to trunk stability. Further research is required to determine whether interventions such as proprioceptive training and inspiratory muscle training improve postural balance and reduce the fall risk in individuals with COPD.This work was supported by the Research Foundation – Flanders (FWO) grants 1.5.104.03, G.0674.09, G.0598.09N and G.0871.13N
Impaired Postural Control Reduces Sit-to-Stand-to-Sit Performance in Individuals with Chronic Obstructive Pulmonary Disease
Abstract
Background: Functional activities, such as the sit-to-stand-to-sit (STSTS) task, are often impaired in individuals with chronic
obstructive pulmonary disease (COPD). The STSTS task places a high demand on the postural control system, which has
been shown to be impaired in individuals with COPD. It remains unknown whether postural control deficits contribute to
the decreased STSTS performance in individuals with COPD.
Methods: Center of pressure displacement was determined in 18 individuals with COPD and 18 age/gender-matched
controls during five consecutive STSTS movements with vision occluded. The total duration, as well as the duration of each
sit, sit-to-stand, stand and stand-to-sit phase was recorded.
Results: Individuals with COPD needed significantly more time to perform five consecutive STSTS movements compared to healthy controls (1966 vs. 1364 seconds, respectively; p = 0.001). The COPD group exhibited a significantly longer stand phase (p = 0.028) and stand-to-sit phase (p = 0.001) compared to the control group. In contrast, the duration of the sit phase (p = 0.766) and sit-to-stand phase (p = 0.999) was not different between groups.
Conclusions: Compared to healthy individuals, individuals with COPD needed significantly more time to complete those phases of the STSTS task that require the greatest postural control. These findings support the proposition that suboptimal postural control is an important contributor to the decreased STSTS performance in individuals with COPD
Nutritional behaviour and beliefs of ski-mountaineers: a semi-quantitative and qualitative study.
BACKGROUND: Endurance athletes are advised to optimize nutrition prior to races. Little is known about actual athletes' beliefs, knowledge and nutritional behaviour. We monitored nutritional behaviour of amateur ski-mountaineering athletes during 4 days prior to a major competition to compare it with official recommendations and with the athletes' beliefs.
METHODS: Participants to the two routes of the 'Patrouille des Glaciers' were recruited (A, 26 km, ascent 1881 m, descent 2341 m, max altitude 3160 m; Z, 53 km, ascent 3994 m, descent 4090 m, max altitude 3650 m). Dietary intake diaries of 40 athletes (21 A, 19 Z) were analysed for energy, carbohydrate, fat, protein and liquid; ten were interviewed about their pre-race nutritional beliefs and behaviour.
RESULTS: Despite belief that pre-race carbohydrate, energy and fluid intake should be increased, energy consumption was 2416 ± 696 (mean ± SD) kcal · day(-1), 83 ± 17% of recommended intake, carbohydrate intake was only 46 ± 13% of minimal recommended (10 g · kg(-1) · day(-1)) and fluid intake only 2.7 ± 1.0 l · day(-1).
CONCLUSIONS: Our sample of endurance athletes did not comply with pre-race nutritional recommendations despite elementary knowledge and belief to be compliant. In these athletes a clear and reflective nutritional strategy was lacking. This suggests a potential for improving knowledge and compliance with recommendations. Alternatively, some recommendations may be unrealistic
Prostaglandin E2-like activity of 20:3n-9 platelet lipoxygenase end-product
Abstract5,8,11-Icosatrienoic acid (20:3n-9), a fatty acid associated with platelet hyperactivity, was oxygenated by platelet lipoxygenase. The end-product of this pathway was purified by high-performance liquid chromatography (HPLC) and characterized as 12-hydroxy-5,8,10-icosatrienoic acid [12-OH-20:3(5,8,10)] by capillary gas-liquid mass spectrometry. When tested upon platelet aggregation, 12-OH-20:3(5,8,10) exhibited a biphasic effect. At low concentrations (below 5 × 10−7 M) it potentiated aggregation but inhibited it at higher levels, a pattern similar to that obtained with prostaglandin E2. However, since the amounts of 12-OH-20:3(5,8,10) generated under thrombin stimulation are in the range of concentrations with potentiating effects, it seems that the 12-OH derivative is responsible for the hyperaggrebility of 20: 3n-9-rich platelets
New pixelized Micromegas detector for the COMPASS experiment
New Micromegas (Micro-mesh gaseous detectors) are being developed in view of
the future physics projects planned by the COMPASS collaboration at CERN.
Several major upgrades compared to present detectors are being studied:
detectors standing five times higher luminosity with hadron beams, detection of
beam particles (flux up to a few hundred of kHz/mm^2, 10 times larger than for
the present detectors) with pixelized read-out in the central part, light and
integrated electronics, and improved robustness. Studies were done with the
present detectors moved in the beam, and two first pixelized prototypes are
being tested with muon and hadron beams in real conditions at COMPASS. We
present here this new project and report on two series of tests, with old
detectors moved into the beam and with pixelized prototypes operated in real
data taking condition with both muon and hadron beams.Comment: 11 pages, 5 figures, proceedings to the Micro-Pattern Gaseous
Detectors conference (MPGD2009), 12-15 June 2009, Kolympari, Crete, Greece
Minor details added and language corrections don
Possible measurements of GPDs at COMPASS
This paper presents the reactions which can be performed at COMPASS to study
the Generalized Parton Distributions (GPDs). The high energy muon beam at CERN
allows to measure Hard Exclusive Meson Production or Deeply Virtual Compton
Scattering (DVCS) in the Bjorken regime in a large range of Q^2 and x_Bj
(1.5<Q^2<7.5 GeV^2 and 0.03<x_Bj<0.25). Exploratory measurements dedicated to
rho_0 or pi_0 production can be investigated with the present setup. DVCS
measurement require an upgrade of the COMPASS setup.Comment: 20 pages, 9 figure
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