Развитие рефлексии учебной деятельности слабослышащих студентов в условиях инклюзивной образовательной среды

Introduction. The article presents the results of a study of educational reflection among students with hearing impairments studying under the programs of secondary vocational education, in the process of classroom studies and in extracurricular activities. For this contingent of students, vocational education is one of the most important factors of social adaptation and professional rehabilitation, providing the opportunity for a full-fledged self-sufficient life. However, due to objective reasons, such students experience significant difficulties in the process of professional training.Purpose setting. There is a need to create a comprehensive system of pedagogical work for the development of the reflexive component of educational activity among this category of citizens.Methods and methodology of the study. The article reasonably proves that the organization of pedagogical work on the development of educational reflection, the ability to evaluate and control their educational and educational and professional activities can not only increase the effectiveness of the educational process, but will also contribute to the professional self-determination of students with hearing impairments. The article describes a system of diagnostic methods that allows to identify the current level of educational reflection in students; the system of pedagogical work is presented, which includes directions, techniques, methods and forms for the development of the reflexive component of educational activity among students with hearing impairment.Results. A diagnostic study showed that more than half of the students have a low level of development of the reflection of educational activity. The conditions necessary for the effective organization of pedagogical work to develop the reflection of educational activity were determined.Conclusions. It was found out that their development is facilitated by the immersion of students in educational activities that are personally significant for them. In turn, the formed skills of educational reflection facilitate the process of learning and professional self-determination of students.Введение. В статье приведены результаты исследования учебной рефлексии у студентов с нарушением слуха, обучающихся по программам среднего профессионального образования, в процессе аудиторных занятий и во внеучебной деятельности. Для этого контингента обучающихся профессиональное образование является одним из важнейших факторов социальной адаптации и профессиональной реабилитации, обеспечивая возможность полноценной самодостаточной жизни. Однако в силу объективных причин такие студенты испытывают значительные трудности в процессе профессиональной подготовки.Поставка задачи. Возникает необходимость в создании комплексной системы педагогической работы по развитию рефлексивного компонента учебной деятельности у этой категории граждан.Методика и методология исследования. В статье аргументированно доказывается, что организация педагогической работы по развитию учебной рефлексии, способности оценивать и контролировать свою учебную и учебно-профессиональную деятельность может не только повысить эффективность образовательного процесса, но и будет способствовать профессиональному самоопределению студентов с нарушениями слуха. В статье описана система диагностических методик, которая позволяет выявить актуальный уровень учебной рефлексии у студентов; представлена система педагогической работы, которая включает направления, приемы, методы и формы по развитию рефлексивного компонента учебной деятельности у студентов с нарушением слуха.Результаты. Диагностическое исследование показало, что у большей половины обучающихся низкий уровень развития рефлексии учебной деятельности. Определены условия, необходимые для эффективной организации педагогической работы по развитию рефлексии учебной деятельности.Выводы. Выявлено, что их развитию способствует погружение студентов в учебную деятельность, которая является личностно значимой для них. В свою очередь, сформированные навыки учебной рефлексии облегчают процесс обучения и профессионального самоопределения обучающихся

Effect of self-organization and properties of aqueous disperse systems based on the moss peptide PpCLE2 in a low concentration range on the growth of Arabidopsis thaliana roots

© 2017, Springer Science+Business Media, LLC, part of Springer Nature. It is shown for the first time using a complex of physicochemical methods (dynamic and electrophoretic light scattering, conductometry, pH-metry) that below a threshold concentration of 1.0•10 –7 mol L –1 the disperse phase of the aqueous systems based on moss peptide PpCLE2 undergoes the domain—nanoassociate rearrangement, which affects the nonmonotonic concentration dependences of the specific electrical conductivity and pH and can result in a multidirectional profile of the dependence of the growth of the primary and lateral roots of the Arabidopsis thaliana seed plant in the range of calculated concentrations from 1.0•10 –6 to 1.0•10 –12 mol L –1

A new class of glycomimetic drugs to prevent free fatty acid-induced endothelial dysfunction

Background: Carbohydrates play a major role in cell signaling in many biological processes. We have developed a set of glycomimetic drugs that mimic the structure of carbohydrates and represent a novel source of therapeutics for endothelial dysfunction, a key initiating factor in cardiovascular complications. Purpose: Our objective was to determine the protective effects of small molecule glycomimetics against free fatty acid­induced endothelial dysfunction, focusing on nitric oxide (NO) and oxidative stress pathways. Methods: Four glycomimetics were synthesized by the stepwise transformation of 2,5­dihydroxybenzoic acid to a range of 2,5­substituted benzoic acid derivatives, incorporating the key sulfate groups to mimic the interactions of heparan sulfate. Endothelial function was assessed using acetylcholine­induced, endotheliumdependent relaxation in mouse thoracic aortic rings using wire myography. Human umbilical vein endothelial cell (HUVEC) behavior was evaluated in the presence or absence of the free fatty acid, palmitate, with or without glycomimetics (1µM). DAF­2 and H2DCF­DA assays were used to determine nitric oxide (NO) and reactive oxygen species (ROS) production, respectively. Lipid peroxidation colorimetric and antioxidant enzyme activity assays were also carried out. RT­PCR and western blotting were utilized to measure Akt, eNOS, Nrf­2, NQO­1 and HO­1 expression. Results: Ex vivo endothelium­dependent relaxation was significantly improved by the glycomimetics under palmitate­induced oxidative stress. In vitro studies showed that the glycomimetics protected HUVECs against the palmitate­induced oxidative stress and enhanced NO production. We demonstrate that the protective effects of pre­incubation with glycomimetics occurred via upregulation of Akt/eNOS signaling, activation of the Nrf2/ARE pathway, and suppression of ROS­induced lipid peroxidation. Conclusion: We have developed a novel set of small molecule glycomimetics that protect against free fatty acidinduced endothelial dysfunction and thus, represent a new category of therapeutic drugs to target endothelial damage, the first line of defense against cardiovascular disease

Mathematical and hardware modelling of MST radar signals

The study examines the features of formation of radar signals, their structure, and software and hardware complex of MST radar. The results of formation of radar pulses with different types of phase and amplitude-phase modulation, as well as the results of generation of these pulses and their spectral analysis are presented. These results are obtained by using hardware based on PXI modules produced by National Instruments and Keysight and a software model created in the LabVIEW development environment. © 2020 Published under licence by IOP Publishing Ltd

Effect of self-organization and properties of aqueous disperse systems based on the moss peptide PpCLE2 in a low concentration range on the growth of Arabidopsis thaliana roots

© 2017, Springer Science+Business Media, LLC, part of Springer Nature. It is shown for the first time using a complex of physicochemical methods (dynamic and electrophoretic light scattering, conductometry, pH-metry) that below a threshold concentration of 1.0•10 –7 mol L –1 the disperse phase of the aqueous systems based on moss peptide PpCLE2 undergoes the domain—nanoassociate rearrangement, which affects the nonmonotonic concentration dependences of the specific electrical conductivity and pH and can result in a multidirectional profile of the dependence of the growth of the primary and lateral roots of the Arabidopsis thaliana seed plant in the range of calculated concentrations from 1.0•10 –6 to 1.0•10 –12 mol L –1

Effect of self-organization and properties of aqueous disperse systems based on the moss peptide PpCLE2 in a low concentration range on the growth of Arabidopsis thaliana roots

© 2017, Springer Science+Business Media, LLC, part of Springer Nature. It is shown for the first time using a complex of physicochemical methods (dynamic and electrophoretic light scattering, conductometry, pH-metry) that below a threshold concentration of 1.0•10 –7 mol L –1 the disperse phase of the aqueous systems based on moss peptide PpCLE2 undergoes the domain—nanoassociate rearrangement, which affects the nonmonotonic concentration dependences of the specific electrical conductivity and pH and can result in a multidirectional profile of the dependence of the growth of the primary and lateral roots of the Arabidopsis thaliana seed plant in the range of calculated concentrations from 1.0•10 –6 to 1.0•10 –12 mol L –1

Effect of self-organization and properties of aqueous disperse systems based on the moss peptide PpCLE2 in a low concentration range on the growth of Arabidopsis thaliana roots

© 2017, Springer Science+Business Media, LLC, part of Springer Nature. It is shown for the first time using a complex of physicochemical methods (dynamic and electrophoretic light scattering, conductometry, pH-metry) that below a threshold concentration of 1.0•10 –7 mol L –1 the disperse phase of the aqueous systems based on moss peptide PpCLE2 undergoes the domain—nanoassociate rearrangement, which affects the nonmonotonic concentration dependences of the specific electrical conductivity and pH and can result in a multidirectional profile of the dependence of the growth of the primary and lateral roots of the Arabidopsis thaliana seed plant in the range of calculated concentrations from 1.0•10 –6 to 1.0•10 –12 mol L –1

Spark Plasma Sintering of WC-Based 10wt%Co Hard Alloy: A Study of Sintering Kinetics and Solid-Phase Processes

The paper describes the method for producing WC-10wt%Co hard alloy with 99.6% of the theoretical density and a Vickers hardness of ~1400 HV 0.5. Experimental data on densification dynamics, phase composition, morphology, mechanical properties, and grain size distribution of WC-10%wtCo using spark plasma sintering (SPS) within the range of 1000–1200 °C are presented. The high quality of the product is provided by the advanced method of high-speed powder mixture SPS-consolidation at achieving a high degree of densification with minimal calculated grain growth at 1200 °C

Functionally Gradient Material Fabrication Based on Cr, Ti, Fe, Ni, Co, Cu Metal Layers via Spark Plasma Sintering

The paper presents a method of obtaining functionally graded material (FGM) of heterogeneous (layered) type based on joined metals Cr-Ti-Fe-Co-Ni-Cu using spark plasma sintering (SPS) technology. The structure, elemental and phase composition of FGM obtained on the basis of joined metals with different values of the temperature coefficient of linear expansion (CTLE) were studied by SEM, EDS and XRD methods with regard to the phase states of the alloy system. Based on the Vickers microhardness data, the evaluation of the mechanical characteristics of FGM in the whole sample body and locally at the contact boundaries of the joined metals was carried out. The results of the study are new and represent a potential for FGM, as well as functionally graded coatings (FGC), which have special physical, chemical and mechanical properties and are highly demanded for the manufacture of structures and products for industrial applications